Diabetic Renal-Retinal Syndrome and Inflammatory Markers of Acute Phase

Francisco Jesús  Sepúlveda-Cañamar; Raúl Treviño  Hernández; Joaquín Darío Treviño  Baéz; Jesús H. González  Cortés

doi:10.4236/jdm.2014.43028

Journals by Subject

Journals by Title

JDM Vol.4 No.3 , August 2014

Diabetic Renal-Retinal Syndrome and Inflammatory Markers of Acute Phase

Francisco Jesús Sepúlveda-Cañamar, Raúl Treviño Hernández, Joaquín Darío Treviño Baéz, Jesús H. González Cortés

Abstract: Objective: To determine the association between the acute inflammatory markers and Diabetic Renal-Retinal Syndrome in our patients. Methods: A total of 44 patients were included in this transverse (cross sectional), observational, analytical, and comparative study. Two groups of patients were created. Results: In patients with chronic renal failure, stages 3, 4, or 5 (scale 1 to 5) were identified and divided into two groups: Group I (Patients with concomitant diabetic retinopathy stabilized with photocoagulation) 22 patients. Group II (Patients with progression of retinopathy, after photocoagulation, in the form of intraocular bleeding) 22 patients. The number of patients with chronic renal failure in stage 3 was: Group I; 16. In Group II; 12 patients (OR: 1.0). Stage 4: Group I; 4 patients. Group II: 3 patients (OR: 1.0, CI 95%; 0.3843 - 2.021). Stage 5: Group I; 2 patients. Group II; 7 patients (OR: 1.8148, CI 95%; 1.0448 - 3.1523; Chi-squared (x2) 2.7450, p = 0.097). t-Test found statistical significance in Erythrocyte Sedimentation Rate (ESR): p < 0.0001 (CI 95%; 7.8959 - 23.2515); R = 0.56 p = 0.001; and OR = 1.959 (CI 95%; 1.193 - 3.217). By non-parametric tests, C-reactive protein with binomial test showed p < 0.001. ESR showed p < 0.001 with U of Mann Whitney. Conclusions: With this study revealed a possible association of inflammatory markers with Diabetic Renal-Retinal Syndrome.

Keywords: Diabetic Renal-Retinal Syndrome, Erythrocyte Sedimentation Rate, C-Reactive Protein

Cite this paper: Sepúlveda-Cañamar, F. , Hernández, R. , Baéz, J. and Cortés, J. (2014) Diabetic Renal-Retinal Syndrome and Inflammatory Markers of Acute Phase. Journal of Diabetes Mellitus, 4, 194-201. doi: 10.4236/jdm.2014.43028.

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