JCDSA  Vol.3 No.3 B , November 2013
Effectiveness of a Broad-Spectrum Sunscreen in the Prevention of Melasma in Asian Pregnant Women

Chloasma, or melasma, is a commonly acquired pigmentary disorder among Asian women. It may be considered as a physiological change during pregnancy. The incidence in Asian women is higher than that in other ethnic groups but further epidemiologic data are needed. There are very few studies related to the benefits of sunscreens to prevent this dermatosis. The aim of this study was to assess the effectiveness of a broad-spectrum sunscreen in the prevention of melasma in Korean pregnant women. We tested the effectiveness and tolerance of a sunscreen product (SPF 50+, UVA-PF 30) during a 12-month clinical trial including 220 Korean parturients with skin type III and IV. 217 women completed the study. Only 3 (1%) of the study population developed melasma, which was mild (MASI grade between 1.2 and 2.7). In addition, the clinical effectiveness of the evaluated sunscreen was judged good to excellent by the majority of study participants and by the research dermatologists. The excellent tolerance of the sunscreen under evaluation was confirmed “good” to “excellent” in 95% and 97% of cases. This study clearly demonstrates that this broad-spectrum sunscreen is well tolerated and effective in the prevention of melasma in Korean pregnant women. Although treatment remains elusive, prevention is possible.

Cite this paper: S. Seité and S. Park, "Effectiveness of a Broad-Spectrum Sunscreen in the Prevention of Melasma in Asian Pregnant Women," Journal of Cosmetics, Dermatological Sciences and Applications, Vol. 3 No. 3, 2013, pp. 4-7. doi: 10.4236/jcdsa.2013.33A2002.

[1]   M. Jimbow and K. Jimbow, “Pigmentary Disorders in Oriental Skin,” Clinics in Dermatology, Vol. 7, No. 2, 1989, pp. 11-27.

[2]   J. H. Chung, “Photoaging in Asians,” Photodermatology, Photoimmunology & Photomedicine, Vol. 19, No. 3, 2003, pp. 109-121.

[3]   S. G. Ho and H. H Chan, “The Asian Dermatologic Patient: Review of Common Pigmentary Disorders and Cutaneous Diseases,” American Journal of Clinical Dermatology, Vol. 10, No. 3, 2009, pp. 153-168.

[4]   R. Wang, et al., “Prevalence of Melasma in Chinese Han and Chinese Yi: A Survey in Liangshan Distric,” The Chinese Journal of Dermatovenereology, Vol. 6, 2010, pp. 546-548.

[5]   A. Taylor, M. Pawaskar, S. L. Taylor, R. Balkrishnan and S. R. Feldman, “Prevalence of Pigmentary Disorders and Their Impact on Quality of Life: A Prospective Cohort Study,” Journal of Cosmetic Dermatology, Vol. 7, No. 3, 2008, pp. 164-168.

[6]   M. Perez, J. Luke and A. Rossi, “Melasma in Latin Americans,” Journal of Drugs in Dermatology, Vol. 10, No. 5, 2011, pp. 517-523.

[7]   H. Lakhdar, K. Zouhair, K. Khadir, A. Essari, A. Richard, S. Seité and A. Rougier, “Evaluation of the Effectiveness of an External Broad-Spectrum Sunscreen in the Prevention of Chloasma in Pregnant Women,” Journal of the European Academy of Dermatology and Venereology, Vol. 21, No. 6, 2007, pp. 738-742.

[8]   K. Khadir, S. Amal, F. Hali, F. Nejjam and H. Lakhdar, “Les Signes Dermatologiques Physiologiques de la Grossesse,” Annales de Dermatologie et de Venereologie, Vol. 126, 1999, pp. 15-19 [in French].

[9]   T. B. Fitzpatrick, “The Validity and Practicability of Sun-Reactive Skin Types I through VI,” Archives of Dermatology, Vol. 124, No. 6, 1988, pp. 869-887. 0015008

[10]   J. H. Chung, W. S. Koh and J. I. Youn, “Relevance of Skin Phototyping to a Korean Population,” Clinical and Experimental Dermatology, Vol. 19, 1994, pp. 476-478.

[11]   S. B. Park, D. H. Suh and J. I. Youn, “Reliability of Self-Assessment in Determining Skin Phototype for Korean Brown Skin,” Photodermatology, Photoimmunology & Photomedicine, Vol. 14, No. 5-6, 1998, pp. 160-163.

[12]   C. K. Kimbrough-Green, C. E. Griffiths, L. J. Finkel, T. A. Hamilton, S. M. Bulengo-Ransby, C. N. Ellis and J. J. Voorhees, “Topical Retinoic Acid (Tretinoin) for Melasma in Black Patients. A Vehicle-Controlled Clinical Trial,” Archives of Dermatology, Vol. 130, No. 6, 1994, pp. 727-733. archderm.1994.01690060057005

[13]   A. G. Pandya, L. S. Hynan, R. Bhore, F. C. Riley, I. L. Guevara, P. Grimes, J. J. Nordlund, M. Rendon, S. Taylor, R. W. Gottschalk, N. G. Agim and J. P. Ortonne, “Reliability Assessment and Validation of the Melasma Area and Severity Index (MASI) and a New Modified MASI Scoring Method,” Journal of the American Academy of Dermatology, Vol. 64, No. 1, 2011, pp. 78-83. j.jaad.2009.10.051

[14]   J. P. Ortonne, I. Arellano, M. Berneburg, T. Cestari, H. Chan, P. Grimes, D. Hexsel, S. Im, J. Lim, H. Lui, A. Pandya, M. Picardo, M. Rendon, S. Taylor, J. P. Van Der Veen and W. Westerhof, “A Global Survey of the Role of Ultraviolet Radiation and Hormonal Influences in the Development of Melasma,” Journal of the European Academy of Dermatology and Venereology, Vol. 23, No. 11, 2009, pp. 1254-1262.