ACT  Vol.3 No.1 , March 2014
Optimization of Contrast Material Dose for Abdominal Multi-Detector Row CT: Predicting Patient Lean Body Weight by Using Preliminary Transverse CT Images
Abstract: Estimated LBW could be used to determine the contrast material dose and rate during MDCT. The aim of this study is to test the accuracy of a technique for estimation of lean body weight (LBW) from a single multi-detector row computed tomographic (MDCT) abdominal image, using a bioelectrical body composition analyzer scale as the reference standard. CT images of 21 patients with previously measured LBW (mLBW) were processed using computer-assisted, vendor-specific software (Advantage Windows 4.2; GE Healthcare, Inc). For each transverse image, a fat-fraction was automatically measured as the number of fat pixels (-200 to -50 HU) divided by the total number of pixels having an attenuation value ≥-200 HU. Estimated LBW (eLBW) of five single contiguous sections was calculated in each of three abdominal regions (upper abdomen, mid abdomen and pelvis) by multiplying TBW by (1 – fat-fraction). Bland-Altman plot with limits of agreement was used to assess agreement between mLBW and eLBW. The mean mLBW for all patients was 56 kg (range, 39 - 75 kg). Mean differences and limits of agreement between mLBW and eLBW measurements for the upper abdomen, mid abdomen and pelvis reported were -8.9 kg (-25.6 kg, +7.5 kg), -10.6 kg (-27.7 kg, +6.4 kg), and +0.5 kg (-12.8 kg, +13.8 kg) respectively. eLBW deriving directly from a transverse CT image of the pelvis can accurately predict mLBW.
Cite this paper: Guerrisi, A. , Marin, D. , Barnhart, H. , Ho, L. , Toth, T. , Catalano, C. and Nelson, R. (2014) Optimization of Contrast Material Dose for Abdominal Multi-Detector Row CT: Predicting Patient Lean Body Weight by Using Preliminary Transverse CT Images. Advances in Computed Tomography, 3, 1-10. doi: 10.4236/act.2014.31001.

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