A Case Report of Orf Disease in a Greek Island: Diagnostic Tests or Interventions Are Not Necessary

M.  Lalountas; A.  Kriari; C.  Asteriou; I.  Tornikidis; P.  Lazaridis

doi:10.4236/mri.2014.32008

M. Lalountas, A. Kriari, C. Asteriou, I. Tornikidis, P. Lazaridis

Abstract: The Orf disease, also known as contagious ecthyma, is a zoonotic infection caused by a dermatotropic parapoxvirus that commonly infects small ruminants such as sheep and goats. It is transmitted to humans through contact with an infected animal or fomites. Human infection typically is associated with occupational animal contact. We recently treated a healthy 41-year-old woman who presented a hangnail lesion on the middle finger of her right hand. The lesion was hard cauliflower-like mass, granulomatous and painful. Surgical debridement and biopsy were performed for further investigation. The Orf disease is usually self-limiting and resolves in 6 - 10 weeks, but complications may occur. The diagnosis may be confirmed by electron microscopy, conventional histopathology or by isolation of the virus by PCR. Early clinical recognition and knowledge of this benign viral condition are vital to avoid unnecessary surgical intervention.

Keywords: Orf Disease, Parapoxvirus, Contagious Ecthyma, Hand, Treatment

Cite this paper: Lalountas, M. , Kriari, A. , Asteriou, C. , Tornikidis, I. and Lazaridis, P. (2014) A Case Report of Orf Disease in a Greek Island: Diagnostic Tests or Interventions Are Not Necessary. Modern Research in Inflammation, 3, 67-69. doi: 10.4236/mri.2014.32008.

References

[1] Centers for Disease Control and Prevention (CDC) (2012) Human Orf Virus Infection from Household Exposures-United States, 2009-2011. MMWR Morbidity and Mortality Weekly Report, 61, 245-248.

[2] Mourtada, I., Le Tourneur, M., Chevrant-Breton, J. and Le Gall, F. (2000) Human Orf and Erythema Multiforme. Annals of Dermatology of Venereology, 127, 397-399.

[3] Frandsen, J., Enslow, M. and Bowen, A.R. (2011) Orfparapoxvirus Infection from a Cat Scratch. Dermatology Online Journal, 17, 9.

[4] Centers for Disease Control and Prevention (CDC) (2006) Orf Virus Infection in Humans-New York, Illinois, California, and Tennessee, 2004-2005. MMWR Morbidity and Mortality Weekly Report, 55, 65-68.

[5] Engel, H., Marot, L., Zech, F. and Thys, F. (2010) The “Orf” Virus: Focus and Review of the Literature. Revue Medicale de Liege, 65, 691-695.

[6] Uzel, M., Sasmaz, S., Bakaris, S., Cetinus, E., Bilgic, E., Karaoguz, A., Ozkul, A. and Arican, O. (2005) A Viral Infection of the Hand Commonly Seen after the Feast of Sacrifice: Human Orf (Orf of the Hand). Epidemiology & Infection, 133, 653-657. http://dx.doi.org/10.1017/S0950268805003778

[7] Lederman, E.R., Green, G.M., DeGroot, H.E., Dahl, P., Goldman, E., Greer, P.W., Li, Y., Zhao, H., Paddock, C.D. and Damon, I.K. (2007) Progressive ORF Virus Infection in a Patient with Lymphoma: Successful Treatment Using Imiquimod. Clinical Infectious Diseases, 44, 100-103. http://dx.doi.org/ 10.1086/517509

[8] Taieb, A., Guillot, M., Carlotti, D. and Maleville, J. (1998) Orf and Pregnancy. International Journal of Dermatology, 27, 31-33. http://dx.doi.org/10.1111/j.1365-4362.1988.tb02331.x

[9] Erbagci, Z., Erbagci, I. and Almila Tuncel, A. (2005) Rapid Improvement of Human Orf (Ecthyma Contagiosum) with Topical Imiquimod Cream: Report of Four Complicated Cases. Journal of Dermatological Treatment, 16, 353-356. http://dx.doi.org/10.1080/09546630500375734

[10] Lederman, E.R., Austin, C., Trevino, I., Reynolds, M.G., Swanson, H., Cherry, B., Ragsdale, J., Dunn, J., Meidl, S., Zhao, H., Li, Y., Pue, H. and Damon, I.K. (2007) ORF Virus Infection in Children: Clinical Characteristics, Transmission, Diagnostic Methods, and Future Therapeutics. The Pediatric Infectious Disease Journal, 26, 740-744. http://dx.doi.org/10.1097/INF.0b013e31806211bf

[11] Khaled, A., Robbana, F., Hammami, H., Kharfi, M., El Fekih, N., Fazaa, B. and Kamoun, M.R. (2009) Orf of the Hand. Tunis Medicine, 87, 352-353.

[12] Hosamani, M., Scagliarini, A., Bhanuprakash, V., McInnes, C.J. and Singh, R.K. (2009) Orf: An Update on Current Research and Future Perspectives. Expert Review of Anti-Infective Therapy, 7, 879-893. http://dx.doi.org/10.1586/eri.09.64