ODEM  Vol.2 No.2 , May 2014
Pesticide Biomonitoring in Florida Agricultural Workers
Abstract: This descriptive study evaluates the blood serum levels of relevant pesticides in fern/ornamental and tomato agricultural workers in central and south Florida whose work activity is related to pesticide application or crop maintenance. The objectives of this study are to broadly evaluate pesticide absorption in agricultural workers, assess personal protective equipment (PPE) use and their potential relevance to pesticide absorption, and to evaluate the feasibility of using primary biomonitoring as a method of exposure assessment for long-term epidemiological investigations. Three rounds of sampling were conducted where 41 subjects provided serum samples analyzed for individual pesticides and responded to a survey regarding PPE use. Serum samples yielded quantifiable detections of DDE, Methiocarb, Malathion, Chlorpyrifos, and Endosulfan in select subjects. The personal protective equipment survey did not demonstrate association with positive serum samples. These results demonstrate that the evaluated workers are effectively protected against exposures known to result in acute toxicity. Biomonitoring for parent compounds and primary metabolites may have limited utility in long-term epidemiological studies to evaluate chronic toxicity where workers are exposed to a great diversity of workplace chemicals (fern/or- namental workers) compared to agricultural sectors where workplace chemical diversity is more limited (tomato workers).
Cite this paper: Johnson, G. , Morris, S. , McCluskey, J. , Xu, P. and Harbison, R. (2014) Pesticide Biomonitoring in Florida Agricultural Workers. Occupational Diseases and Environmental Medicine, 2, 30-38. doi: 10.4236/odem.2014.22004.

[1]   Keifer, M. and Mahurin, R. (1997) Chronic Neurologic Effects of Pesticide Overexposure. Occupational Medicine, 12, 291-304.

[2]   He, F. (2000) Neurotoxic Effects of Insecticides—Current and Future Research: A Review. Neurotoxicology, 21, 829- 835.

[3]   London, L., Myers, J.E., Nell, V., Taylor, T. and Thompson, M.L. (1997) An Investigation into Neurologic and Neurobehavioral Effects of Long-Term Agrichemical Use among Deciduous Fruit Farm Workers in the Western Cape, South Africa. Environmental Research, 73, 132-145.

[4]   McConnell, R., Keifer, M. and Rosenstock, L. (1994) Elevated Quantitative Vibrotactile Threshold among Workers Previously Poisoned with Methamidophos and Other Organophosphate Pesticides. American Journal of Industrial Medicine, 25, 325-334.

[5]   Ohayo-Mitoko, G.J., Kromhout, H., Simwa, J.M., Boleij, J.S. and Heederik, D. (2000) Self Reported Symptoms and Inhibition of Acetylcholinesterase Activity among Kenyan Agricultural Workers. Occupational and Environmental Medicine, 57, 195-200.

[6]   Stokes, L., Stark, A., Marshall, E. and Narang, A. (1995) Neurotoxicity among Pesticide Applicators Exposed to Organophosphates. Occupational and Environmental Medicine, 52, 648-653.

[7]   Savage, E., Keefe, T.J., Mounce, L.M., Heaton, R.K., Lewis, J.A. and Burcar, P.J. (1988) Chronic Neurological Sequelae of Acute Organophosphate Pesticide Poisoning. Archives of Environmental Health, 43, 38-45.

[8]   Steenland, K., Jenkins, B., Ames, R.G., O’Malley, M., Chrislip, D. and Russo, J. (1994) Chronic Neurological Sequelae to Organophosphate Pesticide Poisoning. American Journal of Public Health, 84, 731-736.

[9]   Daniell, W., Barnhart, S., Demers, P., Costa, L.G., Eaton, D.L., Miller, M., et al. (1992) Neuropsychological Performance among Agricultural Pesticide Applicators. Environmental Research, 59, 217-228.

[10]   Gomes, J., Lloyd, O.L. and Revitt, D.M. (1999) The Influence of Personal Protection, Environmental Hygiene and Exposure to Pesticides on the Health of Immigrant Farm Workers in a Desert Country. International Archives of Occupational and Environmental Health, 72, 40-45.

[11]   Steenland, K., Dick, R.B., Howell, R.J., Chrislip, D.W., Hines, C.J., Reid, T.M., et al. (2000) Neurologic Function among Termiticide Applicators Exposed to Chlorpyrifos. Environmental Health Perspectives, 108, 293-300.

[12]   van Wendel de Joode, B., Wesseling, C., Kromhout, H., Monge, P., et al. (2001) Chronic Nervous-System Effects of Long-Term Occupational Exposure to DDT. Lancet, 357, 1014-1016.

[13]   Baldi, I., Filleul, L., Mohammed-Brahim, B., Fabrigoule, C., Dartigues, J., et al. (2001) Neuropsychologic Effects of Long-Term Exposure to Pesticides: Results from the French Phytoner Study. Environmental Health Perspectives, 109, 839-844.

[14]   Anger, W., Moody, L., Burg, J., Brightwell, W.S., Taylor, B.J., et al. (1986) Neurobehavioral Evaluation of Soil and Structural Fumigators Using Methyl Bromide and Sulfuryl Fluoride. Neurotoxicology, 7, 137-156.

[15]   Calvert, G.M., Mueller, C.A., Fajen, J.M., Chrislip, D.W., Russo, J., et al. (1998) Health Effects Associated with Sulfuryl Fluoride and Methyl Bromide Exposure among Structural Fumigation Workers. American Journal of Public Health, 88, 1774-1780.

[16]   Barr, D.B., Thomas, K., Curwin, B., Landsittel, D., Raymer, J., Lu, C., Donnelly, K.C. and Acquavella, J. (2006) Biomonitoring of Exposure in Farmworker Studies. Environmental Health Perspectives, 114, 936-942.

[17]   Coronado, G.D., Thompson, B., Strong, L., Griffith, W.C. and Islas, I. (2004) Agricultural Task and Exposure to Organophosphate Pesticides among Farmworkers. Environmental Health Perspectives, 112, 142-147.

[18]   Acquavella, J.F., Alexander, B.H., Mandel, J.S., Gustin, C., Baker, B., Chapman, P. and Bleeke, M. (2004) Glyphosate Biomonitoring for Farmers and Their Families: Results from the Farm Family Exposure Study. Environmental Health Perspectives, 112, 321-326.

[19]   Arbuckle, T.E., Burnett, R., Cole, D., Teschke, K., Dosemeci, M., Bancej, C. and Zhang, J. (2002) Predictors of Herbicide Exposure in Farm Applicators. International Archives of Occupational and Environmental Health, 75, 406-414.

[20]   Arcury, T.A., Quandt, S.A., Rao, P., Barr, D.B. and Hoppin, J.A. (2005) Organophosphate Pesticide Metabolite Levels among Farmworker Family Members in Western North Carolina: Case Comparisons. Human Organization, 64, 40-51.

[21]   Hines, C.J. and Deddens, J.A. (2001) Determinants of Chlorpyrifos Exposures and Urinary 3,5,6-Trichloro-2-pyridinol Levels among Termiticide Applicators. Annals of Occupational Hygiene, 45, 309-321.

[22]   CDC (2003) National Health and Nutrition Examination Survey. National Center for Health Statistics, Hyattsville.