GSC  Vol.1 No.1 , February 2011
The Synergy of Combined Use of DMSO and Bronsted Acid (Ionic Liquid) as a Catalyst Part I: Efficient Niementowski Synthesis of Modified Quinazolinones
ABSTRACT
A new rapid and versatile approach using Ionic liquid/DMSO as a chemical reagent for the synthesis of fused heterocyclic compounds in a highly efficient way is described. This method offers the advantages of proceeding in neutral conditions, giving high to excellent isolated yields (83–92%) for Niementowski synthesis with easy workup procedure. The inherent Bronsted acidity of ionic liquid and high polarity of both IL and DMSO resulted in a significant enhancement in the reaction rate.

Cite this paper
nullM. Kathiravan, R. Jalnapurkar, T. Chitre, R. Tamboli and K. Srinivasan, "The Synergy of Combined Use of DMSO and Bronsted Acid (Ionic Liquid) as a Catalyst Part I: Efficient Niementowski Synthesis of Modified Quinazolinones," Green and Sustainable Chemistry, Vol. 1 No. 1, 2011, pp. 12-18. doi: 10.4236/gsc.2011.11003.
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