ABC  Vol.4 No.1 , February 2014
Phytoecdysteroids from Silene praemixta
Abstract: The waste products of the production of ecdysterone (3) from Silene praemixta M. Pop. (Caryophyllaceae) were investigated. The column chromatography of the technological waste has allowed to isolating 2-de- soxyecdysone (1), 2-deoxyecdysterone (2), ecdysterone (3) and 22-O-β-D-glucopyranoside of 2-deoxyecdy- sone (4). Glucoside 4 was found for the first time in the plant Silene praemixta. Ecdysteroids 1, 2 prevailed in the sum. Compounds 3 and 4 were minor components of the waste products. The identification of com- pounds 1-4 was carried out by using the modern me- thods of 1D and 2D NMR spectroscopy: 1H, 13C, DEPT, 1H-1H COSY, HSQC, NOESY, IR spectroscopy and ESI MS.
Cite this paper: Agzamova, M. , Ogly Isaev, I. , Mamathanov, A. , Ogly Isaev, M. and Ibragimov, T. (2014) Phytoecdysteroids from Silene praemixta. Advances in Biological Chemistry, 4, 1-4. doi: 10.4236/abc.2014.41001.

[1]   Saatov, Z., Gorovits, M.B. and Abubakirov, N.K. (1993) Phytoecdysteroids of plants of the genus Silene. Chemistry of Natural Compounds, 29, 551-557.

[2]   Báthori, M., Tóth, N., Hunyadi, A., Márki, á. and Zádor, E. (2008) Phytoecdysteroids and anabolic-androgenic steroids—Structure and effects on humans. Current Medicinal Chemistry, 15, 75-91.

[3]   Bobkov, Y.G., Vinogradov, V.M., Katkov, V.F., Losev, S.S. and Smirnov, A.V. (1984) Pharmacological improvement of fatigue. Medicine, Moscow, 208.

[4]   Galbraith, M.N., Horn, D.H.S., Middleton, E.J. and Hackney R.J. (1968) Structure of deoxycrustecdysone, a second crustacean moulting hormone. Chemical Communications, 2, 83-85.

[5]   Chong, Y.K., Galbraith, M.N. and Horn, D.H.S. (1970) Isolation of deoxyecrustecdysone, deoxyecdysone, and α-ecdysone from the fern Blechnum minus. Journal of the Chemical Society D: Chemical Communications, 18, 1217-1218.

[6]   Saatov, Z., Usmanov, B.Z. and Abubakirov, N.K. (1979) Phytoecdyzones of Silene praemixta. II. Premistesteron. Chemistry of Natural Compounds, 15, 703-705.

[7]   Baltaev, U.A. and Abubakirov, N.K. (1987) Phytoecdysteroids of Rhaponticum carthamoides. Chemistry of Natural Compounds, 23, 565-568.

[8]   Lafont, R., Harmatha, J., Marion-Poll, F., Dinan, L. and Wilson, I.D. (2002) Ecdybase—The ecdysone handbook, 3rd Edition.