Health  Vol.3 No.3 , March 2011
Mycobacterium tuberculosis in the aorta of a patient with takayasu’s arteritis. extra pulmonary tuberculosis
ABSTRACT
Takayasu’s arteritis (TA), of unknown etiology, has been related with Mycobacterium tuberculosis infection. The published cases are controversial. A 29- year-old man died, prolapse of the aortic valve and unspecific arteritis were demonstrated at necropsy. Our objective was to search in the fresh aortic tissues, the infectious agent of tuberculosis through culture, as well as by performing histopathology and searching by the molecular study, sequences of genes associated to micobacteria and Ziehl’s stain. Results. The bacillus of tuberculosis was observed by the Ziehl’s stain and the sequences of insertion IS6110 gene were identified. Our findings support the relation of TA with possible tuberculosis infection.Conclusion. The possibility that Takayasu’s arteritis is an extra pulmonary tu-berculosis must be explored.

Cite this paper
nullSoto, M. , Soto, V. , Sandría, J. , Gamboa, R. and Huesca, C. (2011) Mycobacterium tuberculosis in the aorta of a patient with takayasu’s arteritis. extra pulmonary tuberculosis. Health, 3, 159-161. doi: 10.4236/health.2011.33030.
References
[1]   Savory, W. S. (1856) Case of a Young Woman in whom the main Arteries of both Upper Extremities and of the Left Side of the Neck were throughout completely Oblite- rated. Medico-Chirurgical Transactions, 39, 205-219.

[2]   Numano, F. (2000) Vasa vasoritis, vasculitis and athero- sclerosis. International Journal of Cardiology, 75, S1 - S8.

[3]   Hotchi, M. (1992) Pathological studies on Takayasu arteritis. Heart and Vessels, 7, 11-17.

[4]   Pantell, R.H. and Goodman, B.W., Jr. (1981) Takayasu’s arteritis: The relationship with tuberculosis. Pediatrics, 67, 84-88.

[5]   Lupi, H. E., Sanchez, T. G. and Castillo, P. U. (1972). Cutaneous reactivity to P.P.D. and antigens of atypical mycobacteria (kansash avium and fortuitum) in patients with unespecific arteritis. Archivos del Instituto de Cardiología de Mexico, 42, 717-725.

[6]   Lupi-Herrera, E., Sanchez-Torres, G., Marcushamer, J., Mispireta, J., Horwitz and S. and Vela, J.E. (1977) Taka- yasu’s arteritis. Clinical study of 107 cases. American. Heart Journal, 93, 94-103. doi:10.1016/S0002-8703(77)80178-6

[7]   Robles, M. and Reyes, P.A. (1994) Takayasu’s arteritis in Mexico: A clinical review of 44 consecutive cases. Clinical and Experimental Rheumatology, 12, 381-388.

[8]   Soto, M. E., Espinola, N., Flores-Suarez, L.F.and Reyes, P.A. (2008) Takayasu arteritis: Clinical features in 110 Mexican Mestizo patients and cardiovascular impact on survival and prognosis. Clinical and experimental rheumatology, 26, S9-S15.

[9]   Arnaud, L., Cambau, E. and Brocheriou, I. et al. (2009) Absence of Mycobacterium tuberculosis in arterial lesions from patients with Takayasu’s arteritis. The Journal of Rheumatology, 36, 1682-1685.

[10]   Sagar, S., Ganguly, N.K., Koicha, M.and Sharma, B.K. (1992) Immunopathogenesis of Takayasu arteritis. Heart and Vessels, 7, 85-90. doi:10.1007/BF01744550

[11]   Serratrice, J., Benyamine, A. and Vidal, V., et al. (2008) Simultaneous occurrence of diffuse Takayasu’s arteritis and severe disseminated tuberculosis. La Revue de Médecine Interne, 29, 520-523.

[12]   Van Vleet, M. E. and Edwards, J. E. (1954) Histologic study of intrapulmonary vessels in tuberculosis. A. M. A. Archives of Pathology, 58, 168-175.

 
 
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