[1] C. Argoff, “Mechanisms of Pain Transmission and Pharmacologic Management,” Current Medical Research Opinion, Vol. 27, No. 10, 2011, pp. 2019-2031.
http://dx.doi.org/10.1185/03007995.2011.614934
[2] C. G. García, H. F. Miranda, V. Noriega, F. Sierralta, L. Olavarría, R. Zepeda and J. C. Prieto, “Antinociception Induced by Atorvastatin in Different Pain Models,” Pharmacology Biochemistry and Behavior, Vol. 100, No. 1, 2011, pp. 125-129.
http://dx.doi.org/10.1016/j.pbb.2011.08.007
[3] H. F. Miranda, V. Noriega, L. Olavarría, R. J. Zepeda, F. Sierralta and J. C. Prieto, “Antinociception and Anti-Inflamation Induced by Simvastatin in Algesiometric Assays in Mice,” Basic & Clinical Pharmacology & Toxicology, Vol. 109, No. 6, 2011, pp. 438-442.
http://dx.doi.org/10.1111/j.1742-7843.2011.00746.x
[4] M. M. Ghaisas, P. R. Dandawatew, S. A. Zawar, Y. S. Ahire and S. P. Gandhi, “Antioxidant, Antinociceptive and Antiinflammatory Activities of Atorvastatin and Rosuvastatin in Various Experimental Models,” Inflammopharmacology, Vol. 18, No. 4, 2010, pp. 169-177.
http://dx.doi.org/10.1007/s10787-010-0044-6
[5] M. Landsberger, F. Jantzen, S. Konemann and S. B. Felix, “Blockade of Geranylgeranylation by Rosuvastatinupregulatesenos Expression in Human Venous Endothelial cells,” Biochemistry Biophysics Research Communications, Vol. 336, No. 4,2005, pp. 1005-1009.
http://dx.doi.org/10.1016/j.bbrc.2005.08.225
[6] P. Di Napoli, A. A.Taccardi, A. Grilli, M. A. De Lutiis, A. Barsotti, M. Felaco and R. De Caterina, “Chronic Treatment with Rosuvastatin Modulates Nitric Oxide Synthase Expression and Reduces Ischemia-Reperfusion Injury in Rat Hearts,” Cardiovascular Research, Vol. 66, No. 3, 2005, pp. 462-471.
http://dx.doi.org/10.1016/j.cardiores.2005.02.008
[7] S. P. Jones, M. F. Gibson, D. M. Rimmer, T. M. Gibson, B. R. Sharp and D. J. Lefer, “Preclinical and Clinical Pharmacology of Rosuvastatin, a New 3-Hydroxy-3-Methylglutaryl Coenzyme a Reductase Inhibitor,” American Journal of Cardiology, Vol. 87, No. 5, 2001, pp. 28B-32B.
http://dx.doi.org/10.1016/S0002-9149(01)01454-0
[8] P. Luccarini, A. Childereric, A. M. Gayder, D. Voisin and R. Dallel, “The Orofacial Formalin Test in the Mouse, a Behavioural Model for Studying Physiology and Modulation of Trigeminal Nociception,” Journal of Pain, Vol. 7, No. 12, 2006, pp. 908-914.
http://dx.doi.org/10.1016/j.jpain.2006.04.010
[9] M. C. Berenbaum, “What Is Synergism?” Pharmacology Review, Vol. 41, No. 2, 1989, pp. 93-141.
[10] H. F. Miranda, M. M. Puig, M. A. Romero and J. C. Prieto, “Effects of Tramadol and Dexketoprofen on Analgesia and Gastrointestinal Transit in Mice,” Fundamental and Clinical Pharmacology, Vol. 23, No. 1, 2009, pp. 81-88.
http://dx.doi.org/10.1111/j.1472-8206.2008.00636.x
[11] T. Santodomingo-Garzón, T. M. Cunha, W. A. Verri Jr, D. A. Valério, C. A. Parada and S. Poole, “Atorvastatin Inhibitits Inflammatory Hipernociception,” British Journal of Pharmacology, Vol. 149, No. 1, 2006, pp. 14-22.
http://dx.doi.org/10.1038/sj.bjp.0706836
[12] G. Weitz-Schmidt, “Statins as Anti-Inflammatory Agents,” Trends Pharmacological Sciences, Vol. 23, No. 10, 2002, pp. 482-487.
http://dx.doi.org/10.1016/S0165-6147(02)02077-1
[13] U. Schonbeck and P. Libby, “Inflammation, Immunity, and HMG-CoA Reductase Inhibitors: Statins as Antiinflamatory Agents?” Circulation, Vol. 109, No. 1, 2004, pp. 18-26.
[14] N. D. Eddy and D. Leimback, “Synthetic Analgesics. II. Dithyienylbutenyl-Amines and Dithyienylbutylamine,” Journal of Pharmacology and Experimental Therapeutics, Vol. 3, No. 2, 1953, pp. 544-547.
[15] D. L. Simmons, R. M. Botting and H. L. A. Timothy, “Cyclooxygenase Isozymes: The Biology of Prostaglandin Synthesis and Inhibition,” Pharmacology Review, Vol. 56, No. 3, 2004, pp. 387-437.
http://dx.doi.org/10.1124/pr.56.3.3
[16] K. Lee and E. Choi, “Analgesic and Anti-Inflammatory Effects of Liguria Fischeri Leaves in Experimental Animals,” Journal of Ethnopharmacology, Vol. 120, No. 1, 2008, pp. 103-107.
http://dx.doi.org/10.1016/j.jep.2008.07.038
[17] H. Wheeler-Aceto and A. Cowean, “Neurogenic and Tissue Mediated Components of Formalin Induced Edema: Evidence for Supraspinal Regulation,” Agents and Action, Vol. 34, No. 2, 1991, pp. 264-269.
http://dx.doi.org/10.1007/BF01993299
[18] J. Sawynok and A. Ried, “Modulation of Formalin-Induced Behaviors and Edema by Local and Systemic Administration of Dextromethorphan, Memantine and Ketamine,” European Journal of Pharmacology, Vol. 450, No. 1, 2002, pp. 153-162.
http://dx.doi.org/10.1016/S0014-2999(02)02119-2
[19] M. S. Elkind, “Inflammation, Atherosclerosis, and Stroke,” Neurologist, Vol. 12, No. 1, 2006, pp. 140-148.
http://dx.doi.org/10.1097/01.nrl.0000215789.70804.b0
[20] M. S. Kostapanos, H. J. Milionis and M. S. Elisaf, “An Overview of the Extra-Lipid Effects of Rosuvastatin,” Journal of Cardiovascular Pharmacology and Therapeutics, Vol. 13, No. 1, 2008, pp. 157-174.
http://dx.doi.org/10.1177/1074248408318628
[21] R. Kones, “Rosuvastatin, Inflammation, C-Reactive Protein, JUPITER, and Primary Prevention of Cardiovascular Disease—A Perspective,” Drug Design Development and Therapy, Vol. 4, No. 3, 2010, pp. 383-413.
http://dx.doi.org/10.2147/DDDT.S10812
[22] W. M. Schmidt, A. O. Spiel, B. Jilma, M. Wolzt and M. Müller, “In-Vivo Effects of Simvastatin and Rosuvastatin on Global Gene Expression in Peripheral Blood Leucocytes in a Human Inflammation Model,” Pharmacogenetics Genomics, Vol. 18, No. 1, 2008, pp. 109-120.
http://dx.doi.org/10.1097/FPC.0b013e3282f44d81
[23] X. Q. Shi, T. K. Lim, S. Lee, Y. Q. Zhao and J. Zhang, “Statins Alleviate Experimental Nerve Injury-Induced Neuropathic Pain,” Pain, Vol. 152, No. 5, 2011, pp. 1033-1043. http://dx.doi.org/10.1016/j.pain.2011.01.006
[24] J. V. Espluges, “NO as a Signalling Molecule in the Nervous System,” British Journal of Pharmacology, Vol. 135, No. 5, 2002, pp. 1079-1095.
http://dx.doi.org/10.1038/sj.bjp.0704569
[25] Y. Chen, M. K. Boettger, A. Reif, A. Schmitt, N. Uceyler and C. Sommer, “Nitric Oxide Synthase Modulates CFA-Induced Thermal Hyperalgesia through Cytokine Regulation in Mice,” Molecular Pain, Vol. 2, No. 1, 2010, pp. 6-13.
[26] J. Kopincová, A. Púzserová and I. Bernátová, “L-NAME in the Cardiovascular System—Nitric Oxide Synthase Activator?” Pharmacology Reports, Vol. 64, No. 3, 2012, pp. 511-520.