here an extremely rare case of proliferative Brenner tumor with borderline
mucinous cystadenocarcinoma of the ovary, metastasizing to the pleura in a
75-year-old woman. Massive pleural effusion were present due to metastasis and pseudo-Meigs’
syndrome. The cytological findings from pleural effusion, ascites and tumor
imprint were similar, suggesting mucus-producing malignant tumors. After receiving
a thoracic drainage for pleural effusion, the patient underwent an exploratory
laparotomy to remove the left-ovarian tumor. Histopathological examination
revealed proliferative Brenner ovarian tumor with borderline mucinous cystadenocarcinoma,
and immunohistochemical examinations for the tumors, even mucus-rich tumor
cells were positive for CK 7 and negative for CK 20, suggesting the tumor
arising from transitional cells, not from mucus-producing ovarian surface
epithelial tumor cells. She underwent four courses of chemotherapy with
paclitaxel and carboplatin. The patient showed no signs of recurrence 16 months
after the surgery.
Cite this paper
Niwa, K. , Makino, H. , Yamaguchi, Y. , Mori, S. , Narikawa, N. and Tanaka, T. (2014) Proliferative Brenner Tumor with Borderline Mucinous Cystadenocarcinoma of the Ovary in a 75-Year-Old Woman. Open Journal of Pathology
, 48-53. doi: 10.4236/ojpathology.2014.42008
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