In this paper, the problems of rational use, protection and management of water and irrigated land resources of Uzbekistan are discussed. Uzbekistan is using more than 50% water resources of the region and therefore it’s more vulnerable to the problems of water deficiency and pollution caused by mismanagement, use of outdated technologies, and climate change impact. Utilization of water resources on main branches of economy (irrigation, industry and drinking water supply) from 2000-2009 and in some cases beyond this period was analyzed. Based on the data analyzed, the conditions of irrigated land degradation in Uzbekistan are estimated. The results of this analysis suggest several possibilities toward a sustainable use of irrigated lands: i) reduction of the groundwater table depth; ii) decrease of the level of mineralization of groundwater, and iii) improvement of ameliorative conditions of irrigated lands. The causes resulting in degradation of the irrigated lands and practical measures on the reduction of salinization of the irrigated lands are also recommended.
 B. B. Alihanov, “About a Condition of Environment and Use of Natural Resources in Republic of Uzbekistan (the Retrospective Analysis for 1988-2007), National Report of the State Committee for Nature Protection of the Republic of Uzbekistan,” Chinor ENK, Tashkent, 2008.
 “The Reports of the State Department of Statistics of Uzbekistan,” Tashkent, 2012. www.statistics.uz.
 R. Kulmatov, “Modern Problems in Using, Protecting and Managing Water and Land Resources of the Aral Sea Basin,” In: J. Qi and K. T. Evered, Eds., Environmental Problems of Central Asia and Their Economic, Social and Security Impacts, Springer, Dordrecht, 2008, pp. 24-32. http://dx.doi.org/10.1007/978-1-4020-8960-2_2
 Asian Development Bank (EDS), “Research Prospectus: A Vision for Sustainable Land Management Research in Central Asia. Multi-Country Partnership Framework Support Project on Sustainable Land Management Research,” ICARDA-Program Facilitation Unit, Tashkent, 2008.
 B. Qushimov, I. M. Ganiev, I. Rustamova, B. Haitov and K. R. Islam, “Land Degradation by Agricultural Activities in Central Asia,” In: R. Lal, M. Suleymenov, B. A. Stewart, D. O. Hansen and P. Doraiswamy, Eds., Climate Change and Terrestrial Carbon Sequestration in Central Asia, Taylor & Francis, London, 2007, pp. 137-147.