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 OJOG  Vol.4 No.5 , March 2014
Neonatal Alloimmune Thrombocytopenia Due to Maternal Anti HPA1a Antibodies: Case Report and Management of Subsequent Pregnancy
Abstract: Fetoneonatal alloimmune thrombocytopenia is an infrequent and severe disease that is unexpectedly found after an uncomplicated first pregnancy. Affected infants might show unexplained purpura, intracranial hemorrhage, and/or gastrointestinal or genitourinary hemorrhage. Nevertheless, in asymptomatic newborns the thrombocytopenia may be discovered incidentally. We describe a case report that highlights that the incidental diagnosis of FNAIT allows both properly managing the newborn, and detecting maternal anti-HPA1a antibodies in order to prevent the disease in subsequent pregnancies. A non-invasive treatment based on IVIgG allowed to this patient to prevent FNAIT in her second pregnancy.
Cite this paper: Cruz, V. , Martínez-Varea, A. , Núñez-Valera, M. , Abad-Carrascosa, A. , Diago, V. and Perales-Marín, A. (2014) Neonatal Alloimmune Thrombocytopenia Due to Maternal Anti HPA1a Antibodies: Case Report and Management of Subsequent Pregnancy. Open Journal of Obstetrics and Gynecology, 4, 213-216. doi: 10.4236/ojog.2014.45035.
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http://dx.doi.org/10.1182/blood-2013-02-481887

 
 
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