The following article has been retracted due to the investigation of complaints received against it. The Editorial Board found that there are conflicts of interests between the authors and their organization. The scientific community takes a very strong view on this matter, and the American Journal of Analytical Chemistry treats all unethical behavior seriously. This paper published in Vol. 5 No. 9 589-597, 2014 has been removed from this site.
Title: Determination of Sibutramine and Its N-Desmethyl Metabolites in Human Plasma Using HPLC Coupled with Tandem MassAuthor: Mohammad Al-Bayyari
 Heal, D.J., Aspley, S., Jackson, H.C., Martin, K.F. and Cheetham, S.C. (1998) Sibutramine: A Novel Anti-Obesity Drug. A Review of the Pharmacological Evidence to Differentiate It from d-Amphetamine and d-Fenfluramine. International Journal of Obesity, 22, S18-S28.
 Luscombe, G.P., Hopcroft, R.H., Thomas, P.C. and Buckett, W.R. (1989) The Contribution of Metabolites to the Rapid and Potent Down-Regulation of Rat Cortical Beta-Adrenoceptors by the Putative Antidepressant Sibutramine Hydrochloride. Neuropharmacology, 28, 129-134.
 Balcioglu, A. and Wurtman, R.J. (2000) Sibutramine, a Serotonin Uptake Inhibitor, Increases Dopamine Concentrations in Rat Striatal and Hypothalamic Extracellular Fluid. Neuropharmacology, 39, 2352-2359.
 Gundlah, C., Martin, K.F., Heal, D.J., et al. (1997) In Vivo Criteria to Differentiate Monoamine Reuptake Inhibitors from Releasing Agents: Sibutramine Is a Reuptake Inhibitor. Journal of Pharmacology and Experimental Therapeutics, 283, 581-591.
 Jackson, H.C., Bearham, M.C., Hutchins, L.J., Mazurkiewicz, S.E., Needham, A.M. and Heal, D.J. (1997) Investigation of the Mechanisms Underlying the Hypophagic Effects of the 5-HT and Noradrenaline Reuptake Inhibitor, Sibutramine, in the Rat. British Journal of Pharmacology, 121, 1613-1618.
 Jackson, H.C., Needham, A.M., Hutchins, L.J., Mazurkiewicz, S.E. and Heal, D.J. (1997) Comparison of the Effects of Sibutramine and Other Monoamine Reuptake Inhibitors on Food Intake in the Rat. British Journal of Pharmacology, 121, 1758-1763.
 Connoley, I.P., Liu, Y.L., Frost, I., Reckless, I.P., Heal, D.J. and Stock, M.J. (1999) Thermogenic Effects of Sibutramine and Its Metabolites. British Journal of Pharmacology, 126, 1487-1495.
 Hind, I.D., Mangham, J.E., Ghani, S.P., Haddock, R.E., Garratt, C.J. and Jones, R.W. (1999) Sibutramine Pharmacokinetics in Young and Elderly Healthy Subjects. European Journal of Clinical Pharmacology, 54, 847-849.
 Radhakrishna, T., Narayana, C.L., Rao, D.S., Vyas, K. and Reddy, G.O. (2000) LC Method for the Determination of Assay and Purity of Sibutramine Hydrochloride and Its Enantiomers by Chiral Chromatography. Journal of Pharmaceutical and Biomedical Analysis, 22, 627-639.