APD  Vol.3 No.2 , May 2014
Medical Food to Stop the Progression of Parkinson’s Disease
Author(s) Don McCammon*
ABSTRACT

No progress has been made in the development of drugs to stop the progression of Parkinson’s Disease. Here the author has presented a novel approach to stopping the disease using a dietary supplement primarily composed of Mannitol. In vivo animal studies have shown that Mannitol was able to break up alpha-synuclein clusters and restore functioning in transgenic drosophila and mice. The author, who has Parkinson’s, used himself as a subject and was able to achieve similar results.

KEYWORDS
Mannitol

Cite this paper
McCammon, D. (2014) Medical Food to Stop the Progression of Parkinson’s Disease. Advances in Parkinson's Disease, 3, 10-13. doi: 10.4236/apd.2014.32003.
References
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[2]   Bartels, T., Choi, J.G. and Selkoe, D.J. (2011) A-Synuclein Occurs Physiologically as a Helically Folded Tetramer That Resists Aggregation. Nature, 477, 107-110. http://dx.doi.org/10.1038/nature10324

[3]   Orenstein, S.J., Kuo, S.H., Tasset, L., Loga, H., et al. (2013) Interplay of LRRK@2 with Chaperone-mEdiated Autophagy. Nature Neuroscience, 394-406. http://dx.doi.org/10.1038/nn.3350

[4]   American Friends of Tel Aviv University. Artificial Sweetener a Potential Treatment for Parkinson’s Disease. ScienceDaily. ScienceDaily, 17 June 2013.
www.sciencedaily.com/releases/2013/06/130617122401.htm

[5]   Shaltiel-Karyo, R., Frenkel-Pinter, M., Rockenstein, E., Patrick, C., Levy-Sakin, M., Schiller, A., Egoz-Matia, N., Masliah, E., Segal, D. and Gazit. E. (2013) A Blood-Brain Barrier (BBB) Disrupter Is Also a Potent-Synuclein (-syn) Aggregation Inhibitor: A NOVEL DUAL MECHANISM OF MANNITOL FOR THE TREATMENT OF PARKINSON DISEASE (PD). Journal of Biological Chemistry, 288, 17579.
http://dx.doi.org/10.1074/jbc.M112.434787

 
 
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