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 OJPed  Vol.4 No.1 , March 2014
Use of Complementary and Alternative Medicine in Siblings of Pediatric Cancer Patients in Germany. A Population-Based Survey
Abstract: Use of complementary and alternative medicine (CAM) in children with cancer is common and probably increasing. However data concerning use of CAM in siblings of children with an oncologic disease are missing so far. We conducted a population-based survey over a one-year period with 233 participants. Of the 209 respondents (90% response rate) 20% reported CAM use from the time on when the sibling was diagnosed to have cancer, compared to a prevalence rate of 48% before cancer diagnosis. The most prevalent therapies were homeopathy, anthroposophic medicine and Bach flowers. The main reasons for use were to strengthen the immune system and to achieve physical stabilization. Socio-demographic factors associated with CAM use were higher parental education and higher family income. A majority of CAM users would recommend them. 66% of the users informed a physician about CAM use. No side effects were reported.Conclusions: There is a significant decrease in CAM use in siblings of pediatric cancer patients after ascertainment of cancer in the affected sibling. Being out of the focus seems to be the main reason for non-use. Nevertheless the 20% CAM users rate CAM as very effective and would recommend CAM use to other parents.
Cite this paper: Gottschling, S. , Meyer, S. , Längler, A. , Ebinger, F. , Bialas, P. and Gronwald, B. (2014) Use of Complementary and Alternative Medicine in Siblings of Pediatric Cancer Patients in Germany. A Population-Based Survey. Open Journal of Pediatrics, 4, 93-101. doi: 10.4236/ojped.2014.41013.
References

[1]   Bishop, F.L., Prescott, P., Chan, Y.K., Saville, J., von Elm, E. and Lewith, G.T. (2010) Prevalence of Complementary Medicine Use in Pediatric Cancer: A Systematic Review. Pediatrics, 125, 768-776. http://dx.doi.org/10.1542/peds.2009-1775

[2]   Bold, J. and Leis, A. (2001) Unconventional Therapy Use among Children with Cancer in Saskatchewan. Journal of Pediatric Oncology Nursing, 18, 16-25. http://dx.doi.org/10.1053/jpon. 2001.20403

[3]   Clerici, C.A., Veneroni, L., Giacon, B., Mariani, L. and Fossati-Bellani, F. (2009) Complementary and Alternative Medical Therapies Used by Children with Cancer Treated at an Italian Pediatric Oncology Unit. Pediatric Blood & Cancer, 53, 599-604. http://dx.doi.org/10.1002/pbc.22093

[4]   Cohen, M.H., Kemper, K.J., Stevens, L., Hashimoto, D. and Gilmour, J. (2005) Pediatric Use of Complementary Therapies: Ethical and Policy Choices. Pediatrics, 116, e568-75. http://dx.doi.org/10. 1542/peds.2005-0496

[5]   Davis, M.P. and Darden, P.M. (2003) Use of Complementary and Alternative Medicine by Children in the United States. Archives of Pediatrics & Adolescent Medicine, 157, 393-396.
http://dx.doi.org/10.1001/archpedi.157.4.393

[6]   Eisenberg, D.M., Kessler, R.C., Foster, C., Norlock, F.E., Calkins, D.R. and Delbanco, T.L. (1993) Unconventional Medicine in the United States. Prevalence, Costs, and Patterns of Use. New England Journal of Medicine, 328, 246-252. http://dx.doi.org/10.1056/NEJM199301283280406

[7]   Ernst, E. (1999) Prevalence of Complementary/Alternative Medicine for Children: A Systematic Review. European Journal of Pediatrics, 158, 7-11. http://dx.doi.org/10.1007/s004310051000

[8]   Ernst, E. and Cassileth, B.R. (1998) The Prevalence of Complementary/Alternative Medicine in Cancer: A Systematic Review. Cancer, 83, 777-782. http://dx.doi.org/10.1002/(SICI)1097-0142 (19980815)83:4<777::AID-CNCR22>3.0.CO;2-O

[9]   Faw, C., Ballentine, R., Ballentine, L. and vanEys, J. (1977) Unproved Cancer Remedies. A Survey of Use in Pediatric Outpatients. JAMA, 238, 1536-1538. http://dx.doi.org/10.1001/jama.1977.032 80150106041

[10]   Fernandez, C.V., Stutzer, C.A., MacWilliam, L. and Fryer, C. (1998) Alternative and Complementary Therapy Use in Pediatric Oncology Patients in British Columbia: Prevalence and Reasons for Use and Nonuse. Journal of Clinical Oncology, 16, 1279-1286.

[11]   Genc, R.E., Senol, S., Turgay, A.S. and Kantar, M. (2009) Complementary and Alternative Medicine Used by Pediatric Patients with Cancer in Western Turkey. Oncology Nursing Forum, 36, E159-164. http://dx.doi.org/10.1188/09.ONF.E159-E164

[12]   Gomez-Martinez, R., Tlacuilo-Parra, A. and Garibaldi-Covarrubias, R. (2007) Use of Complementary and Alternative Medicine in Children with Cancer in Occidental, Mexico. Pediatric Blood & Cancer, 49, 820-823. http://dx.doi.org/10.1002/pbc.21101

[13]   Gottschling, S., Langler, A., Tautz, C. and Graf, N. (2006) Complementary and Alternative Medicine in Pediatric Oncology. Klinische P?diatrie, 218, 157-164. http://dx.doi.org/10.1055/s-2006-933400

[14]   Gottschling, S., Meyer, S., Langler, A., Scharifi, G., Ebinger, F. and Gronwald, B. (2014) Differences in Use of Complementary and Alternative Medicine between Children and Adolescents with Cancer in Germany. A Population Based Survey. Pediatric Blood & Cancer, 61, 488-492.
http://dx.doi.org/10.1002/pbc.24769

[15]   Gozüm, S., Arikan, D. and Büyükavci, M. (2007) Complementary and Alternative Medicine Use in Pediatric Oncology Patients in Eastern Turkey. Cancer Nursing, 30, 38-44.
http://dx.doi.org/10.1097/00002820-200701000-00007

[16]   Hamidah, A., Rustam, Z.A., Tamil, A.M., Zarina, L.A., Zulkifli, Z.S. and Jamal, R. (2009) Prevalence and Parental Perceptions of Complementary and Alternative Medicine Use by Children with Cancer in a Multi-Ethnic Southeast Asian Population. Pediatric Blood & Cancer, 52, 70-74.
http://dx.doi.org/10.1002/pbc.21798

[17]   Karali, Y., Demirkaya, M. and Sevinir, B. (2012) Use of Complementary and Alternative Medicine in Children with Cancer: Effect on Survival. Pediatric Hematology-Oncology, 29, 335-344.
http://dx.doi.org/10.3109/08880018.2012.670368

[18]   Kelly, K.M. (2007) Complementary and Alternative Medicines for Use in Supportive Care in Pediatric Cancer. Support Care Cancer, 15, 457-460. http://dx.doi.org/10.1007/s00520-006-0162-2

[19]   Kelly, K.M., Jacobson, J.S., Kennedy, D.D., Braudt, S.M., Mallick, M. And Weiner, M.A. (2000) Use of Unconventional Therapies by Children with Cancer at an Urban Medical Center. Journal of Pediatric Hematology/Oncology, 22, 412-416. http://dx.doi.org/10.1097/00043426-200009000-00005

[20]   L?ngler, A., Spix, C., Gottschling, S., Graf, N. and Kaatsch, P. (2005) Elternbefragung zur Anwendung Alternativer und Komplement?rer Behandlungsmethoden in der Kinderonkologie in Deutschland. Klinische P?diatrie, 217, 357-364. http://dx.doi.org/10.1055/s-2005-872522

[21]   Laengler, A., Spix, C., Seifert, G., Gottschling, S., Graf, N. and Kaatsch, P. (2008) Complementary and Alternative Treatment Methods in Children with Cancer: A Population-Based Retrospective Survey on the Prevalence of Use in Germany. European Journal of Cancer, 44, 2233-2240.
http://dx.doi.org/10.1016/j.ejca.2008.07.020

[22]   Lim, J., Wong, M., Chan, M.Y., Tan, A.M., Rajalingam, V., Lim, L.P., Lou, J. and Tan, C.L. (2006) Use of Complementary and Alternative Medicine in Paediatric Oncology Patients in Singapore. Annals Academy of Medicine Singapore, 35, 753-758.

[23]   Madsen, H., Andersen, S., Nielsen, R.G., Dolmer, B.S., H?st, A. and Damkier, A. (2003) Use of complementary/alternative medicine among paediatric patients. European Journal of Pediatrics, 162, 334-341.

[24]   Martel, D., Bussières, J.F., Théorêt, Y., Lebel, D., Kish, S., Moghrabi, A. and Laurier, C. (2005) Use of Alternative and Complementary Therapies in Children with Cancer. Pediatric Blood & Cancer, 44, 660-668. http://dx.doi.org/10.1002/pbc.20205

[25]   McCurdy, E.A., Spangler, J.G., Wofford, M.M., Chauvenet, A.R. and McLean, T.W. (2003) Religiosity Is Associated with the Use of Complementary Medical Therapies by Pediatric Oncology Patients. Journal of Pediatric Hematology/Oncology, 25, 125-129. http://dx.doi.org/10.1097/00043426-200302000-00008

[26]   Mertens, A.C., Sencer, S., Myers, C.D., Recklitis, C., Kadan-Lottick, N., Whitton, J., Marina, N., Robison, L.L. and Zeltzer, L. (2008) Complementary and Alternative Therapy Use in Adult Survivors of Childhood Cancer: A Report from the Childhood Cancer Survivor Study. Pediatric Blood & Cancer, 50, 90-97. http://dx.doi.org/10.1002/pbc.21177

[27]   Molassiotis, A. and Cubbin, D. (2004) Thinking outside the Box: Complementary and Alternative Therapies Use in Paediatric Oncology Patients. European Journal of Oncology Nursing, 8, 50-60. http://dx.doi.org/10.1016/S1462-3889(03)00054-1

[28]   Mottonen, M. and Uhari, M. (1997) Use of Micronutrients and Alternative Drugs by Children with Acute Lymphoblastic Leukemia. Medical and Pediatric Oncology, 28, 205-208.
http://dx.doi.org/10.1002/(SICI)1096-911X(199703)28:3<205::AID-MPO10>3.0.CO;2-D

[29]   Ndao, D.H., Ladas, E.J., Bao, Y., Cheng, B., Nees, S.N., Levine, J.M. and Kelly, K.M. (2013) Use of Complementary and Alternative Medicine among Children, Adolescent, and Young Adult Cancer Survivors: A Survey Study. Journal of Pediatric Hematology/Oncology, 35, 281-288.
http://dx.doi.org/10.1097/MPH.0b013e318290c5d6

[30]   Paisley, M.A., Kang, T.I., Insogna, I.G. and Rheingold, S.R. (2011) Complementary and Alternative Therapy Use in Pediatric Oncology Patients with Failure of Frontline Chemotherapy. Pediatric Blood & Cancer, 56, 1088-1091. http://dx.doi.org/10.1002/pbc.22939

[31]   Pendergrass, T.W. and Davis, S. (1981) Knowledge and Use of “Alternative” Cancer Therapies in Children. The American journal of pediatric hematology/oncology, 3, 339-345.

[32]   Post-White, J., Fitzgerald, M., Hageness, S. and Sencer, S.F. (2009) Complementary and Alternative Medicine Use in Children with Cancer and General and Specialty Pediatrics. Journal of Pediatric Oncology Nursing, 26, 7-15. http://dx.doi.org/10.1177/1043454208323914

[33]   Sawyer, M.G., Gannoni, A.F., Toogood, I.R., Antoniou, G. and Rice, M. (1994) The Use of Alternative Therapies by Children with Cancer. Medical Journal of Australia, 160, 320-322.

[34]   Singendonk, M., Kaspers, G.J., Naafs-Wilstra, M., Meeteren, A.S., Loeffen, J. and Vlieger, A. (2013) High Prevalence of Complementary and Alternative Medicine Use in the Dutch Pediatric Oncology Population: A Multicenter Survey. European Journal of Pediatrics, 172, 31-37.
http://dx.doi.org/10.1007/s00431-012-1821-6

[35]   Spigelblatt, L., La?né-Ammara, G., Pless, I.B. and Guyver, A. (1994) The Use of Alternative Medicine by Children. Pediatrics, 94, 811-814.

[36]   Tomlinson, D., Hesser, T., Ethier, M.C. and Sung, L. (2011) Complementary and Alternative Medicine Use in Pediatric Cancer Reported during Palliative Phase of Disease. Support Care Cancer, 19, 1857-1863. http://dx.doi.org/10.1007/s00520-010-1029-0

[37]   Weyl Ben Arush, M., Geva, H., Ofir, R., Mashiach, T., Uziel, R. and Dashkovsky, Z. (2006) Prevalence and Characteristics of Complementary Medicine Used by Pediatric Cancer Patients in a Mixed Western and Middle-Eastern Population. Journal of Pediatric Hematology/Oncology, 28, 141-146. http://dx.doi.org/10.1097/01.mph.0000210404.74427.10

[38]   Yeh, C.H., Tsai, J.L., Li, W., Chen, H.M., Lee, S.C., Lin, C.F. and Yang, C.P. (2000) Use of Alternative Therapy among Pediatric Oncology Patients in Taiwan. Pediatric Hematology-Oncology, 17, 55-65. http://dx.doi.org/10.1080/088800100276668

[39]   Gottschling, S., Gronwald, B., Schmitt, S., Schmitt, C., L?ngler, A., Leidig, E., Meyer, S., Baan, A., Shamdeen, M.G., Berrang, J. and Graf, N. (2013) Use of Complementary and Alternative Medicine in Healthy Children and Children with Chronic Medical Conditions in Germany. Complementary Therapies in Medicine, 21, S61-69. http://dx.doi.org/10.1016/j.ctim.2011.06.001

[40]   http://nccam.nih.gov/health/whatiscam

[41]   Altunc, U., Pittler, M.H. and Ernst, E. (2007) Homeopathy for Childhood and Adolescence Ailments: Systematic Review of Randomized Clinical Trials. Mayo Clinic Proceedings, 82, 69-75.

[42]   Langler, A., Boeker, R., Kameda, G., Seifert, G., Edelhauser, F. and Ostermann, T. (2013) Attitudes and Beliefs of Paediatric Oncologists Regarding Complementary and Alternative Therapies. Complementary Therapies in Medicine, 21, S10-19 http://dx.doi.org/10.1016/j.ctim.2012.02.006

 
 
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