CRCM  Vol.3 No.4 , April 2014
Primary Leiomyosarcoma of the Ovary: A Case Report
Abstract: Leiomyosarcoma of the ovary is a rare disease, with aggressive behavior and poor prognosis, which mainly occurs in postmenopausal women. Surgery is the cornerstone of treatment, while the role of chemotherapy and radiotherapy is still not clear because substantial data is lacking. This paper presents the case of an adult woman who is diagnosed with primary leiomyosarcoma of the left ovary, and who receives a surgical approach and adjuvant treatment with chemotherapy currently achieving 20 months free from disease.
Cite this paper: Rivas, G. , Bonilla, C. , Rubiano, J. and Arango, N. (2014) Primary Leiomyosarcoma of the Ovary: A Case Report. Case Reports in Clinical Medicine, 3, 192-196. doi: 10.4236/crcm.2014.34045.

[1]   Dixit, S., Singhal, S., Baboo, H.A., Vyas, R.K., Neema, J.P., Murthy, R. and Sooryanaraya, U. (1993) Leiomyosarcoma of the Ovary. Journal of Postgraduate Medicine, 39,151-153.

[2]   Bouie, S.M., Cracchiolo, B. and Heller, D. (2005) Epithelioid Leiomyosarcoma of the Ovary. Gynecologic Oncology, 97, 697-699.

[3]   Taskin, S., Taskin, E.A., Uzüm, N., Ataoglu, O. and Ortaç, F. (2007) Primary Ovarian Leiomyosarcoma: A Review of the Clinical and Immunohistochemical Features of the Rare Tumor. Obstetrical & Gynecological Survey, 62, 480-486.

[4]   Monk, B.J., Nieberg, R. and Berek, J.S. (1993) Primary Leiomyosarcoma of the Ovary in a Perimenarchal Female. Gynecologic Oncology, 48, 389-393.

[5]   Arslan, O.S., Sumer, C., Cihangiroglu, G., Kanat-Pektas, M. and Gungor, T. (2011) A Rare Tumor of the Female Genital Tract: Primary Ovarian Leiomyosarcoma. Archives of Gynecology and Obstetrics, 283, 83-85.

[6]   Azoury, R.S. and Woodruff, J.D. (1971) Primary Ovarian Sarcomas. Report of 43 Cases from the Emil Novak Ovarian Tumor Registry. Obstetrics & Gynecology, 37, 920-941.

[7]   Inoue, J., Gomibuchi, H. and Minoura, S. (2000) A Case of a Primary Ovarian Leiomyosarcoma. Journal of Obstetrics and Gynaecology Research, 26, 401-407.

[8]   Rasmussen, C.C., Skilling, J.S., Sorosky, J.I., Lager, D.J. and Buller, R.E. (1997) Stage IIIC Ovarian Leiomyosarcoma in a Premenopausal Woman with Multiple Recurrences: Prolonged Survival with Surgical Therapy. Gynecologic Oncology, 66, 519-525.

[9]   Dai, Y., Shen, K., Lang, J.H., et al. (2011) Primary Sarcoma or the Ovary: Clinicopathological Characteristics, Prognostic Factors and Evaluation of Therapy. Chinese Medical Journal, 124, 1316-1321.

[10]   Penel, N., Van Glabbeke, M., Marreaud, S., Ouali, M., Blay, J.Y. and Hohenberger, P. (2011) Testing New Regimens in Patients with Advanced Soft Tissue Sarcoma: Analysis of Publications from the Last 10 Years. Annals of Oncology, 22, 1266-1272.

[11]   Nasu, M., Inoue, J., Matsui, M., Minoura, S. and Matsubara, O. (2000) Ovarian Leiomyosarcoma: An Autopsy Case Report. Pathology International, 50,162-165.