Health  Vol.6 No.8 , March 2014
Illegal Use of Clenbuterol in Cattle Production in México
Abstract: Slaughtered cattle (n = 582) from México State were bled for a serological screening of clenbuterol residues, using a commercial enzyme-linked immunosorbent assay (ELISA). Clenbuterol residues were found in a total of 153/582 (26.2%) sera analysed. These results reinforced the assumption of the illegal use of clenbuterol in cattle production in México; therefore, routine screening examinations in slaughtered cattle were strongly advised considering the toxic potential for humans.
Cite this paper: Valladares-Carranza, B. , Bañuelos-Valenzuela, R. , Peña-Betancourt, S. , Velázquez-Ordoñez, V. , Velázquez-Armenta, Y. and Nava-Ocampo, A. (2014) Illegal Use of Clenbuterol in Cattle Production in México. Health, 6, 673-676. doi: 10.4236/health.2014.68087.

[1]   Cristino, A., Ramos, F. and da Silveira, M.I.N. (2003) Control of the Illegal Use of Clenbuterol in Bovine Production. Journal of Pharmaceutical and Biomedical Analysis, 32, 311-316.

[2]   Jelka, P., Vulic, A., Mitac, M., Persi, N. and Milic, D. (2011) Determination of Clenbuterol Residues in Retinal Tissue of Food-Producing Pigs. Journal of Analytical Toxicology, 35, 28-31.

[3]   Salquebre, G., Bresson, M., Villain, M.,Cirimile, V. and Kintz, P. (2007) Clenbuterol Determination in Calf Hair by UPLC-MS-MS: Case Report of a Fraudulent Use for Cattle Growth. Journal of Analytical Toxicology, 31, 114-118.

[4]   Valladares-Carranza, B., Velázquez-Ordoñez, V., Zamora-Espinosa, J.L., Aviles-Martínez, J.A., Zaragoza-Bastida, A. and Posadas-Sánchez, M.A. (2013) Implications of the Use of Clenbuterol Hydrochloride in Beef Cattle. In: Salem, A.F.Z.M., Ed., Nutritional Strategies of Animal Feed Additives, Nova Science Publishers, Inc., New York, 185-196.

[5]   NOM-EM-015-ZOO-2002 (2002) Especificaciones Técnicas Para el Control del Uso de Beta-Agonistas en Los Animales. Secretaría de Agricultura, Ganadería, Desarrollo Rural, Pesca y Alimentación. Diario Oficial de la Federación. 1 de Marzo de 2002. México.

[6]   Ortiz, B.J.C., Alcocer, V.V.M. and Castellanos, R.A.F. (2005) Determinación de Clenbuterol por el Método de Gases/Masas y su Cuantificación en Bovinos Sacrificados en dos Rastros. Técnica Pecuaria en México, 42, 57-67.

[7]   R-Biopharm. RIDASCREEN? (2014) Clenbuterol Fast. Manual del Kid. R-Biopharm AG. Darmstadt. Art. No. R1701C.

[8]   Brambilla, G., Cenci, T., Franconi, F., Galarini, R., Macrì, A., Rondoni, F., Strozzi, M. and Loizzo, A. (2000) Clinical and Pharmacological Profile in a Clenbuterol Epidemic Poisoning of Contaminated Beef Meat in Italy. Toxicology Letters, 114, 47-53.

[9]   Pulce, C., Lamaison, D., Keck, G. and Bastuiromois, C. (1991) Collective Human Food Poisoning by clenbuterol Residues in Veal Liver. Veterinary and Human Toxicology, 33, 480-485.

[10]   García, L.L. (2002) Alerta Epidemiológica por la Intoxicación en Humanos con Clenbuterol y su Empleo en la Alimentación de Ganado. Revista de Sanidad Militar, 56, 131-134.

[11]   Prezelj, A., Obreza, A. And Pecar. S. (2003) Abuse of Clenbuterol and Its Detection. Current Medical Chemistry, 10, 281-290.