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 JCT  Vol.5 No.4 , April 2014
Metastatic Rectal Adenocarcinoma of the Hip and Knee Joints: A Case Series
Adam C. Rothenberg, Karl J. Henrikson, Suzanne C. Schiffman, Mark A. Goodman
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Abstract: Two cases are presented of patients with a history of metastatic rectal adenocarcinoma presenting with a painful joint effusion. Both cases are potential examples of metastasis to periarticular bone with local infiltration to the synovium, which is one proposed mechanism of intrasynovial metastasis. While skeletal metastases are a relatively common occurrence in metastatic adenocarcinoma, intraarticular metastasis is extremely rare. These cases highlight the need to consider metastasis in the differential of joint swelling in the setting of a history of adenocarcinoma.
Keywords: Adenocarcinoma, Knee Joint, Hip Joint, Arthritis, Metastases, Synovial
Cite this paper: Rothenberg, A. , Henrikson, K. , Schiffman, S. and Goodman, M. (2014) Metastatic Rectal Adenocarcinoma of the Hip and Knee Joints: A Case Series. Journal of Cancer Therapy, 5, 323-330. doi: 10.4236/jct.2014.54039.
References

[1]   Currall, V.A. and Dixon, J.H. (2008) Synovial Metastasis: An Unusual Cause of Pain after Total Knee Arthroplasty. Journal of Arthroplasty, 23, 631-636. http://dx.doi.org/10.1016/j.arth.2007.04.034

[2]   Capovilla, M., et al. (2000) Chronic Monoarthritis and Previous History of Cancer: Think about Synovial Metastasis. Clinical Rheumatology, 26, 760-763.

[3]   Beckers, C., Foidart, J., Thiry, A. and Malaise, M.G. (2002) Synovial Metastasis from Colonic Cancer Presenting as Arthritis of the Knee: Characterization by 18FDG PET Scan. Revue Medicale de Liege, 57, 467-474.

[4]   Hatem, S.F., Petersilge, C.A. and Park, J.K. (1997) Musculoskeletal Case of the Day. Metastatic Carcinomatous Arthritis from Mucinous Adenocarcinoma of the Colon. Americal Journal of Roentgenology, 169, 291-292.

[5]   Goldenberg, D.L., Kelley, W. and Gibbons, R.B. (1975) Metastatic Adenocarcinoma of Synovium Presenting as an Acute Arthritis, Diagnosed by Closed Synovial Biopsy. Arthritis and Rheumatism, 18, 107-110. http://dx.doi.org/10.1002/art.1780180202

[6]   Graham, D.F. (1976) Hip Pain as a Presenting Symptom of Acetabular Metastasis. The British Journal of Surgery, 63, 147-148. http://dx.doi.org/10.1002/bjs.1800630217

[7]   Newton, P., Freemont, A.T., Noble, J., Scott, N., Grennan, D.M. and Hilton, R.C. (1984) Secondary Malignant Synovitis: Report of Three Cases and Review of the Literature. The Quarterly Journal of Medicine, 53, 135-143.

[8]   Evans, P.D. and Mintowt-Czyz, W.J. (1987) Late Metastasis of Carcinoma of the Colon to the Knee. Journal of the Royal College of Surgeons of Edinburgh, 32, 123-124.

[9]   MacAfee, K.A., Quinn, P.D. and Abaza, N.A. (1993) Adenocarcinoma of the Colon Metastatic to the Temporomandibular Joint: A Case Report. Journal of Oral and Maxillofacial Surgery, 51, 793-797. http://dx.doi.org/10.1016/S0278-2391(10)80426-4

[10]   Devis, P., Iwanik, D. and Aikens, C. (2005) Metastatic Adenocarcinoma Presenting as Monoarticular Arthritis of the Knee. American Journal of Roentgenology, 184, S107-S109.
http://dx.doi.org/10.2214/ajr.184.3_supplement.0184s107

 
 
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