OJMM  Vol.4 No.2 , June 2014
Analysis of the Tropism and Anti-Bacterial Potential of a Type of Clay
ABSTRACT
Natural clays have been used by man in infections of bacterial etiology, since the first historical registers. Our attention turned to a red-colored clay, known in the northeast of Brazil as “barro de lou&#231a” (dish clay). These clays and other natural earth materials seem interesting to us, as the blockage of the liberation of toxins or inactivation, may be related to the interruption of infection cycles in the skin and mucous membranes. The adsorptive and absorptive properties of the mineral clays are well documented in the cure process of skin and gastrointestinal diseases. Susceptibility and bacterial tropism tests were carried out. The results were analyzed and interpreted according to the conventional microbiological protocol. The bacterial strains, Staphylococcus aureus, Escherichia coli e Pseudomonas aeruginosa, did not present a susceptibility profile to an isotonic solution of clay, but there was an increase of the bacterial tropism as the concentration of the isotonic solution was increased, being the minimal observed concentration of 100 mg/mL. Our aim is to document a type of red clay from the northeast of Brazil with possible attraction properties (Tropism) to bacteria and their toxins.

Cite this paper
Medeiros, C. , Sá, E. , Oliveira, J. , Magalhães, L. , Filho, G. and Pessôa, H. (2014) Analysis of the Tropism and Anti-Bacterial Potential of a Type of Clay. Open Journal of Medical Microbiology, 4, 140-145. doi: 10.4236/ojmm.2014.42016.
References
[1]   Williams, L.B., Holland, M., Eberl, D.D., Brunet, T. and Brunet de Courssou, L. (2004) Killer Clays! Natural Antibacterial Clay Minerals. Mineral Society Bulletin, London, 139, 3-8.
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3126108

[2]   Carretero, M.I. and Lagaly, G. (2007) Clays and Health: An Introduction. Applied Clay Science, 36, 1-3.
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2895274
http://dx.doi.org/10.1016/j.clay.2006.09.001


[3]   Zague, V., Santos, D.A., Baby, A.R. and Velasco, M.V.R. (2007) Argilas: Natureza das máscaras faciais. Cosmetics & Toiletries, 19, 64.

[4]   Gomes, C.S.F. and Silva, J.B.P. (2007) Minerals and Clay Minerals in Medical Geology. Applied Clay Science, 36, 4- 21.
http://dx.doi.org/10.1016/j.clay.2006.08.006

[5]   Amorim, L.V., Viana, J.D., Farias, K.V., Barbosa, M.I.R. and Ferreira, H.C. (2006) Estudo comparativo entre varie- dades de argilas bentoníticas de Boa Vista, Paraíba. Revista Matéria, 11, 30-40.
http://www.scielo.br/pdf/rmat/v11n1/a06v11n1.pdf

[6]   Sozer, N. and Kokini, J.L. (2009) Review: Nanotechnology and Its Applications in the Food Sector. Trends in Biotechnology, 27, 82-89.
http://dx.doi.org/10.1016/j.tibtech.2008.10.010

[7]   Williams, L.B. and Hayel, S.E. (2010) Evaluation of the Medicinal Use of Clay Minerals as Antibacterial Agents. NIH Public, 52, 745-770.

[8]   Fernades, P. (2006) Antibacterial Discovery and Development—The Failure of Success? Nature Biotechnology, 24, 1497-1503.
http://dx.doi.org/10.1038/nbt1206-1497

[9]   Martinez, J.L. (2009) The Role of Natural Environments in the Evolution of Resistance Traits in Pathogenic Bacteria. Proceedings of the Royal Society B: Biological Sciences, 276, 2521-2530.
http://dx.doi.org/10.1098/rspb.2009.0320

[10]   Williams, L.B., Metge, D.W., Eberl, D.D., Harvey, R.H., Turner, A.G., Prapaipong, P. and Poret-Peterson, A.T. (2011) What Makes a Natural Clay Antibacterial? National Institutes of Health, 45, 3768-3773.
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3126108

[11]   Williams, L.B., Haydel, S.E., Geise, R.F., Eberl, D.D. (2008) Chemical and Mineralogical Characteristics of French Green Clays Used for Healing. Clays Clay Minerals, 56, 437-452.
http://www.ncbi.nlm.nih.gov/pubmed/19079803

[12]   Cunningham, T.B., Koehl, J.L., Summers, J.S. and Haydel, S.E. (2010) pH-Dependent Metal Ion Toxicity Influences of the Antibacterial Activity of Two Natural Mineral Mixtures.
http://www.ncbi.nlm.nih.gov/pubmed/20209160

[13]   Haydel, S.E., Remineh, C.M. and Williams, L.B. (2008) Broad-Spectrum in Vitro Antibacterial Activities of Clay Mi- nerals against Anti Biotic-Susceptible and Antibiotic-Resistant Bacterial Pathogens. Journal of Antimicrobial Chemotherapy, in Press.

[14]   Jackson, M.L. (1979) Soil Chemical Analysis Advanced Course. 2nd Edition.

[15]   Tovar-Sanchez, A., Sanudo-Wilhelmy, S.A., Garcia-Vargas, M., Weaver, R.S., Popels, L.C. and Hutchins, D.A. (2003) A Trace Metal Clean Reagent to Remove Surface-Bound Iron from Marine Phytoplankton. Marine Chemistry, 82, 91- 99.
http://dx.doi.org/10.1016/S0304-4203(03)00054-9

[16]   Vogel, C. and Fisher, N.S. (2010) Metal Accumulation by Heterotrphic Marine Bacterioplankton. Limnology and Oce- anography, 55, 519-528.
http://dx.doi.org/10.4319/lo.2009.55.2.0519

[17]   Nolte, W.A. (1982) Oral Microbiology. 4. Mosby, London. 3-37.
http://www.bibliotecadigital.unicamp.br/document/?down=000788730

[18]   Menezes, R.R., Souto, P.M., Santana, L.N.L., Neves, G.A., Kiminami, R.H.G.A. and Ferreira, H.C. (2009) Argilas bentoníticas de Cubati, Paraíba, Brasil: Caracterizacao físico-mineralógica. Ceramica, 55, 163-169.
http://dx.doi.org/10.1590/S0366-69132009000200008

[19]   Beiler, R.C.G. (2012) Kinetic Study of Incorporation of Zinc in Bentonite: Development of Antimicrobial Material. 77F. Dissertation (Postgraduate Program in Chemical Engineering), Federal University of Santa Catarina, Florianópolis.

[20]   Silva, M.L.G. (2011) Preparation and Characterization of Piauí paligorsquita clay (attapulgite) organophilizated for Use in Cosmetic formutions. 106f. Dissertation (Postgraduate Diploma in Pharmaceutical Sciences), Federal University of Piauí, Teresina.

[21]   Souza, V.M. and Antunes, J.D. (2008) Dermatological Active: Guide Dermatological Assets Used in Pharmacy Compounding for Physicians and Pharmacists. Pharmabooks, Sao Paulo.

 
 
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