Objective: To improve the clinical differential diagnosis level, the clinical manifestation of the brucellar spondylitis and the spine turberculosis were discussed in this paper. Method: The study was completed in the No. 1 Affiliated Hospital of Hebei North University in Zhangjiakou City, Hebei Province, China, from January 2001 to December 2013 by Analyzing the X-ray, CT scanning and MRI of 257 cases of the brucellar spondylitis retrospectively and comparing with the clinical imageology and pathology 332 cases of turberculosis of the spine diagnosed finally. Results: The brucellar spondylitis: The focuses usually locate in the lumbar vertebra and L4, 5 has the highest occurrence rate. The focuses are often small but multiple, and limited to the edge of the vertebra. Hyperostosis and osteoscterosis are usually found in the tissuses around the focuses. There are often new focuses in the newborn bones, and the destruction of intervertebral discs is usually slight. Hyperostosis and osteoscterosis might be found in the surfaces of the joints. The densites of the bones close to the focuses become high. There were less or no paravertebral abscesses but inflammational granuloma can be found frequently. Turberculosis of the spine: The focuses are usually located in the thoracic and lumbar vertebra, and are characterized by the destruction of the vertebra and the intervertebral discs, accompanied by the appearance of dead bones. In most cases, paravertebral abscesses and osteoporosis might be found. Conclusions: The specific manifestation of the clinical imageology can help to differentiate the brucelar spondylitis from the turberculosis of the spine.
 T. Turunc, Y. Z. Demiroglu, H. Uncu, S. Colakoglu and H. Arslan, “A Comparative Analysis of Tuberculous, Brucellar and Pyogenic Spontaneous Spondylodiscitis Patients,” Journal of Infection, Vol. 55, No. 2, 2007, pp. 158-163. http://dx.doi.org/10.1016/j.jinf.2007.04.002
 M. H. Yilmaz, B. Mete, F. Kantarci, R. Ozaras, H. Ozer, A. Mert, I. Mihmanli, R. Ozturk and K. Kanbergoglu, “Tuberculous, Brucellar and Pyogenic Spondylitis: Comparison of Magnetic Resonance Imaging Findings and Assessment of Its Value,” South Medical Journal, Vol. 100, No. 6, 2007, pp. 613-614. http://dx.doi.org/10.1097/SMJ.0b013e3180600eaa
 E. T. Tali, “Spinal Infections,” European Journal of Radiology, Vol. 50, No. 2, 2004, pp. 120-133. http://dx.doi.org/10.1016/j.ejrad.2003.10.022
 G. Bianco, M. E. Pompeo, C. Mastroianni, G. Trasimeni, A. Paris, S. Coletta, V. Vullo, P. Serra and M. Venditti, “Non-Tubercular and Non-Brucellar Spondylodiscitis: Preliminary Clinico-Microbiologic Analysis of 37 Cases,” Recenti Progressi in Medicina, Vol. 94, No. 12, 2003, pp. 554-559.
 J. S. G. del. Pozo, M. V. Soto, M. Lizan-Garcia, E. Martinez-Alfaro, J. C. Segura-Luque and J. Solera-Santos, “Incidence of Infectious Spondylitis in the Province of Albacete (Spain),” Enfermedades Infecciosasy Microbiología Clínica, Vol. 23, No. 9, 2005, pp. 545-550.
 Y. A. Gokhale, A. G. Ambardekar, A. Bhasin, M. Patil, A. Tillu and J. Kamath, “Brucella Spondylitis and Sacroiliitis in the General Population in Mumbai,” Journal of the Association of Physicians of India, Vol. 51N, 2003, pp. 659-666.
 G. S. Guven, B. Cakir, G. Oz, M. D. Tanriover, E. Turkmen and T. Sozen, “Could Remembering the Prozone Phenomenon Shorten Our Diagnostic Journey in Brucellosis?” Rheumatology International, Vol. 26, No. 10, 2006, pp. 933-935. http://dx.doi.org/10.1007/s00296-006-0118-3
 M. Turgut, A. T. Turgut and U. Kosar, “Spinal Brucellosis: Turkish Experience Based on 452 Cases Published during the Last Century,” Acta Neurochirgica, Vol. 148, No. 10, 2006, pp. 1033-1044. http://dx.doi.org/10.1007/s00701-006-0877-3
 G. Aydin, A. Tosun, I. Keles, E. Ayaslioglu, O. Tosun and S. Orkun, “Brucellar Spondylodiscitis: A Case Report,” International Journal of Clinical Practice, Vol. 60, No. 11, 2006, pp. 1502-1505.
 B. S. Tur, N. Suldur, S. Ataman, E. A. Ozturk, A. Bingol and M. B. Atay, “Brucellar Spondylitis: A Rare Cause of Spinal Cord Compression,” Spinal Cord, Vol. 42, No. 5, 2004, pp. 321-324.
 J. S. G. del Pozo, M. V. Soto and J. Solera, “Vertebral Osteomyelitis: Long-Term Disability Assessment and Prognostic Factors,” Journal of Infection, Vol. 54, No. 2, 2007, pp. 129-134.
 K. Z. Yuksel, M. Senoglu, M. Yuksel and M. Gul, “Brucellar Spondylo-Discitis with Rapidly Progressive Spinal Epidural Abscess Presenting with Sciatica,” Spinal Cord, Vol. 44, No. 12, 2006, pp. 805-808. http://dx.doi.org/10.1038/sj.sc.3101938
 P. Atonis, M. Tzermiadianos, A. Gikas, P. Papagelopoulos and A. Hadjipavlou, “Surgical Treatment of Spinal Brucellosis,” Clinical Orthopaedics & Related Research, Vol. 444, 2006, pp. 66-72.
 C. Marrakchi, B. Kilani, F. Kanoun, R. Abdelmalek, H. Tiouiri, A. Goubontini, F. Zouiten, K. Ezzaouia, M. Kooli, M. Khalfaoui and T. Ben-Chaabane, “Melitococcal Psoas Abscesses: Study of Three Cases and Review of the Literature,” Médecine Tropicale, Vol. 66, No. 3, 2006, pp. 261-265.
 D. Ozol, A. Koktener and M. E. Uyar, “Active Pulmonary Tuberculosis with Vertebra and Rib Involvement: Case Report,” South Medical Journal, Vol. 99, No. 2, 2006, pp. 171-173.
 M. Bosilkovski, L. Krteva, S. Caparoska and M. Dimzova, “Osteoarticular Involvement in Brucellosis: Study of 196 Cases in the Republic of Macedonia,” Croatian Medical Journal, Vol. 45, No. 6, 2004, pp. 727-733.
 M. A. Pina, P. J. Modrego and J. J. Uro, “Brucellar Spinal Epidural Abscess of Cervical Location: Report of Four Cases,” European Neurology, Vol. 45, No. 4, 2001, p. 249. http://dx.doi.org/10.1159/ 000052137
 M. Namiduru, I. Karaoglan and S. Gursoy, “Brucellosis of the Spine: Evaluation of the Clinical, Laboratory, and Radiological Findings of 14 Patients,” Rheumatology International, Vol. 24, No. 3, 2004, pp. 125-129. http://dx.doi.org/10.1007/s00296-003-0339-7
 D. Olivares, V. N. Lopez, R. Serrano and F. L. Garcia, “Brucellosis Complicated by a Psoas Muscle Abscess,” Enfermedades Infecciosasy Microbiología Clínica, Vol. 22, No. 3, 2004, p. 200.
 H. P. Ledermann, M. E. Schweitzer and W. B. Morrison, “MR Imaging Findings in Spinal Infections: Rules or Myths?” Radiology, Vol. 228, No. 2, 2003, p. 506. http://dx.doi.org/10.1148/radiol.228 2020752
 S. Moorthy and N. K. Prabhu, “Spectrum of MR Imaging Findings in Spinal Tuberculosis,” American Journal of Roentgenology, Vol. 179, No. 4, 2002, pp. 979-983. http://dx.doi.org/10.2214/ajr.179.4.17 90979
 I. Demirci, “Brucella Diskitis Mimicking Herniation without Spondylitis: MRI Findings,” Zentralbl Neurochir, Vol. 64, No. 4, 2003, pp. 178-181. http://dx.doi.org/10.1055/s-2003-44622
 A. Cascio, C. Iaria, A. Campenni, A. Blandino and S. Baldari, “Use of Sulesomab in the Diagnosis of Brucellar Spondylitis,” Clinical Microbiology and Infection, Vol. 10, No. 11, 2004, pp. 178-181.