TGW is an important agronomic trait that influences the yield and milling quality of wheat. In this paper, after having investigated the phenotype of TGW from 114 ITMI recombinant inbred genealogies in 4 years in Qaidam Basin, a typical plateau oasis agricultural area, and having combined 1410 molecular markers, 7 major QTL loci of the thousand gain weight were screened out with the aid of QTL network software. These loci included qTgw1B (42.6 cm), qTgw2A(77.9 cm), qTgw2D1 (25.4 cm), qTgw2D2 (51.8 cm), qTgw6A1 (56.1 cm), qTgw6A2 (62.2 cm) and qTgw7A(75.7 cm) with their genetic contribution rates between 3.29% - 19.36%. There were two epistatic effect loci2A-2D and2A-6B with their genetic contribution rates as 2.3% and 5.3% respectively. The quantitative genetic locus positioning of thousand hexaploid wheat grain weight in Qaidam Basin can assist us in better understanding the genetic regulatory network formed by TGW, and can also provide a theoretical basis for improving thousand wheat grain weight in this ecological area.
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