OJPed  Vol.3 No.4 , December 2013
Desmoid tumor in a laparotomy scar in a child: Case report and brief literature review
Abstract: Desmoid tumors are rare neoplasms arising at the site of any fascia. Although histologically benign, they can cause local infiltration and they also carry a risk of recurrence. We describe the case of an 11-year-old girl who presented with a desmoid tumor at the site of an old trauma, and we briefly review the literature of this lesion.
Cite this paper: Skondras, J. , Valioulis, P. , Papakonstantinou, D. , Economopoulos, N. , Sourla, A. and Zavras, N. (2013) Desmoid tumor in a laparotomy scar in a child: Case report and brief literature review. Open Journal of Pediatrics, 3, 386-390. doi: 10.4236/ojped.2013.34070.

[1]   Wu, C., Amini-Nik, S., Nadesan, P., et al. (2010) Aggressive fibromatosis (desmoid tumor) is derived from mesenchymal progenitor cells. Cancer Research, 70, 7690-7698. 1158/0008-5472.CAN-10-1656

[2]   Reitamo, J.J., Hayry, P., Nykyri, E., et al. (1982) The desmoid tumor. I. Incidence, sex-, ageand anatomical distribution in the Finnish population. American Journal of Clinical Pathology, 77, 665-673.

[3]   Bolke, E., Krasniqi, H., Lammering, G., et al. (2009) Chest wall and intrathoracic desmoid tumors: Surgical experience and review of the literature. European Journal of Medical Research, 14, 240-243.

[4]   Phillips, S.R., A’Hern, R. and Thomas, J.M. (2004) Aggressive fibromatosis of the abdominal wall, limbs and limb girdles. British Journal of Surgery, 91, 1624-1629.

[5]   Honeyman, J.N. and La Quaglia, M.P. (2012) Desmoids tumors in the pediatric population. Cancers, 4, 295-306.

[6]   Kulaylat, M.N., Karakousis, C.P., Keanay, C.M., et al. (1999) Desmoid tumor: A pleomorphic lesion. European Journal of Surgical Oncology, 25, 487-497.

[7]   Hayry, P., Reitamo, J.J., Totterman, S., et al. (1982) Desmoid tumor II. Analysis of factors possibly contributing to the etiology and growth behavior. American Journal of Clinical Pathology, 77, 674-680.

[8]   Müller, J. (1838) Uber den feinern Bau und die Formen der Krankhften Creschwülste. G. Reimer, Berlin, 80.

[9]   Macfarlane, J. (1832) In: Robertson, D., Ed., Clinical reports of the Surgical Practice of the Glasgow, Royal Infirmary, 63.

[10]   Sakorafas, G.H., Nissotakis, C. and Peros, G. (2007) Abdominal desmoids tumors. Surgical Oncology, 16, 131-142.

[11]   Reitamo, J.J., Scheinin, T.M. and Hayry, P. (1986) The desmoid syndrome: New aspects in the cause, pathogenesis and treatment of the desmoid tumour. American Journal of Surgery, 151, 230-237.

[12]   Friedl, W., Caspari, R., Sengteller, M., et al. (2001) Can APC mutation analysis contribute to therapeutic decisions in familial adenomatous polyposis? Gut, 48, 515-521. 10.1136/gut.48.4.515

[13]   Giarola, M., Wells, D., Mondini, P., et al. (1998) Mutations of adenomatous polyposis coli (APC) gene are uncommon in sporadic desmoid tumors. British Journal of Cancer, 78, 582-587. 10.1038/bjc.1998.544

[14]   Tejpar, S., Nollet, F., Li, C., et al. (1999) Predominance of beta-catenin mutations and beta-catenin dysrgeulation in sporadic aggressive fibromatosis (desmoids tumor). Oncogene, 18, 6615-6620.

[15]   Economou, A., Pitta, X., Andreadis, A., et al. (2011) Desmoid tumor of the abdominal wall: A case report. Journal of Medical Case Reports, 5, 326.

[16]   Casillas, J., Sais, G.J., Greve, J.L., et al. (1991) Imaging of intraand extra abdominal desmoid tumors. Radiographics, 11, 959-968.

[17]   Brasfield, R.D. and Das Gupta, T.K. (1969) Desmoid tumors of the anterior abdominal wall. Surgery, 65, 241-246.

[18]   Weiss, S.W. and Goldblum, J.R. (2001) Fibromatoses. In: Enzinger and Weiss’s Soft Tumors, Vol. 4, Mosb, St. Louis, 309-346.

[19]   Stoeckle, E., Coindre, J.M., Longy, M., et al. (2009) A critical analysis of treatment in desmoids tumors: A review of a series of 106 cases. European Journal of Surgical Oncology, 35, 129-134.

[20]   Faulkner, L.B., Hajdu, S.I., Kher, U., et al. (1995) Pediatric desmoids tumor > retrospective analysis of 63 cases. Journal of Clinical Oncology, 13, 2813-2818.

[21]   Oudot, C., Orbach, D., Minard-Colin, V., et al. (2012) Desmoid fibromatosis in pediatric patients: Management based on a retrospective analysis of 59 patients and a review of the literature. Sarcoma, 2012, 475202.

[22]   Honeyman, J., Theilen, T.M., Knowles, M.E., et al. (2013) Desmoid fibromatosis in children and adolescents: A conservative approach to management. Journal of Pediatric Surgery, 48, 62-66.

[23]   Berardi, R.S. and Canlas, M. (1973) Desmoid tumor and laparotomy scars. International Surgery, 58, 254-256.

[24]   Overhaus, M., Decker, P., Fischer, H.P., et al. (2003) Desmoid tumor of the abdominal wall. World Journal of Surgical Oncology, 1, 11-15.

[25]   Wanjeri, J.K. and Opeya, C.J. (2011) A massive abdominal wall desmoids tumor occurring in a laparotomy scar: A case report. World Journal of Surgical Oncology, 9, 35. 1186/1477-7819-9-35

[26]   Warren, S. (1943) Minimal criteria required to prove causation of traumatic or occupational neoplasms. Annals of Surgery, 117, 585-595.

[27]   Urist, MR. (1957) Trauma and neoplasm: Report of case of desmoids tumor following simple fracture of the radius and ulna. American Journal of Surgery, 93, 682-688.

[28]   De Clan, F., Delay, E., Rudigoz, R.C., et al. (1999) Desmoid tumor arising in a Cesarean section scar during pregnancy: Monitoring and management. Gynecologic Oncology, 75, 145-148.

[29]   Patrick, L.E., O’Shea, P., Simoneaux, S.F., et al. (1996) Fibromatoses of childhood: The spectrum of radiographic findings. American Journal of Roentgenology, 166, 163-169. 2214/ajr.166.1.8571869

[30]   Sharma, A., Ngan, B.Y., Sandor, G.K.B., et al. (2008) Pediatric aggressive fibromatosis of the head and neck: A 20-year retrospective review. Journal of Pediatric Surgery, 43, 1596-1604.

[31]   Schmidt, D. and Harms, D. (1985) Fibromatosis of infancy and childhood-Histology and ultrastructure and clinicopathologic correlation. Kinderchir, 40, 40-46.

[32]   Meazza, C., Bisogno, G., Gronchi, A., et al. (2010) Aggressive fibromatosis in children and adolescents: The Italian experience. Cancer, 116, 233-240.

[33]   Ayala, A.G., Ro, J.Y., Goepfert, H., et al. (1986) Desmoid fibromatosis: A clinicopathologic study of 25 children. Seminars in Diagnostic Pathology, 3, 138-150.

[34]   Buitendijk, S., van de Ven, C.P., Dumans, T.G., et al. (2005) Pediatric aggressive fibromatosis: A retrospective analysis of 13 cases and review of the literature. Cancer, 104, 1090-1099.

[35]   Rao, B.N., Horowitz, M.E., Rapala, M., et al. (1987) Challenges in the treatment of childhood fibromatosis. Archives of Surgery, 122, 1296-1298. 01400230082015

[36]   Spiegel, D.A., Dormans, J.P., Meyer, J.S., et al. (1998) Aggressive fibromatosis from infancy to adolescence. Journal of Pediatric Orthopaedics, 19, 176-178.

[37]   Merchant, T.E., Nguyen, D. and Walter, A.W. (2000) Long-term results with radiation therapy for pediatric desmoids tumors. International Journal of Radiation Oncology*Biology*Physics, 47, 1267-1271.

[38]   Lackner, H., Urban, C., Kerbl, R., et al. (1997) Noncyotoxic drugs therapy in children with unresectable desmoid tumors. Cancer, 80, 334-340. (19970715)80:2<334::AID-CNCR22>3.0.CO;2-U

[39]   Chugh, R., Wathen, J.K., Patel, S.R., et al. (2010) Efficacy of imatinib in aggressive fibromatosis: Results of a phase II multicenter Sarcoma Alliance for Research through Collaboration (SARC). Clinical Cancer Research, 16, 4884-4891.

[40]   Bisogno, G., Tagarelli, A., Stramare, R., et al. (2013) Hydroxyurea treatment can avoid the need for aggressive surgery in pediatric fibromatosis. Journal of Pediatric Hematology/Oncology, 35, e171-e173.