CRCM  Vol.3 No.2 , February 2014
Accessory breast poorly differentiated adenocarcinoma with positive HER2 gene amplification: A case report
Abstract: Background: Primary poorly differentiated adenocarcinoma of the accessory breast is rare. We report such a case in a 56-year-old Malaysian woman of Indian ethnicity. Case Presentation: An axillary swelling measuring 5 × 5 cm on excisional biopsy revealed a poorly differentiated adenocarcinoma with positive HER2 gene amplification. Conclusion: Overall prognosis is similar to that of a carcinoma of the normal breast, therefore early diagnosis is imperative to ascertain curable status and improve prognosis.
Cite this paper: Balasingam, D. , Thangaratnam, R. and Kumar, J. (2014) Accessory breast poorly differentiated adenocarcinoma with positive HER2 gene amplification: A case report. Case Reports in Clinical Medicine, 3, 79-81. doi: 10.4236/crcm.2014.32019.

[1]   Gutermuth, J., Audring, H., Voit, C. and Haas, N. (2006) Primary carcinoma of ectopic axillary breast tissue. Journal of the European Academy of Dermatology and Venereology, 20, 217-221.

[2]   Dhebri, A., Shah, N., Sripadam, R. and Arora, P.K. (2012) Skin lesion in axilla: An unusual presentation of invasive lobular carcinoma of breast. BMJ Case Reports.

[3]   Youn, H.J. and Jung, S.H. (2009) Accessory breast carcinoma. Breast Care, 4, 104-106.

[4]   Goyal, S., Puri, T., Gupta, R., Julka, P.K. and Rath, G.K. (2008) Accessory breast tissue in axilla masquerading as breast cancer recurrence. Journal of Cancer Research and Therapeutics, 4, 95-96.

[5]   Devine, C., Carol-Ann, C., Deb, R. and Agrawal, A. (2013) Invasive lobular carcinoma arising in accessory breast tissue. World Journal of Surgical Oncology, 11, 47.

[6]   Azuma, T., Yamamoto, K., Kobayashi, T. and Nakano, H. (1997) Accessory breast cancer: A case report of carcinoma originating from aberrant breast tissue in the axillary region. Journal of Breast Cancer, 4, 49-52.

[7]   Giron, G., Friedman, I. and Feldman, S. (2004) Lobular carcinoma in ectopic axillary breast tissue. The American Surgery, 70, 312-315.

[8]   Evans, D.M. and Guyton, D.P. (1995) Carcinoma of the axillary breast. Journal of Surgical Oncology, 59, 190-195.

[9]   Brufsky, A.M., et al. (2013) EMILIA trial: T-DM1 in metastatic breast cancer.

[10]   National Cancer Institute (2012) Treatment options for HER2-positive breast cancer expand and evolve. NCI Cancer Bulletin, 9.