OJAppS  Vol.3 No.7 , November 2013
Efficacy of Different Concentrations of Aloe chabaudii Leaf Gel as a Substitute for a Sulfonamide for the Control of Avian Coccidiosis
Abstract: The objective of this study was to investigate the effectiveness of Aloe chabaudii schonland juice as a potential substitute of sulphonamide drugs and to measure its effects when administered at different concentrations in the control of avian coccidiosis. 30 cobb and 500 broiler chickens were used for the experiment. The broilers were randomised into six groups of five birds each and the groups were assigned to six treatments in a Complete Randomised Design (CRD). Four of the groups were given any one of the following treatments, different concentrations of Aloe (weight/volume: 10%, 20% and 30%) and a sulphonamide. There was a control group which was not given a treatment and one cohort group which was neither infected nor treated. At two weeks of age, 25 of the birds were infected with coccidia via drinking water using infected chicken fecal matter, while the remaining five birds were left uninfected. Infection proceeded for 1 week and after the infection period, fecal oocysts were counted from each individual bird using the McMaster technique. Treatments started one day after the infection and continued for one week after 20 gram samples of fecal matter were taken from each bird per treatment and oocysts were counted. After oocyst counting, all birds were slaughtered and lesion scoring was done on the intestines using the Johnson and Reid technique. Data was analysed for oocysts count in different treatments, fecal egg count reduction, relative risk of coccidiosis and the effectiveness of Aloe concentrations as a substitute for a commercial sulphonamide. The results showed that the concentrations of Aloe used in the experiment were not effective as compared to the sulphonamide in controlling coccidiosis as the fecal egg reduction was below 90% for all concentrations. The relative risk of coccidiosis infection in the farm was found to be 100%, meaning that coccidiosis is a disease of economic importance at the farm. However, there was a reduction in the fecal oocyst count with increase in Aloe juice concentration to control coccidiosis, though this could not be compared to sulphonamide (ESB3) which was more effective (p < 0.05). This study has shown that there is potential for use of Aloe chabaudii leaf gel as a chemotherapeutic though much research is needed to determine absolute concentrations which will make it comparable to commercially available drugs in terms of efficacy.
Cite this paper: M. Sungirai, M. Mucheni and L. Masaka, "Efficacy of Different Concentrations of Aloe chabaudii Leaf Gel as a Substitute for a Sulfonamide for the Control of Avian Coccidiosis," Open Journal of Applied Sciences, Vol. 3 No. 7, 2013, pp. 430-435. doi: 10.4236/ojapps.2013.37053.

[1]   H. D. Chapman, “Origins of Coccidiosis Research in the Fowl—The First Fifty Years,” Avian diseases, Vol. 47, No. 1, 2003, pp. 1-20.

[2]   C. T. Gadzirayi, J. F. Mupangwa and E. Mutandwa, “Effectiveness of Aloe excelsa in Controlling Coccidiosis in Broilers,” Journal of Sustainable Development in Africa, Vol. 7, 2005, pp. 74-80.

[3]   A. Bassetti and S. Sala, “The Great Aloe Book,” 1st Edition (USA), Zuccari Editions, 2005, pp. 47-51.

[4]   F. R. Durrani, S. Ullah, N. Chand, Z. Durrani, and S. Akhtar, “Using Aqeous Extract of Aloe Gel as Anticoccidial and Immunostimulant Agent in Broiler Production,” Sarhad Journal of Agriculture, Vol. 24, No. 4, 2008, pp. 665-670.

[5]   M. Mwale, E. Bhebhe, M. Chimonyo and T. E. Halimani, “Use of Herbal Plants in Poultry Health Management in the Mushagashe Small-Scale Commercial Farming Area in Zimbabwe,” International Journal of Applied Research in Veterinary Medicine, Vol. 3, No. 2, 2005, pp. 163-170.

[6]   D. P. Conway and M. E. McKenzie, “Poultry Coccidiosis: Diagnostic and Testing Procedures,” Wiley-Blackwell, Hoboken, 2007.

[7]   J. Johnson and W. M. Reid, “Anticoccidial Drugs: Lesion Scoring Techniques in Battery and Floor-Pen Experiments with Chickens,” Experimental Parasitology, Vol. 28, No. 1, 1970, pp. 30-36.

[8]   D. Yim, S. S. Kang, D. W. Kim, S. H. Kim, H. S. Lillehoj and W. Min, “Protective Effects of Aloe vera Based Diets in Eimeria maxima Infected Broiler Chickens,” Experimental Parasitology, Vol. 127, No. 1, pp. 2011, pp. 322-325.

[9]   J. H. Hamman, “Composition and Applications of Aloe vera Leaf Gel,” Molecules, Vol. 13, No. 8, 2008, pp. 1599-1616.

[10]   S. Shane, “Controlling Coccidiosis: Current Practice, Future Choices,” WATT Poultry USA, Vol. 9, No. 5, 2008, pp. 32-37.

[11]   M. De Gussem, “Coccidiosis in Poultry: Review on Diagnosis, Control, Prevention and Interaction with Overall Gut Health,” Proceedings of the 16th European Symposium on Poultry Nutrition, Strasbourg, 26-30 August, 2007, pp. 253-261.

[12]   R. K. Waihenya, M. M. A. Mtambo, G. Nkwengulila and U. M. Minga, “Efficacy of Crude Extract of Aloe Secundiflora against Salmonella Gallinarum in Experimentally Infected Free-Range Chickens in Tanzania,” Journal of Ethnopharmacology, Vol. 79, No. 3, 2002, pp. 317-323.

[13]   W. H. Ott, “Coccidiosis: Experimental Designs Involving Drug Mixtures,” Experimental Parasitology, Vol. 28, No. 1, 1970, pp. 81-86.