OJOG  Vol.4 No.13 , September 2014
Management and Results of Ectopic Pregnancy Adapted by Clinical Guidelines: Two Years Experience of University Hospital in Turkey
Ectopic pregnancy is defined as the fertilized ovum implants in a location outside the endometrial cavity, remains to be an important cause of maternal morbidity and mortality worldwide and is a health problem with incidence ranges between 0.25% and 2% of all pregnancies. In our study, in Izmir Katip Celebi University Ataturk Training and Research Hospital, Department of Obstetrics and Gynecology from 2011 to 2013, 96 cases with diagnosis of ectopic pregnancy managed by the adapted RCOG’s Guide were analyzed retrospectively. The data were analyzed as follows: age, the history of operation, smoking, the presence of intrauterine device, blood groups, hemoglobin, platelets, values of B-hCG, the diagnostic interval, intra-abdominal free fluid and/or acute abdomen, the method of treatment and the success of treatment.

Cite this paper
Aydogmus, S. , Eris, S. , Aydogmus, H. , Tanrısever, G. , Selim, H. , Caltekin, M. , Seyhanlı, Z. and Kelekci, S. (2014) Management and Results of Ectopic Pregnancy Adapted by Clinical Guidelines: Two Years Experience of University Hospital in Turkey. Open Journal of Obstetrics and Gynecology, 4, 766-770. doi: 10.4236/ojog.2014.413106.
[1]   Omokanye, L.O., Balogun, O.R., Salaudeen, A.G., Olatinwo, A.W. and Saidu, R. (2013) Ectopic Pregnancy in Ilorin, Nigeria: A Four Year Review. Nigerian Postgraduate Medical Journal, 20, 341-345.

[2]   Ayaz, A., Emam, S. and Farooq, M.U. (2013) Clinical Course of Ectopic Pregnancy: A Single-Center Experience. Journal of Human Reproductive Sciences, 6, 70-73. http://dx.doi.org/10.4103/0974-1208.112386

[3]   Yao, M. and Tulandi, T. (1997) Current Status of Surgical and Nonsurgical Management of Ectopic Pregnancy. Fertility and Sterility, 67, 421. http://dx.doi.org/10.1016/S0015-0282(97)80064-7

[4]   Royal College of Obstetricians and Gynaecologists (2010) The Management of Tubal Pregnancy. RCOG Guideline No. 21.

[5]   Vaswani, P. and Vaswani, R. (2013) Evaluation of Risk Factors for Ectopic Pregnancy among Women Attending a Tertiary Care Hospital in United Arab Emirates: A Case Control Study. Sri Lanka Journal of Obstetrics and Gynaecology, 35, 53-57.

[6]   Handler, A., Davis, F., Ferre, C. amd Yeko, T. (1989) The Relationship of Smoking and Ectopic Pregnancy. American Journal of Public Health, 79, 1239-1242.

[7]   Coste, J., Job-Spira, N. and Fernandez, H. (1991) Increased Risk of Ectopic Pregnancy with Maternal Cigarette Smoking. American Journal of Public Health, 81, 199-201.

[8]   Bouyer, J., Coste, J., Shojaei, T., Pouly, J.L., Fernandez, H., Gerbaud, L. and Job-Spira, N. (2003) Risk Factors for Ectopic Pregnancy: A Comprehensive Analysis Based on a Large Case-Control, Population-Based Study in France. American Journal of Epidemiology, 157, 185-194. http://dx.doi.org/10.1093/aje/kwf190

[9]   Thorburn, J., Philipson, M. and Lindblom, B. (1986) Background Factors of Ectopic Pregnancy: II. Risk Estimation by Means of a Logistic Model. European Journal of Obstetrics, Gynecology, and Reproductive Biology, 23, 333-340. http://dx.doi.org/10.1016/0028-2243(86)90168-1

[10]   Makinen, J.I. (1989) Increase of Ectopic Pregnancies in Finland. Combination of Time and Cohort Effect. Obstetrics and Gynecology, 73, 21-24.

[11]   Arup, K.M., Niloptal, R., Kakali, S.K. and Pradip, K.B. (2007) Ectopic Pregnancy: An Analysis of 180 Cases. Journal of the Indian Medical Association, 105, 308-314.

[12]   Menon, S., Colins, J. and Barnhart, K.T. (2007) Establishing a Human Chorionic Gonadotropin Cutoff to Guide Methotrexate Treatment of Ectopic Pregnancy: A Systematic Review. Fertility and Sterility, 87, 481-484. http://dx.doi.org/10.1016/j.fertnstert.2006.10.007

[13]   Sowter, M., Farquhar, C. and Gudex, G. (2001) An Economic Evaluation of Single Dose Systemic Methotrexate and Laparoscopic Surgery for the Treatment of Unruptured Ectopic Pregnancy. British Journal of Obstetrics and Gynaecology, 108, 204-212.

[14]   Mol, B., Hajenius, P., Engelsbel, S., Ankum, W., Hemrika, D., Van der Veen, F. and Bossuyt, P.M.M. (1999) Treatment of Tubal Pregnancy in the Netherlands: An Economic Comparison of Systemic Methotrexate Administration and Laparoscopic Salpingostomy. American Journal of Obstetrics & Gynecology, 181, 945-951. http://dx.doi.org/10.1016/S0002-9378(99)70330-3

[15]   Lipscomb, G., McCord, M., Stovall, T., Huff, G., Portera, S. and Ling, F. (1999) Predictors of Success of Methotrexate Treatment in Women with Tubal Ectopic Pregnancies. New England Journal of Medicine, 341, 1974-1978. http://dx.doi.org/10.1056/NEJM199912233412604

[16]   Sowter, M. and Frappell, J. (2002) The Role of Laparoscopy in the Management of Ectopic Pregnancy. Reviews in Gynaecological Practice, 2, 73-82. http://dx.doi.org/10.1016/S1471-7697(02)00007-2

[17]   Mol, F., Mol, B.W., Ankum, W.M., Van der Veen, F. and Hajenius, P.J. (2008) Current Evidence on Surgery, Systemic Methotrexate and Expectant Management in the Treatment of Tubal Ectopic Pregnancy: A Systematic Review and Meta-Analysis. Human Reproduction Update, 14, 309-319. http://dx.doi.org/10.1093/humupd/dmn012

[18]   Hajenius, P.J., Mol, F., Mol, B.W., Bossuyt, P.M., Ankum, W.M. and Van der Veen, F. (2007) Interventions for Tubal Ectopic Pregnancy. Cochrane Database of Systematic Reviews, 24, Article ID: CD000324.

[19]   Seeber, B.E. and Barnhart, K.T. (2006) Suspected Ectopic Pregnancy. Obstetrics and Gynecology, 107, 399-413. Erratum. Obstetrics and Gynecology, 107, 955.

[20]   Seifer, D.B., Gutman, J.N., Grant, W.D., Kamps, C.A. and DeCherney, A.H. (1993) Comparison of Persistent Ectopic Pregnancy after Laparoscopic Salpingostomy versus Salpingectomy at Laparotomy for Ectopic Pregnancy. Obstetrics and Gynecology, 81, 378-382.