Although upper GI
endoscopy is considered to be a gold standard in diagnosis of many pediatric
gastrointestinal disorders, there is limited data about its utility from
developing countries. We carried out this retrospective study at Aga khan
University Hospital, Karachi, Pakistan from 2008-2012. During the study period,
a total of 200 procedures were performed. Mean age of patients was 8.5 years.
66% of patients received general anesthesia for the procedure. Failure to
thrive with suspected coeliac disease was the most common indication for the
procedure, seen in 31% of patients. Gastritis was the most common abnormal
endoscopic finding, seen in 14.5% of patients. Gastritis was the most common
histopathological finding on biopsy, seen in 31% of the patients (n = 62).
Findings were consistent with
coeliac disease in 18% (n = 36), duodenitis, 10.5% (n = 21) and esophagitis, 4% (n = 8) of patients. No immediate post
procedure complication was noted in our study.
Cite this paper
Khan, M. , Ahmed, S. , Ali, S. , Maheshwari, P. and Jamal, M. (2014) Spectrum of Upper GI Endoscopy in Pediatric Population at a Tertiary Care Centre in Pakistan. Open Journal of Pediatrics
, 180-184. doi: 10.4236/ojped.2014.43025
 El-Mouzan, M.I., Abdullah, A.M., Al-Sanie, A.M., et al. (2001) Pattern of Gastro Esophageal Reflux in Children. Saudi Medical Journal, 22, 419-422.
 Sircus, W. (2003) Milestones in the Evolution of Endoscopy: A Short History. Journal of the Royal College of Physicians of Edinburgh, 33, 124-134.
 Haight, M. and Thomas, D.W. (1995) Pediatric Gastrointestinal Endoscopy. Gastroenterologist, 3, 181-186.
 Franciosi, J.P., Fiorino, K., Ruchelli, E., et al. (2010) Changing Indications for Upper Endoscopy in Children during a 20-Year Period. Journal of Pediatric Gastroenterology & Nutrition, 51, 443-447.
 Papp, J.P. (1973) Endoscopic Experience in 100 Consecutive Cases with the Olympus GIG Endoscope. The American Journal of Gastroenterology, 60, 466-472.
 Gleason, W.A., Tedesco, F.J., Keating, J.P., et al. (1974) Fiber Optic Gastrointestinal Endoscopy in Infants and Children. The Journal of Pediatrics, 85, 810-813. http://dx.doi.org/10.1016/S0022-3476(74)80347-1
 Graham, D.Y., Klish, W.J., Ferry, G.D., et al. (1978) Value of Fiber Optic Gastrointestinal Endoscopy in Infants and Children. Saudi Medical Journal, 71, 558-560. http://dx.doi.org/10.1097/00007611-197805000-00022
 Ginger, M.A. (2001) Gastroenterologic Endoscopy in Children: Past, Present and Future. Current Opinion in Pediatric, 13, 429-434. http://dx.doi.org/10.1097/00008480-200110000-00008
 Okello, T.R. (2006) Upper Gastrointestinal Endoscopic Findings in Adolescents at Lacor Hospital, Uganda. African Health Sciences, 6, 39-42.
 El-Mouzan, M.I., Al-Mofleh, I.A., Abdullah, A.M., et al. (2004) Indications and Yield of Upper Gastrointestinal Endoscopy in Children. Saudi Medical Journal, 25, 1223-1225.
 Aduful, H., Naaeder, S., Darko, R., et al. (2007) Upper Gastrointestinal Endoscopy at the Korle Bu Teaching Hospital, Accra, Ghana. Ghana Medical Journal, 41, 12-16.
 Murray, J.A., Van Dyke, C., Plevak, M.F., et al. (2003) Trends in the Identification and Clinical Features of Celiac Disease in a North American Community, 1950-2001. Clinical Gastroenterology and Hepatology, 1, 19-27.
 Joshi, M.R., Sharma, S.K. and Baral, M.R. (2005) Upper GI Endoscopy in Children- in an Adult Suite. Kathmandu University Medical Journal (KUMJ), 3, 111-114.
 Mudawi, H.M., El Tahir, M.A., Suleiman, S.H., et al. (2009) Paediatric Gastrointestinal Endoscopy: Experience in a Sudanese University Hospital. Eastern Mediterranean Health Journal, 15, 1027-1031.
 Hafeez, A., Ali, S. and Hassan, M. (2000) An Audit of Pediatric Upper Gastrointestinal Endoscopies. Journal of the College of Physicians and Surgeons Pakistan, 10, 13-15.
 Jantchou, P., Schirrer, J. and Bocquet, A. (2007) Appropriateness of Upper Gastrointestinal Endoscopy in Children: A Retrospective Study. Journal of Pediatric Gastroenterology and Nutrition, 44, 440-445.
 Quine, M.A., Bell, G.D., McCloy, R.F., et al. (1994) Appropriate Use of Upper Gastrointestinal Endoscopy—A Prospective Audit. Steering Group of the Upper Gastrointestinal Endoscopy Audit Committee. Gut, 35, 1209-1214.
 Bishop, P.R., Nowicki, M.J., May, W.L., et al. (2002) Unsedated Upper Endoscopy in Children. Gastrointestinal Endoscopy, 55, 624-630. http://dx.doi.org/10.1067/mge.2002.123417
 Armstrong, D., Barkun, A., Bridges, R., et al. (2012) Canadian Association of Gastroenterology Consensus Guidelines on Safety and Quality Indicators in Endoscopy. Canadian Journal of Gastroenterology, 26, 17-31.
 ASGE Standards of Practice Committee, Ben-Menachem, T., Decker, G.A., et al. (2012) Adverse Events of Upper GI Endoscopy. Gastrointestinal Endoscopy, 76, 707-718. http://dx.doi.org/10.1016/j.gie.2012.03.252