OJOG  Vol.3 No.9 A , November 2013
Periarterial stem villous edema is associated with hypercoiled umbilical cord and stem obliterative endarteritis
Author(s) Jerzy Stanek
ABSTRACT

To assess clinicopathologic correlations of a novel placental lesion featuring a distinct ring-like periarterial edema of stem villi (PASE). A retrospective case-control statistical comparison (Yates χ2 or analysis of variance) of 30 clinical and 41 placental features of 100 consecutive placentas with PASE and 100 gestational age-matched cases without PASE, extracted from 2403 placentas from high-risk pregnancies signed out by the author since year 2006. The PASE was seen in 4.2% of placentas, average gestational age 35.9 weeks (range, 24 - 42 weeks). Frequencies of stem obliterative endarteritis and hypercoiled umbilical cord (coiling index > 0.3) were 23% vs 5% (p = 0.005), and 20% vs 9% (p = 0.04) in the study group and comparative group, respectively. There were no statistically significant differences (p > 0.05) between the groups in clinical or other placental variables. The PASE may be linked to chronically abnormal blood flow in umbilical cord arteries and their stem branches and may be a histological placental sign of non-obliterative umbilical cord compromise.


Cite this paper
Stanek, J. (2013) Periarterial stem villous edema is associated with hypercoiled umbilical cord and stem obliterative endarteritis. Open Journal of Obstetrics and Gynecology, 3, 9-14. doi: 10.4236/ojog.2013.39A002.
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