JCDSA  Vol.4 No.4 , September 2014
Development of Preparation Method for Microencapsulating Uycalyptus Oil Containing Fine Aqueous Droplets by Use of Interfacial Condensation Reaction between Hydroxy Propyl Methyl Cellulose and Tannic Acid

It was tried to develop the preparation method for microencapsulating the uycalyptus oil containing fine aqueous droplets by using the interfacial condensation reaction between hydroxyl propyl methyl cellulose and tannic acid. Uycalyptus oil containing fine aqueous droplets was dispersed in the continuous water phase to form the (W/O)/W emulsion. Tannic acid and hydroxyl propyl methyl cellulose were dissolved in the inner aqueous droplets and in the outer continuous water phase, respectively. Tannic acid transferred through the oil phase from the inner water droplets to the interface between the oil phase and the continuous water phase and then, reacted with hydroxyl propyl methyl cellulose. In the experiment, the concentrations of hydroxyl propyl methyl cellulose and tannic acid were mainly changed stepwise. The uycalyptus oil containing the fine water droplets could be microencapsulated satisfactorily. It was found that the microcapsules were composed of the gelated hydroxyl propyl methyl cellulose film as the shell, the fine aqueous droplets as the first core and the oil droplet as the second core.

Cite this paper: Sato, H. , Taguchi, Y. and Tanaka, M. (2014) Development of Preparation Method for Microencapsulating Uycalyptus Oil Containing Fine Aqueous Droplets by Use of Interfacial Condensation Reaction between Hydroxy Propyl Methyl Cellulose and Tannic Acid. Journal of Cosmetics, Dermatological Sciences and Applications, 4, 219-227. doi: 10.4236/jcdsa.2014.44030.

[1]   Kondo, T. (1967) Saishin Maikurokapseruka Gijutsu (Microencapsulation Technique). TES, Tokyo.

[2]   Tanaka, M. (2008) Key Point of Preparation of Nano/Microcapsules. Techno System Publishing Co. Ltd., Tokyo.

[3]   Koishi, M., Eto, K. and Higure, H. (2005) (Preparation + Utilization) Microcapsules. Kogyo Chosakai, Tokyo.

[4]   Wang, J.M., Zheng, W., Song, Q.W., Zhu, H. and Zhou, Y. (2009) Preparation and Characterization of Natural Fragrant Microcapsules. Journal of Fiber Bioengineering and Informatics, 1, 293-300.

[5]   Lee, H., Jeong, C., Ghafoor, K., Cho, S. and Park, J. (2011) Oral Delivery of Insulin Using Chitosan Capsules Cross-Linked with Phytic Acid. Bio-Medical Materials and Engineering, 21, 25-36.

[6]   Suthaphot, N., Chulakup, S., Chonsakorn, S. and Mongkholrattanasit, R. (2012) Application of Aroma Therapy on Cotton Fabric by Microcapsules. International Conference: Textiles & Fashion 2012, Bangkok, 3-4 July 2014.

[7]   Satapathy, D., Biswas, D., Behera, B., Sagiri, S.S., Pal, K. and Pramanik, K. (2013) Sunflower-Oil-Based Lecithin Organogels as Matrices for Controlled Drug Delivery. Journal of Applied Polymer Science, 129, 585-594.

[8]   Hsieha, W.C., Changb, C.P. and Gaoc, Y.L. (2006) Controlled Release Properties of Chitosan Encapsulated Volatile Citronella Oil Microcapsules by Thermal Treatments. Colloids and Surfaces B: Biointerfaces, 53, 209-214.

[9]   Iamrungraksa, T. and Charuchinda, S. (2010) Preparation and Characteristics of Galangal Essential Oil/Alginate Microcapsules. Journal of Metals, Materials and Minerals, 20, 89-92.

[10]   Soliman, E.A., El-Moghazy, A.Y., Mohy El-Din, M.S. and Massoud, M.A. (2013) Microencapsulation of Essential Oils within Alginate: Formulation and in Vitro Evaluation of Antifungal Activity. Journal of Encapsulation and Adsorption Sciences, 3, 48-55.

[11]   Paques, J.P., van der Linden, E., van Rijn, C.J. and Sagis, L.M. (2014) Preparation Methods of Alginate Nanoparticles. Advances in Colloid and Interface Science, 209, 163-171.

[12]   Belyaeva, E., Valle, D.D., Neufeld, R.J. and Poncelet, D. (2004) New Approach to the Formulation of Hydrogel Beads Byemulsi & Cation/Thermal Gelation Using a Static Mixer. Chemical Engineering Science, 59, 2913-2920.

[13]   Wang, A., Tao, C., Cui, Y., Duan, L., Yang, Y. and Li, J. (2009) Assembly of Environmental Sensitive Microcapsules of PNIPAAm and Alginate Acidand Their Application in Drug Release. Journal of Colloid and Interface Science, 332, 271-279.

[14]   Katoh, K., Yoshimura, H. and Fujita, H. (2005) Preparation of Porous Matrices of Natural Polymer Using Microcapsules. Aichiken Sangyou Gijutsu Kenkyuujo kenkyuu houkoku, 4, 200-203.

[15]   Tian, K., Xie, C. and Xia, X. (2013) Chitosan/Alginate Multilayer film for Controlled Release of IDM on Cu/LDPE Composite Intrauterine Devices. Colloids and Surfaces B: Biointerfaces, 109, 82-89.

[16]   Su, J.F., Wang, S.B., Zhang, Y.Y. and Huang, Z. (2011) Physicochemical Properties and Mechanical Characters of Methanol-Modified Melamine-Formaldehyde (MMF) Shell MicroPCMS Containing Paraffin. Colloid and Polymer Science, 289, 111-119.

[17]   Yuan, Y., Zhang, N., Tao, W., Cao, X. and He, Y. (2014) Fatty Acids as Phase Change Materials: A Review. Renewable and Sustainable Energy, 29, 482-498.

[18]   Yang, Z., Peng, Z., Li, J., Li, S., Kong, L., Li, P. and Wang, Q. (2014) Development and Evaluation of Novel Flavour Microcapsules Containing Vanilla Oil Using Complex Coacervation Approach. Food Chemistry, 145, 272-277.

[19]   Chang, C.P., Leung, T.K., Lin, S.M. and Hsu, C.C. (2006) Release Properties on Gelatin-Gum Arabic Microcapsules Containing Camphor Oil with Added Polystyrene. Colloids and Surfaces B: Biointerfaces, 50, 136-140.

[20]   Soottitantawat, A., Bigeard, F., Yoshii, H., Furuta, T., Ohkawara, M. and Linko, P. (2005) Influence of Emulsion and Powder Size on the Stability Ofencapsulated d-Limonene by Spray Drying. Innovative Food Science and Emerging Technologies, 6, 107-114.

[21]   Polavarapu, S., Oliver, C.M., Ajlouni, S. and Augustin, M.A. (2012) Impact of Extra Virgin Olive Oil and Ethylene-diaminetetraacetic Acid (EDTA) on the Oxidative Stability of Fish Oil Emulsions and Spray-Dried Microcapsules Stabilized by Sugar Beet Pectin. Journal of Agricultural and Food Chemistry, 60, 444-450.

[22]   Gharsallaoui, A., Saurel, R., Chambin, O., Cases, E., Voilley, A. and Cayot, P. (2010) Utilisation of Pectin Coating to Enhance Spray-Dry Stability of Pea Protein-Stabilised Oil-in-Water Emulsions. Food Chemistry, 122, 447-454.

[23]   Taguchi, Y., Ono, F. and Tanaka, M. (2013) Preparation of Microcapsules Containing β-Carotene with Thermo Sensitive Curdlan by Utilizing Reverse Dispersion. Pharmaceutic, 5, 609-620.