NM  Vol.2 No.1 , March 2011
Reduced Risk of Cancer in Patients with Bipolar Affective Disorder
Background: research focusing on incidence of cancer amongst bipolar affective disorder (BAD) is sparse. Aim: to ex-amine the incidence of cancer in a cohort of BAD inpatients. Methods: the study sample was comprised of BAD patients who had been admitted to a tertiary care mental health center during the period: 1990 to 2006. The data for the sample was cross-referenced with the National Cancer Registry. Analyses of Standardized Incidence Rates (SIR) for all organ systems malignancies were performed. Results: of 1,638 BAD patients included in the present study, 72 (0.04%) were diagnosed as suffering from co-morbid malignancy. This reflects a significantly reduced risk; SIR of 0.27 (95% CI 0.21-0.34). Reduced risk of cancer held true for both males and females (0.20 and 0.34, respectively). Nineteen women developed breast cancer; SIR = 0.42 (95% CI 0.25-0.66). Conclusions: the present study demonstrates reduced rates of cancer amongst patients suffering from BAD - with special reduction in breast cancer.

Cite this paper
nullE. Rosenshfir, P. Shemesh, D. Aizenberg and Y. Barak, "Reduced Risk of Cancer in Patients with Bipolar Affective Disorder," Neuroscience and Medicine, Vol. 2 No. 1, 2011, pp. 57-60. doi: 10.4236/nm.2011.21008.
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