JCDSA  Vol.4 No.4 , September 2014
Preparation of Microcapsules Containing Triple Core Materials with Interfacial Condensation Reaction
Abstract
In this manuscript, we describe the novel method for preparing the microcapsules containing α-tocopherol oil droplets as the first core material, calcium chloride powder as the second core material and the fine water droplets as the third core material by the interfacial condensation reaction between hydroxyl propyl methyl cellulose and tannic acid. The interfacial condensation reaction was performed between hydroxyl propyl methyl cellulose dissolved in the continuous water phase and tannic acid dissolved in the inner fine water droplets as the third core material. The calcium chloride powder as the second core material was dispersed in the α-tocopherol oil droplet as the first core material beforehand. The α-tocopherol oil containing the second and the third core materials was dispersed in the continuous water phase to form the [(S + W)/O/W] emulsion. The α-tocopherol oil as the first core material was microencapsulated satisfactorily and the contents of the second core material were increased with the concentration of stearic acid as the oil soluble stabilizer. The mechanical strength of microcapsules increased with the concentration of hydroxyl propyl methyl cellulose. Thermal energy could be released by breaking the microcapsules in water and by dissolving calcium chloride in the continuous water phase.

Cite this paper
Taguchi, Y. , Aoki, M. and Tanaka, M. (2014) Preparation of Microcapsules Containing Triple Core Materials with Interfacial Condensation Reaction. Journal of Cosmetics, Dermatological Sciences and Applications, 4, 275-283. doi: 10.4236/jcdsa.2014.44037.
References

[1]   Kondo, T. and Tanaka, M. (1975) Microcapsules (Preparation, Properties, Application). Sankyo Shuppan, Tokyo.

[2]   Kondo, T. (1967) Saishin Maikurokapseruka Gijutsu (Microencapsulation Technique). TES, Tokyo.

[3]   Tanaka, M. (2008) Key Point of Preparation of Nano/Microcapsules. Techno System Publishing Co. Ltd., Tokyo.

[4]   Koishi, M., Eto, K. and Higure, H. (2005) (Preparation + Utilization) Microcapsules. Kogyo Chosakai, Tokyo.

[5]   Somchue, W., Sermsri, W., Shiowatana, J. and Siripinyanond, A. (2009) Encapsulation of α-Tocopherol in Protein-Based Delivery Particles. Food Research International, 42, 909-914.
http://dx.doi.org/10.1016/j.foodres.2009.04.021

[6]   Song, Y.B., Lee, J.S. and Lee, H.G. (2009) α-Tocopherol-Loaded Ca-Pectinate Microcapsules: Optimization, in Vitro Release, and Bioavailability. Colloids and Surfaces B: Biointerfaces, 73, 394-398. http://dx.doi.org/10.1016/j.colsurfb.2009.06.014

[7]   Sato, H., Taguchi, Y. and Tanaka, M. (2014) Development of Preparation Method for Microencapsulating Uycalyptus Oil Containing Fine Aqueous Droplets by Use of Interfacial Condensation Reaction between Hydroxy Propyl Methyl Cellulose and Tannic Acid. Journal of Cosmetics, Dermatological Sciences and Applications, 4, 219-227.
http://dx.doi.org/10.4236/jcdsa.2014.44030

[8]   Costoyas, á., Ramos, J. and Forcada, J. (2009) Encapsulation of Silica Nanoparticles by Miniemulsion Polymerization. Journal of Polymer Science: Part A: Polymer Chemistry, 47, 935-948.
http://dx.doi.org/10.1002/pola.23212

[9]   Slobodian, P., Pavlínek, V., Lengálová, A. and Sáha, P. (2009) Polystyrene/Multi-Wall Carbon Nanotube Composites Prepared by Suspension Polymerization and Their Electrorheological Behavior. Current Applied Physics, 9, 184-188. http://dx.doi.org/10.1016/j.cap.2008.01.008

[10]   Takahashi, M., Taguchi, Y. and Tanaka, M. (2009) Microencapsulation of Hydrophilic Solid Powder as a Fire Retardant by the Method of in Situ Gelation in Droplets Using a Non-Aqueous Solvent as the Continuous Phase. Polymers & Polymer Composites, 17, 83-90.

[11]   Takahashi, M., Taguchi, Y. and Tanaka, M. (2010) Microencapsulation of Hydrophilic Solidpowder as a Flame Retardant with Epoxyresin by Using Interfacial Reaction Method. Polymers for Advanced Technologies, 21, 224-228.

[12]   Sawatari, N., Fukuda, M., Taguchi, Y. and Tanaka, M. (2004) The Effect of Surface Treatment of Magnetite Powder on a Structure of Composite Particles Prepared by Suspension Polymerization. Journal of Chemical Engineering of Japan, 37, 731-736. http://dx.doi.org/10.1252/jcej.37.731

 
 
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