Health  Vol.6 No.10 , April 2014
Age-Specific Clinical Features of Erectile Dysfunction
Abstract: Sexual health can be considered as a mirror of general health and, in turn, general health is a prerequisite for sexual heath. The aim of this study was to compare the different clinical features of erectile dysfunction (ED) in young and elderly males. From June 2011 to December 2011, 224 patients were included and divided into two groups. Elderly ED group consisted of 120 patients with ED and all were 61 - 90 years old, and young ED group consisted of 104 patients with ED and all were 21 - 45 years old. Questionnaires, physical examination, blood sample test, ultrasound monitor, time of achieving erection (TAE), intra-vaginal ejaculation latency time (IELT), ECG and penis-brachial blood pressure index (PBI) were investigated. There were significant differences between the two groups, regarding the top three complications, the body mass index (BMI), International Index of Erectile Function-5 (IIEF-5) scores, Self-rating Depression Scale (SDS) total scores, TAE, IELT and PBI. We concluded that clinical features of ED were age-specific, which will be helpful for treatment strategies and evaluation of the treatment efficacy.
Cite this paper: Cai, L. , Jiang, M. , Zeng, M. , Xing, W. , Wen, Y. and Zhang, B. (2014) Age-Specific Clinical Features of Erectile Dysfunction. Health, 6, 938-942. doi: 10.4236/health.2014.610118.

[1]   Masters, M.H. and Johnson, V. (1966) Human Sexual Response. Little Brown & Co., Boston.

[2]   Araujo, A.B., Mohr, B.A. and McKinlay, J.B. (2004) Changes in Sexual Function in Middle-Aged and Older Men: Longitudinal Data from the Massachusetts Male Aging Study. Journal of the American Geriatrics Society, 52, 1502-1509.

[3]   Yao, F., Liu, L., Zhang, Y., Huang, Y., Liu, D., Lin, H., Liu, Y., Fan, R., Li, C. and Deng, C. (2013) Erectile Dysfunction May Be the First Clinical Sign of Insulin Resistance and Endothelial Dysfunction in Young Men. Clinical Research in Cardiology, 102, 645-651.

[4]   Traish, A.M. and Galoosian, A. (2013) Androgens Modulate Endothelial Function and Endothelial Progenitor Cells in Erectile Physiology. Korean Journal of Urology, 54, 721-731.

[5]   Aversa, A., Bruzziches, R., Francomano, D., Natali, M., Gareri, P. and Spera, G. (2010) Endothelial Dysfunction and Erectile Dysfunction in the Aging Man. International Journal of Urology, 17, 38-47.

[6]   Hamed, S., Brenner, B. and Roguin, A.(2011) Nitric Oxide: A Key Factor behind the Dysfunctionality of Endothelial Progenitor Cells in Diabetes Mellitus Type-2. Cardiovasc Research, 91, 9-15.

[7]   Haas, C.A., Seftel, A.D., Razmjouei, K., Ganz, M.B., Hampel, N. and Ferguson, K. (1998) Erectile Dysfunction in Aging: Upregulation of Endothelial Nitric Oxide Synthase. Urology, 51, 516-522.

[8]   McMahon, C.G., Althof, S.E., Waldinger, M.D., et al. (2008) An Evidence-Based Definition of Lifelong Premature Ejaculation: Report of the International Society for Sexual Medicine (ISSM) ad hoc Committee for the Definition of Premature Ejaculation. Journal of Sex Medicine, 5, 1590-1606.

[9]   Rabijewski, M., Papierska, L., Kozakowski, J. and Zgliczyński, W. (2012) The High Prevalence of Testosterone Deficiency in Population of Polish Men over 65 Years with Erectile Dysfunctions. Aging Male, 15, 258-262.

[10]   Gandaglia, G., Briganti, A., Jackson, G., Kloner, R.A., Montorsi, F., Montorsi, P. and Vlachopoulos, C. (2013) A Systematic Review of the Association Between Erectile Dysfunction and Cardiovascular Disease. European Urology, [Epub ahead of print].

[11]   Orabi, H., Albersen, M. and Lue, T.F. (2011) Association of Lower Urinary Tract Symptoms and Erectile Dysfunction: Pathophysiological Aspects and Implications for Clinical Management. International Journal of Impotence Research, 23, 99-108.

[12]   Chung, S.D., Keller, J.J. and Lin, H.C. (2012) A Case-Control Study on the Association between Chronic Prostatitis/ Chronic Pelvic Pain Syndrome and Erectile Dysfunction. BJU International, 110, 726-730.

[13]   Chen, C.Y., Lee, C.P., Chen, Y., Jiang, J.R., Chu, C.L. and Chen, C.L.(2013) The Correlation between Emotional Distress and Aging Males’ Symptoms at a Psychiatric Outpatient Clinic: Sexual Dysfunction as a Distinguishing Characteristic between Andropause and Anxiety/Depression in Aging Men. Clinical Interventions in Aging, 8, 635-640.

[14]   Corona, G., Rastrelli, G., Monami, M., Maseroli, E., Jannini, E.A., Balercia, G., Sforza, A., Forti, G., Mannucci, E. and Maggi, M. (2013) Frequency of Sexual Activity and Cardiovascular Risk in Subjects with Erectile Dysfunction: Cross-Sectional and Longitudinal Analyses. Andrology, 1, 864-871.