Choroid Plexus Carcinoma: A Rare Tumor in Adult

Chi-Man  Yip; Hui-Hwa  Tseng; Shu-Shong  Shu-Shong Hsu

doi:10.4236/ss.2014.54026

Chi-Man Yip^*, Hui-Hwa Tseng, Shu-Shong Shu-Shong Hsu

Abstract: Background: Choroid plexus carcinoma is a highly aggressive malignant, infrequent tumor with poor prognosis. About 80% of choroid plexus carcinoma occurs in children, but it is uncommon in adults. Because of the rarity of the choroid plexus carcinoma, there is no established treatment protocol for this malignancy. Case Description: A 21-year-old man with past medical history of asthma presented to us with the chief complaint of morning headache for one month. His brain magnetic resonance imaging (MRI) showed a mass in the trigone and occipital horn of the left lateral ventricle. He had undergone a left occipitoparietal craniotomy, posterior interhemispheric precuneus approach with grossly total removal of the tumor. The histology examination of the tumor proved to be choroid plexus carcinoma. This patient achieved a favorable outcome after having a grossly complete surgical resection followed by postoperative adjuvant radiotherapy and chemotherapy. Conclusions: Choroid plexus carcinoma is aggressive and is associated with dismal prognosis. The 5-year survival rates for choroid plexus carcinoma vary between 10% and 50%. Currently, there is no established treatment protocol for choroid plexus carcinoma. Complete resection of this malignant tumor is the primary goal of treatment since it allows best chance of survival and improves the overall prognosis.

Keywords: Choroid Plexus Carcinoma, Surgical Resection, Adjuvant Radiotherapy and Chemotherapy

Cite this paper: Yip, C. , Tseng, H. and Shu-Shong Hsu, S. (2014) Choroid Plexus Carcinoma: A Rare Tumor in Adult. Surgical Science, 5, 146-149. doi: 10.4236/ss.2014.54026.

References

[1] Bettegowda, C., Adogwa, O., Mehta, V., Chaichana, K.L., Weingart, J., Carson, B.S., Jallo, G.I. and Ahn, E.S. (2012) Treatment of Choroid Plexus Tumors: A 20-Year Single Institutional Experience. Journal of Neurosurgery: Pediatrics, 10, 398-405. http://dx.doi.org/10.3171/2012.8.PEDS12132

[2] Berger, C., Thiesse, P., Lellouch-Tubiana, A., Kalifa, C., Pierre-Kahn, A. and Bouffet, E. (1998) Choroid Plexus Carcinomas in Childhood: Clinical Features and Prognostic Factors. Neurosurgery, 42, 470-475.
http://dx.doi.org/10.1097/00006123-199803000-00006

[3] Fabi, A., Salesi, N., Di Cocco, B., Vidiri, A., Visca, P., Pace, A., Carapella, C., De Paula, U., Mirri, A. and Cognetti, F. (2005) Choroid Plexus Carcinoma in the Adult: Is There a Role for Chemotherapy? Journal of Experimental & Clinical Cancer Research, 24, 493-496.

[4] Gopal, P., Parker, J.R., Debski, R. and Parker, J.C. (2008) Choroid Plexus Carcinoma. Archives of Pathology & Laboratory Medicine, 132, 1350-1354.

[5] Wrede, B., Liu, P., Ater, J. and Wolff, J.E.A. (2005) Second Surgery and the Prognosis of Choroid Plexus Carcinoma—Results of a Meta-Analysis of Individual Cases. Anticancer Research, 25, 4429-4434.

[6] Wrede, B., Liu, P. and Wolff, J.E.A. (2007) Chemotherapy Improves the Survival of Patients with Choroid Plexus Carcinoma: A Meta-Analysis of Individual Cases with Choroid Plexus Tumors. Journal of Neuro-Oncology, 85, 345-351. http://dx.doi.org/10.1007/s11060-007-9428-x