SS  Vol.5 No.5 , May 2014
Adenocarcinoma of the Appendix in Young Men with Acute Appendicitis
Abstract: Intoduction: The adenocarcinomas of the appendix are rare tumors of the gastrointestinal truct that often reveal no clear clinical symptoms and are not diagnosed in time. In this study, we analyze a rare case of an incidentally discovered adenocarcinoma of the appendix after appendicectomy. Case presentation: A Greek male patient of 37 years old patient presented to our hospital with signs of acute appendicitis and peritonitis. He underwent appendicectomy as therapeutic treatment. Post operational histological examination revealed in situ carcinoma of the appendix without high hematological tumor markers or visible metastasis in CT scan analysis. We decided to proceed to right hemicolectomy. The patient was discharged without complications and without displaying other symptoms in a monitoring interval of two months after surgery. Conclusion: Adenocarcinomas of the appendix are generally difficult to detect in the early stage leading to significant morbidity and mortality rates. Therefore, it is necessary to execute a very careful histopathological examination and perform a detailed intraperitoneal cleaning during operation, so that any indications of appendix adenocarcinomas in cases of appendectomy won’t be missed or misjudged.
Cite this paper: Alexiou, K. , Ioannidis, A. , Drikos, I. , Karanikas, I. , Fotopoulos, A. , Chorti, M. and Economou, N. (2014) Adenocarcinoma of the Appendix in Young Men with Acute Appendicitis. Surgical Science, 5, 206-209. doi: 10.4236/ss.2014.55035.

[1]   McCusker, M., Coté, T., Clegg, L. and Sobin, L. (2002) Primary Malignant Neoplasms of the Appendix: A Population Based Study from the Surveillance, Epidemiology and Endresults Program, 1973-1998. Cancer, 94, 3307-3312.

[2]   Connor, S., Hanna, G. and Frizelle, F. (1998) Retrospective Clinicopathologic Analysis of Appendiceal Tumors from 7970 Appendectomies. Diseases of the Colon and Rectum, 41, 75-80.

[3]   Ruoff, C., Hanna, L., Zhi, W., Shahzad, G., Gotlieb, V. and Saif, M. (2011) Cancers of the Appendix: Review of the Literatures. International Scholarly Research Network (ISRN) Oncology, 2011, Article ID: 728579.

[4]   O’Donnell, M., Badger, S., Beattie, G., Carson, J. and Garstin, W. (2007) Malignant Neoplasms of the Appendix. International Journal of Colorectal Disease, 22, 1239-1248.

[5]   Nilecki, S., Wolff, B., Schlinkert, R. and Sarr, M. (1994) The Natural History of Surgically Treated Primary Adenocarcinoma of the Appendix. Annals of Surgery, 219, 51-57.

[6]   Murphy, E.M., Farquharson, S.M. and Moran, B.J. (2006) Management of an Unexpected Appendiceal Neoplasm. British Journal of Surgery, 93, 783-792.

[7]   Park, I., Yu, C., Kim, H. and Kim, J. (2004) Clinical Features and Prognostic Factors in Primary Adenocarcinoma of the Appendix. The Korean Journal of Gastroenterology, 43, 29-34.

[8]   Turaga, K., Pappas, S. and Gamblin, C. (2013) Right Hemicolectomy for Mucinous Adenocarcinoma of the Appendix: Just Right or Too Much? Annals of Surgical Oncology, 20, 1063-1067.

[9]   Swank, H., Eshuis, E., Ubbink, D. and Bemelman, W. (2011) Is Routine Histopathological Examination of Appendectomy Specimens Useful? A Systematic Review of the Literature. Colorectal Disease, 13, 1214-1221.

[10]   Trivedi, A., Levine, E.A. and Mishra, G. (2009) Adenocarcinoma of the Appendix Is Rarely Detected by Colonoscopy. Journal of Gastrointestinal Surgery, 13, 668-675.

[11]   Varisco, B., McAlvin, B., Dias, J. and Franga, D. (2004) Adenocarcinoid of the Appendix: Is Right Hemicolectomy Necessary? A Meta-Analysis of Retrospective Chart Reviews. The American Surgeon, 70, 593-599.

[12]   Smejkal, P., Pazdro, A., Smejkal, M., Pafko, P. and Frantlova, M. (2005) The Cystadenocarcinoma of the Appendix. Rozhledy v Chirurgii, 84, 33-36.

[13]   Vaira, M., Scuderi, S., Costamagna, B.R., Aghemo, B., Mioli, P.R. and De Simone, M. (2001) Cytoreductive Surgery and Intraperitoneal Hyperthermic Antiblastic Therapy (HAPP) in Peritoneal Carcinomatosis. Minerva Chirurgica, 57, 597-605.

[14]   Mori, N., Noma, M., Hara, T., Yamaguchi, S., Shibata, K., Ishii, T. and Adachi, S. (2002) A Case of Mucinous Cystadenocarcinoma of the Appendix Penetrating the Urinary Bladder. Hinyokika Kiyo, 48, 351-354.

[15]   Katsuno, G., Kagawa, S., Kokudo, Y., Muraoka, A., Tatemoto, A., Sone, Y., Tsumura, M., Tsuruno, M. and Mizobuchi, K. (2005) Ureteral Metastasis from Appendiceal Cancer: Report of a Case. Surgery Today, 35, 168-171.

[16]   Kamran, A., Hoque, R., El-Tawil, S., Khan, M. and George, M. (2008) Adenocarcinoma of the Appendix Presenting as Bilateral Ureteric Obstruction. World Journal of Surgical Oncology, 6, 23-28.