Surface epithelial-stromal tumors are the most common
neoplasm of ovary in the reproductive age and beyond. Less than 1% of
epithelial ovarian tumors occur before the age of 21 years while 75% of sexcord
stromal tumors (Sertoli and Leydig Cell) occur in the third and fourth decades
of life. Serous tumors rarely occur in combination with germ cell tumors,
sex-cord stromal tumors or granulosa cell tumors. Thus it is extremely rare for
a combination of the above two tumors to occur before 21 years although a case
report for a tumor with epithelial, stromal and sex-cord stromal elements for a
58-year-old patient has been documented. We believe ours is the first case in
literature of a massive Serous Cystadenoma with co-existing stromal tumor with minor sex-cord stromal (Sertoli-Leydig
Cite this paper
Bachhav, A. (2014) Serous cystadenoma with co-existing stromal tumor with sex-cord stromal elements: An extremely rare tumor. Open Journal of Obstetrics and Gynecology
, 105-108. doi: 10.4236/ojog.2014.43019
 Russel, P. (1994) Surface epithelial stromal-tumors of the ovary. In: Kurman, R.J., Ed., Blaustein’s Pathology of the Female Genital Tract, 4th Edition, Spinger-Verlag, New York, 724.
 Young, R.H. and Scully, R.E. (1983) Ovarian stromal tumors with minor sex cord elements: A report of seven cases. The International Journal of Gynecological Pathology, 2, 227-234.
 Yang, S.W., Cho, M.Y., Jung, S.H., Lee, K.G., Cha, D.S. and Kim, K.R. (2001) Mucinous cystadenoma coexisting with stromal tumor with minor sex-cord elements of the ovary: A case report. Journal of Korean Medical Science, 16, 237-240.
 Young, R.H. (2011) Blaustein’s pathology of the female genital tract. In: Kurman, R.J., Hedrick Ellenson, L. and Ronnett, B.M., Eds., 6th Edition, Springer, New York, 786.
 Fox, H. and Wells, M. (2003) Surface epithelial stromal tumors of the ovary. In: Fox, H. and Wells, M., Eds., Haines & Taylor Obstetrical and Gynaecological Pathology, Vol. 1, Churchill Livingstone, Madrid.
 Kommoss, F., Oliva, E., Bhan, A.K., Young, R.H. and Scully, R.E. (1998) Inhibin expression in ovarian tumors and tumor-like lesions: An immunohistochemical study. Modern Pathology: An Official Journal of the United States and Canadian Academy of Pathology, 11, 656-664.
 Movahedi-Lankarani, S.M.D. and Kurman, R.J.M.D. (2002) Calretinin, a more sensitive but less specific marker than [alpha]-inhibin for ovarian sex cord-stromal neoplasms: An immunohistochemical study of 215 cases. American Journal of Surgical Pathology, 26, 1477-1483.
 Lee, K.R., Tavassoli, F.A., Prat, J., et al. Surface epithelial-stromal tumors. In: Tavassoli, F.A. and Devilee, P., Eds., Pathology & Genetics of Tumors of the Breast and Female Genital Organs, IARC Press, Lyon, 124.