Keshava Navin Kumar Reddy, Murugulla Adharvana Chari^*, Mayur D. Khunt, V. V. N. K. V. Prasada Raju, Bojja Ramachandra Reddy, Vurimidi Himabindu, Ghanta Mahesh Reddy

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Research and Development, Integrated Product Development, Innovation Plaza, Dr. Reddy’s Laboratories Ltd., Bachupally, Quthubullapur, India.
Dr. MACS Bio-Pharma Pvt. Ltd., Western Hills, Kukatpally, Hyderabad, India.
Department of Chemistry, Institute of Science and Technology, J. N. T. University, Kukatpally, Hyderabad, India.
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Abstract: This process describes a novel technique for effective trapping of “Pd” metal through resins during the process development of L-valine, 2-[(2-amino-1,6-dihydro-6-oxo-9H-purin-9-yl) methoxy] ethyl ester, and mono hydrochloride known as a Valacyclovir hydrochloride (1). This technique is suitable for large-scale production of 1 and it is described here Pd metal trapping by using different resins.  

Keywords: Valacyclovir Hydrochloride; Antiviral Drug; N-Phthalimide-L-Valine Ester; Monomethylamine; Commercially Scalable Process; Less Cycle Time

Cite this paper: K. Reddy, M. Chari, M. Khunt, V. Raju, B. Reddy, V. Himabindu and G. Reddy, "New Method of Palladium Metal Trapping through Resins in Antiviral Drug: Valacyclovir HCl," International Journal of Organic Chemistry, Vol. 3 No. 4, 2013, pp. 251-255. doi: 10.4236/ijoc.2013.34036.

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