CRCM  Vol.3 No.7 , July 2014
A Rare Case of Synchronous Bilateral Pleomorphic Adenoma of the Parotid Gland
Abstract: Multiple parotid gland tumors are unusual. Warthin’s tumor is the most represented neoplasm in this condition. We present a case of bilateral synchronous pleomorphic adenoma affecting the parotid glands in a 28-year-old woman. Clinically, the lesions were similar to solitary pleomorphic adenoma. Both lesions were diagnosed by fine-needle aspiration cytology. A total parotidectomy for left tumor and surgical enucleation for the right tumor, respectively, were performed with no facial nerves injury. A review of the pertinent literature is included.
Cite this paper: Filippo, R. , Angelo, P. , Flavia, O. , Annalisa, P. , Teresa, A. and Massimo, M. (2014) A Rare Case of Synchronous Bilateral Pleomorphic Adenoma of the Parotid Gland. Case Reports in Clinical Medicine, 3, 387-391. doi: 10.4236/crcm.2014.37086.

[1]   Silva, S.J., Costa Jr., G.T., Brant Filho, A.C., et al. (2006) Metachronous Bilateral Pleomorphic Adenoma of the Parotid Gland. Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology, 101, 333-338.

[2]   Yu, G.Y., Ma, D.Q., Zhang, Y., et al. (2004) Multiple Primary Tumours of the Parotid Gland. International Journal of Oral and Maxillofacial Surgery, 33, 531-534.

[3]   Seifert, G. and Donath, K. (1996) Multiple Tumours of the Salivary Glands: Terminology and Nomenclature. European Journal of Cancer Part B: Oral Oncology, 32B, 3-7.

[4]   Ethunandan, M., Pratt, C.A. and Macpherson, D.W. (2002) Changing Frequency of Parotid Neoplasms-Analysis of 560 Tumours Treated in a District General Hospital. Annals of the Royal College of Surgeons of England, 84, 1-6.

[5]   Turnbull, A.D. and Frazell, E.L. (1969) Multiple Tumors of the Major Salivary Glands. The American Journal of Surgery, 118, 787-789.

[6]   Ethunandan, M., Pratt, C.A., Morrison, A., et al. (2006) Multiple Synchronous and Metachronous Neoplasms of the Parotid Gland: The Chichester Experience. British Journal of Oral and Maxillofacial Surgery, 44, 397-401.

[7]   Nagler, R.M. and Laufer, D. (1999) Synchronous Pleomorphic Adenomas of the Major Salivary Glands: A Case Report. Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology, 87, 735-737.

[8]   Takeichi, N., Hirose, F., Yamamoto, H., et al. (1983) Salivary Gland Tumors in Atomic Bomb Survivors, Hiroshima, Japan. II. Pathologic Study and Supplementary Epidemiologic Observations. Cancer, 52, 377-385.<377::AID-CNCR2820520232>3.0.CO;2-9

[9]   Tanaka, S., Tabuchi, K., Oikawa, K., et al. (2007) Synchronous Unilateral Parotid Gland Neoplasms of Three Different Histological Types. Auris Nasus Larynx, 34, 263-266.

[10]   Keldahl, M.L., Zarif, A. and Gattuso, P. (2004) Bilateral Synchronous Pleomorphic Adenoma Diagnosed by Fine Needle Aspiration. Diagnostic Cytopathology, 30, 356-358.

[11]   Kakimoto, N., Gamoh, S., Tamaki, J., et al. (2009) CT and MR Images of Pleomorphic Adenoma in Major and Minor Salivary Glands. European Journal of Radiology, 69, 464-472.

[12]   Christe, A., Waldherr, C., Hallett, R., et al. (2011) MR Imaging of Parotid Tumors: Typical Lesion Characteristics in MR Imaging Improve Discrimination between Benign and Malignant Disease. American Journal of Neuroradiology, 32, 1202-1207.

[13]   Ghosh, S., Panarese, A., Bull, P.D., et al. (2003) Marginally Excised Parotid Pleomorphic Salivary Adenomas: Risk Factors for Recurrence and Management. A 12.5-Year Mean Follow-Up Study Histologically Marginal Excisions. Clinical Otolaryngology Allied Sciences, 28, 262-266.

[14]   Brill, A.H. and Fitz-Hugh, G.S. (1975) Bilateral Mixed Tumors of the Parotid Gland. Archives of Otolaryngology, 101, 751-753.