IJOHNS  Vol.3 No.5 , September 2014
A Six-Year Review of Head and Neck Cancers at the Komfo Anokye Teaching Hospital, Kumasi, Ghana
ABSTRACT
Background: In Ghana, information on the prevalence and pattern of Head and Neck Cancers (HNCA) is scarce. There are few publications based on specific sub-sites of the head and neck, however, literature on the prevalence and pattern of HNCA in general is lacking. The present study aimed to describe the pattern of HNCA among patients seen at the multidisciplinary HNCA clinic of Komfo Anokye Teaching Hospital. Methods: This is a retrospective review of all consecutive patient records seen at the multidisciplinary clinic from 2004 to 2009. Results: There were 149 males and 103 females giving a male to female ratio of 1.45:1. The age range was 2 - 95 years with a mean of 48.1 years. The commonest type of HNCA in this review is cancers of the oral cavity (29.4%), followed by accessory sinuses (13.9%) and larynx (13.5%). Nasopharyngeal cancer affected young people, with 34.5% of affected patients aged between 10 and 19 years. The commonest histopathological type was squamous cell carcinoma (49.6%). Majority (47.6%) of patients presented at stage IV. Conclusion: The commonest HNCA is oral cancer. Majority of patients with HNCA are presenting late calling for public health education to raise awareness and promote early detection.

Cite this paper
Larsen-Reindorf, R. , Owusu-Afriyie, O. , Acheampong, A. , Boakye, I. and Awuah, B. (2014) A Six-Year Review of Head and Neck Cancers at the Komfo Anokye Teaching Hospital, Kumasi, Ghana. International Journal of Otolaryngology and Head & Neck Surgery, 3, 271-278. doi: 10.4236/ijohns.2014.35050.
References
[1]   Pai, S.I. and Westra, W.H. (2009) Molecular Pathology of Head and Neck Cancer: Implications for Diagnosis, Prognosis, and Treatment. Annual Review of Pathology, 4, 49-70.
http://dx.doi.org/10.1146/annurev.pathol.4.110807.092158

[2]   Boffetta, P. and Hashibe, M. (2006) Alcohol and Cancer. The Lancet Oncology, 7, 149-156.
http://dx.doi.org/10.1016/S1470-2045(06)70577-0

[3]   Manur, S. and Forastiere, A.A. (2008) Head and Neck Cancer: Changing Epidemiology, Diagnosis, and Treatment. Mayo Clinic Proceedings, 83, 489-501.
http://dx.doi.org/10.4065/83.4.489

[4]   Hennessey, P.T., Westra, W.H. and Califana, J.A. (2009) Human Papillomavirus and Head and Neck Squamous Cell Carcinoma: Recent Evidence and Clinical Implications. Journal of Dental Research, 88, 300-306.
http://dx.doi.org/10.1177/0022034509333371

[5]   Garfinkel, L. (1995) Perspective on Cancer Prevention. A Cancer Journal for Clinicians, 45, 5-9.
http://dx.doi.org/10.3322/canjclin.45.1.5

[6]   Tobias, J. (1994) Cancer of the Head and Neck. BMJ, 308, 961-966.
http://dx.doi.org/10.1136/bmj.308.6934.961

[7]   Zagar, G., Smith, J., Norante, J. and McDonald, S. (1993) Tumours of the Head and Neck. In: Rubin, P., Ed., Clinical Oncology: A Multidisciplinary Approach for Physicians and Students, W.B. Saunders, Baltimore, 319-362.

[8]   Watkinson, J., Gaze, M. and Wilson, J. (2000) Stella and Maran’s Head and Neck Surgery. 4. Butterworth Heinemann, Oxford, 1-9.

[9]   Sanghvi, L.D., Rao, D.N., and Joshi, S. (1989) Epidemiology of Head and Neck Cancer. Seminars in Surgical Oncology, 5, 305-309.
http://dx.doi.org/10.1002/ssu.2980050503

[10]   Adeyemi, B.F., Adekunle, L.V., Kolude, B.M., Akang, E.E.U. and Lawoyin, J.O. (2008) Head and Neck Cancer—A Clinicopathological Study in a Tertiary Care Center. Journal of the National Medical Association, 100, 690-697.

[11]   Kitcher, E., Yarney, J., Gyasi, R. and Cheyuo, C. (2006) Laryngeal Cancer at the Korle-Bu Teaching Hospital Accra Ghana. Ghana Medical Journal, 40, 45-49.

[12]   Abdulai, A.E., Nuamah, I.K. and Gyasi, R. (2012) Head and Neck Tumours in Ghanaian Children. A 20 Year Review. International Journal of Oral & Maxillofacial Surgery, 41, 1378-1382.
http://dx.doi.org/10.1016/j.ijom.2012.06.004

[13]   Bhatia, P. (1990) Head and Neck Cancer in Plateau State of Nigeria. West African Journal of Medicine, 9, 304-310.

[14]   Otoh, E.C., Johnson, N., Danfillo, I.S., Adeleke, O.A. and Olasoji, H.A. (2004) Primary Head and Neck Cancers in North Eastern Nigeria. West African Journal of Medicine, 23, 305-313.

[15]   Amusa, Y.B., Olabanji, J.K., Akinpelu, V.O., Ogundipe, O.V., Olateju, S.O., Agbakwuru, E.A., Ndukwe, N., Fatusi, O.A. and Ojo, O.S. (2004) Pattern of Head and Neck Malignant Tumours in a Nigerian Teaching Hospital—A Ten Year Review. West African Journal of Medicine, 23, 280-285.

[16]   Nwawolo, C., Ajekigbe, A., Oyeneyin, J., Nwankwo, K. and Okeowo, P. (2001) Pattern of Head and Neck Cancers among Nigerians in Lagos. West African Journal of Medicine, 20, 111-116.

[17]   Da Lilly-Tariah, O.B., Somefun, A.O. and Adeyemo, W.L. (2009) Current Evidence on the Burden of Head and Neck Cancers in Nigeria. Head & Neck Oncology, 1, 14.
http://dx.doi.org/10.1186/1758-3284-1-14

[18]   Onyango, J.F. and Macharia, I.M. (2006) Delays in Diagnosis, Referral and Management of Head and Neck Cancer Presenting at Kenyatta National Hospital, Nairobi. East African Medical Journal, 83, 85-91.
http://dx.doi.org/10.4314/eamj.v83i4.9421

[19]   Onyango, J.F., Awange, D.O., Njiru, A. and Macharia, I.M. (2006) Pattern of Occurrence of Head and Neck Cancer Presenting at Kenyatta National Hospital, Nairobi. East African Medical Journal, 83, 288-291.
http://dx.doi.org/10.4314/eamj.v83i5.9435

[20]   Abdul-Hamid, G., Saeed, N.M., Al-Kahiry, W. and Shukry, S. (2010) Pattern of Head and Neck Cancer in Yemen. Gulf Journal of Oncology, 7, 21-24.

[21]   Altumbabic, H., Salkic, A., Ramas, A., Burgic, M., Kasumovic, M. and Brkic, F. (2008) Pattern of Head and Neck Malignant Tumours in a Tuzla ENT Clinic—A Five Year Experience. Bosnian Journal of Basic Medical Sciences, 8, 377-380.

[22]   Donkor, P. and Boateng, K.A. (2000) Prevalence of Orofacial Squamous Cell Carcinoma Sfeen at Komfo Anokye Teaching Hospital. Ghana Medical Journal, 34, 139-143.

[23]   Adham, M., Kurniawan, A.N., Muhtadi, A.I., Roezin, A., Hermani, B., Gondhowiardjo, S., Tan, I.B. and Middeldorp, J.M. (2012) Nasopharyngeal Carcinoma in Indonesia: Epidemiology, Incidence, Signs, and Symptoms at Presentation. Chinese Journal of Cancer, 31, 185-196.

 
 
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