bone plasmacytoma [SBP] is a localised variant of plasma cell tumor which
commonly affects the axial skeleton but rarely found in the maxillofacial
region. We hereby report an unusual case of solitary plasmacytoma of the right
zygomatic bone in a 70-year-old Nigerian. Case Report: The patient presented
with a painless right zygomatic swelling of 2 years duration. Examination
showed that the swelling was of mixed consistency [mostly bony but firm in some
areas] and it measured about 8 × 8 cm. Radiographic
examination revealed an osteolytic lesion over the right zygoma with
involvement of the apex and lateral wall of the antrum. An initial working diagnosis of ossifying fibroma was made
and the patient was scheduled for surgery. Histological staining with H & E
and immunohistochemistry of the surgical specimen however confirmed a diagnosis
of SBP. Serum monoclonal protein and Bence Jones proteinuria was negative
throughout the follow up period. Conclusion: SBP of the maxillofacial region is
amenable to surgery combined with postoperative radiotherapy. However,
prognosis can be worsened with tumor recurrence or dissemination into MM. Thus
patients with SBP must be closely followed up after treatment so that immediate
therapeutic steps can be taken if recurrence or systemic dissemination is
Cite this paper
Obimakinde, O. , Taiwo, O. , Lawal, A. , Adisa, A. , Okoje, V. and Arotiba, J. (2014) Solitary Plasmacytoma of the Zygoma in a 70-Year-Old Nigerian: A Case Report and Review of Literature. International Journal of Otolaryngology and Head & Neck Surgery
, 195-199. doi: 10.4236/ijohns.2014.34036
 Rao, K., Priya, N.S., Umadevi, H.S., Smitha, T., Reshma, V. and Grace, S.A. (2011) Bone Plasmacytoma of the Maxilla: A Rare Case Report. International Journal of Clinical Dentistry, 2, 37-40.
 Gupta, A. and Bansal, P. (2011) Mandibular Swellimg—Can It Be Multiple Myeloma? Indian Journal of Dental Sciences, 3, 25-27.
 Dimopolous, M.A., Goldstein, J., Fuller, L., Delasalle, K. and Alexanian, R. (1992) Curability of Solitary Plasmacytoma of Bone. Journal of Clinical Oncology, 10, 587-590.
 Serena, M. and Pierpaolo, D.M. (2010) Solitary Plasmacytoma of the Jaw. Journal of Blood Medicine, 1, 33-38.
 Epstein, J.B., Voss, N.J. and Stenenson-Moore, P. (1984) Maxillofacial Manifestations of Multiple Myeloma. An Unusual Case and Review of Literature. Oral Surgery Oral Medicine Oral Pathology, 57, 267-271.
 Das, S.K., Saha, S., Bhowmic, A.K., Mukhejee, S. and Banerjee, S. (2004) Maxillary Swelling—A Rare Presentation of Solitary Plasmacytoma. Indian Journal of Otolaryngology and Head & Neck Surgery, 56, 213-215.
 Agostini, T., Sacco, R., Bertolai, R., Acocella, A. and Lazzeri, D. (2011) Solitary Plasmacytoma of the Jaw. Journal of Craniofacial Surgery, 22, 2-10. http://dx.doi.org/10.1097/SCS.0b013e31822ec79a
 Rodriguez-Caballero, B., Sanchez-Santolino, S., Garcia-Montesinos-Perea, B., Garcia-Reija, M.F., Gomez-Roman, J. and Saiz-Bustillo, R. (2011) Mandibular Solitary Plasmocytoma of the Jaw: A Case Report. Medicina Oral Patologia Oral y Cirugia Bucal, 16, 647-650. http://dx.doi.org/10.4317/medoral.16952
 Dimopolous, M.A., Moulopoulos, L.A., Maniatis, A. and Alexanian, R. (2000) Solitary Plasmacytoma of Bone and Asymptomatic Multiple Myeloma. Blood, 96, 2037-2044.
 Chang, M.Y., Shih, L.Y., Dunn, P., Leung, W.M. and Chen, W.J. (1994) Solitary Plasmacytoma of Bone. Journal of the Formosan Medical Association, 93, 307-402.
 Anil, S. (2007) Solitary Plasmacytoma of the Maxilla—A Case Report and Review of the Literature. General Dentistry Journal, 55, 39-43.
 Miller, F.R., Lavertu, P., Wanamaker, J.R., Bonafede, J. and Wood, B.G. (1998) Plasmacytomas of the Head and Neck. Otolaryngology—Head and Neck Surgery, 119, 614-618. http://dx.doi.org/10.1016/S0194-5998(98)70021-X
 Mustoe, T.A., Fried, M.P., Goodman, M.L., Kelly, J.H. and Strome, M. (1984) Osteosclerotic Plasmacytoma of the Maxillary Bone [Orbital Floor]. Journal of Laryngology and Otology, 98, 929-938. http://dx.doi.org/10.1017/S0022215100147735
 Canger, E.M. and Celenk, P. (2007) Mandibular Involvement of Solitary Plasmacytoma: A Case Report. Medicina Oral Patologia Oral y Cirugia Bucal, 12, 7-9.