OJIM  Vol.3 No.4 , December 2013
Plasma cell pleocytosis in HSV-2 aseptic meningitis
Abstract: Plasma cell pleocytosis has been seen in cerebrospinal fluid (CSF) analysis of patients with multiple myeloma, multiple sclerosis, leukemia, west nile encephalitis and lymphoma. There also have been some anecdotal reports suggesting the presence of plasma cells in CSF as possible early indicator of WNV encephalitis. We describe a case of plasma cell pleocytosis in CSF due to HSV-2 meningitis, adding it to the list of possible etiologies for the same. 
Cite this paper: Kalia, R. and Hennessey, K. (2013) Plasma cell pleocytosis in HSV-2 aseptic meningitis. Open Journal of Internal Medicine, 3, 119-120. doi: 10.4236/ojim.2013.34026.

[1]   Johnson, R.J. (2011) Aseptic meningitis in adults. In: UpToDate, Basow, D.S., Ed., UpToDate, Waltham.

[2]   Carson, P.J., Steidler, T., Patron, R., Tate, J.M., Tight, R., Smego Jr., R.A. (2003) Plasma cell pleocytosis in CSF in patients with West Nile Virus encephalitis. Clinical Infectious Diseases, 37, e12-e15.

[3]   Cohen, J.I. (2011) Chapter 191. Enteroviruses and reoviruses. In: Longo, D.L., Fauci, A.S., Kasper, D.L., Hauser, S.L., Jameson, J.L., Loscalzo, J., Eds., Harrison’s Principles of Internal Medicine, 18e.

[4]   Parasuraman, T.V., Frenia, K. and Romero, J. (2001) Enteroviral meningitis. Cost of illness and considerations for the economic evaluation of potential therapies. Pharmacoeconomics, 19, 3-12.

[5]   Kupila, L., Vuorinem, T., Vainionpaa, R., Hukkanen, V., Marttila, R.J. and Kotilainen, P. (2006) Etiology of aseptic meningitis and encephalitis in an adult population. Neurology, 66, 75-80.

[6]   Landry, M.L., Greenwold, J. and Vikram, H.R. (2009) Herpes simplex type-2 meningitis: Presentation and lack of standardized therapy. American Journal of Medicine, 122, 688-689.