Pulmonary Tuberculosis (PTB) and Community-Acquired Pneumonia (CAP) are common causes of consolidation patch in chest radiograph. Sputum Z-N staining is positive in 30% to 60% cases only and sputum examination has poor yield in CAP. This study aimed to assess the value of serum Procalcitonin (PCT) levels in patients with Pulmonary Tuberculosis (PTB) and Community-Acquired Pneumonia (CAP). Patients with new opacity in chest radiograph were included in the study. Serum sample were taken at admission and stored. Patient’s diagnosis were confirmed and categorized into pulmonary TB group (32) and community-acquired pneumonia group (23). Their mean PCT level was compared with mean PCT level of 25 controls. Serum procalcitonin levels were found to be significantly elevated in patients of community-acquired pneumonia as compared to patients of pulmonary tuberculosis. In presence of consolidation in x-ray chest, increased level of serum procalcitonin might be used to differentiate pulmonary tuberculosis from community-acquired pneumonia. High level of serum procalcitonin was associated with high mortality rate in community-acquired pneumonia patients.
 Lim, W.S., Macfarlane, J.T., Boswell, T.C., et al. (2001) Study of Community-Acquired Pneumonia Aetiology (SCAPA) in Adults Admitted to Hospital: Implications for Management Guidelines. Thorax, 56, 296-301.
 Lieberman, D., Lieberman, D., Schlaeffer, F. and Porath, A. (1997) Community-Acquired Pneumonia in Old Age: A Prospective Study of 91 Patients Admitted from Home. Age Ageing, 26, 69-75.
 Kaplan, V., Angus, D.C., Griffin, M.F., Clermont, G., Scott, W.R. and Linde-Zwirble, W.T. (2002) Hospitalized Community-Acquired Pneumonia in the Elderly: Age- and Sex-Related Patterns of Care and Outcome in the United States. American Journal of Respiratory and Critical Care Medicine, 165, 766-772.
 Schuetz, P., Koller, M., Christ-Crain, M., et al. (2008) Predicting Mortality with Pneumonia Severity Scores: Importance of Model Recalibration to Local Settings. Epidemiology and Infection, 136, 1628-1637.
 Schuetz, P., Suter-Widmer, I., Chaudri, A., Christ-Crain, M., Zimmerli, W. and Mueller, B. for the Procalcitonin-Guided Antibiotic Therapy and Hospitalisation in Patients with Lower Respiratory Tract Infections (ProHOSP) Study Group (2011) Prognostic Value of Procalcitonin in Community-Acquired Pneumonia. European Respiratory Journal, 37, 384-392.
 Ugajin, M., Miwa, S., Shirai, M., Ohba, H., Eifuku, T., Nakamura, H., Suda, T., Hayakawa, H. and Chida, K. (2011) Usefulness of Serum Procalcitonin Levels in Pulmonary Tuberculosis. European Respiratory Journal, 37, 371-375.
 Schleicher, G.K., Herbert, V., Brink, A., Martin, S., Maraj, R., Galpin, J.S. and Feldman, C. (2005) Procalcitonin and C-Reactive Protein Levels in HIV-Positive Subjects with Tuberculosis and Pneumonia. European Respiratory Journal, 25, 688-692.