M. Jemal and Y. Q. Xia, “LC-MS Development Strategies for Quantitative Bioanalysis,” Current Drug Metabolism, Vol. 7, No. 5, 2006, pp. 491-502.
 M. Holcapek, L. Kolárová and M. Nobilis, “High-Performance Liquid Chromatography-Tandem mass Spectrometry in the Identification and Determination of Phase I and Phase II Drug Metabolites,” Analytical and Bioanalytical Chemistry, Vol. 391, No. 1, 2008, pp. 59-78.
 Y. Hsieh and W. A. Korfmacher, “Increasing Speed and Throughput When Using HPLC-MS/MS Systems for Drug Metabolism and Pharmacokinetic Screening,” Current Drug Metabolism, Vol. 7, No. 5, 2006, pp. 479-489.
 W. Korfmacher, “High-Resolution Mass Spectrometry Will Dramatically Change Our Drug-Discovery Bioanalysis Procedures,” Bioanalysis, Vol. 3, No. 11, 2011, pp. 1169-1171.
 W. A. Korfmacher, “Principles and Applications of LC-MS in New Drug Discovery,” Drug Discovery Today, Vol. 10, No. 20, 2005, pp. 1357-1367.
 R. Ramanathan, M. Jemal, S. Ramagiri, Y. Q. Xia, W. G. Humpreys, T. Olah and W. A. Korfmacher, “It Is Time for a Paradigm Shift in Drug Discovery Bioanalysis: From SRM to HRMS,” Journal of Mass Spectrometry, Vol. 46, No. 6, 2011, pp. 595-601.
 R. Ramanathan and W. Korfmacher, “The Emergence of High Resolution Mass Spectrometry as the Premier Analytical Tool in the Pharmaceutical Bioanalysis Arena,” Bioanalyis, Vol. 4, 2012, pp. 501-503.
 R. Ramanathan, R. Zhong, N. Blumenkrantz, S. K. Chowdhury and K. B. Alton, “Response Normalized Liquid Chromatography Nanospray Ionization Mass Spectrometry,” Journal of the American Society for Mass Spectrometry, Vol. 18, No. 10, 2007, pp. 1891-1899.
 L. K. Kamdem, D. A. Flockhart and Z. Desta, “In Vitro Cytochrome P450-Mediated Metabolism of Exemestane,” Drug Metabolism and Disposition, Vol. 39, No. 1, 2011, pp. 98-105.
 D. Liu, X. Zheng, Y. Tang, J. Zi, Y. Nan, S. Wang, C. Xiao, J. Zhu and C. Chen, “Metabolism of Tanshinol Borneolester in Rat and Human Liver Microsomes,” Drug Metabolism and Disposition, Vol. 38, No. 9, 2010, pp. 1464-1470.
 M. Shebley, U. M. Kent, D. P. Ballou and P. F. Hollenberg, “Mechanistic Analysis of the Inactivation of Cytochrome P450 2B6 by Phencyclidine: Effects on Substrate Binding, electron Transfer, and Uncoupling,” Drug Metabolism and Disposition, Vol. 37, No. 4, 2009, pp. 745-752. http://dx.doi.org/10.1124/dmd.108.024661
 R. Ramanathan, J. L. Josephs, M. Jemal, M. Arnold and W. G. Humphreys, “Novel MS Solutions Inspired by MIST,” Bioanalyis, Vol. 2, No. 7, 2010, pp. 1291-1313.
 Y. Yang, M. F. Grubb, C. E. Luk, W. G. Humphreys and J. L. Josephs, “Quantitative Estimation of Circulating Metabolites without Synthetic Standards by Ultra-High-Performance Liquid Chromatography/High Resolution Accurate Mass Spectrometry in Combination with UV Correction,” Rapid Communications in Mass Spectrometry, Vol. 25, No. 21, 2011, pp. 3245-3251.
 USFDA, “Guidance for Industry: Safety Testing of Drug Metabolites,” 2008, pp. 1-25.
 F. Cuyckens, L. I. Balcaen, K. De Wolf, B. De Samber, C. Van Looveren, R. Hurkmans and F. Vanhaecke, “Use of the Bromine Isotope Ratio in HPLC-ICP-MS and HPLC-ESI-MS Analysis of a New Drug in Development,” Analytical and Bioanalytical Chemistry, Vol. 390, No. 7, 2008, pp. 1717-1729.
 U. P. Dahal, J. P. Jones, J. A. Davis and D. A. Rock, “Small Molecule Quantification by Liquid Chromatography-Mass Spectrometry for Metabolites of Drugs and Drug Candidates,” Drug Metabolism and Disposition, Vol. 39, No. 12, 2011, pp. 2355-2360.
 R. Espina, L. Yu, J. Wang, Z. Tong, S. Vashishtha, R. Talaat, J. Scatina and A. Mutlib, “Nuclear Magnetic Resonance Spectroscopy as a Quantitative Tool To Determine the Concentrations of Biologically Produced Metabolites: Implications in Metabolites in Safety Testing,” Chemical Research in Toxicology, Vol. 22, No. 2, 2009, pp. 299-310. http://dx.doi.org/10.1021/tx800251p
 S. Schadt, L. Z. Chen and D. Bischoff, “Evaluation of Relative LC/MS Response of Metabolites to Parent Drug in LC/Nanospray Ionization Mass Spectrometry: Potential Implications in MIST Assessment,” Journal of Mass Spectrometry, Vol. 46, No. 12, 2011, pp. 1281-1286.
 D. A. Smith and R. S. Obach, “Metabolites: Have We MIST out the Importance of Structure and Physicochemistry?” Bioanalysis, Vol. 2, No. 7, 2010, pp. 1223-1233.
 K. Vishwanathan, K. Babalola, J. Wang, R. Espina, L. Yu, A. Adedoyin, R. Talaat, A. Mutlib and J. Scatina, “Obtaining Exposures of Metabolites in Preclinical Species through Plasma Pooling and Quantitative NMR: Addressing Metabolites in Safety Testing (MIST) Guidance without Using Radiolabeled Compounds and Chemically Synthesized Metabolite Standards,” Chemical Research in Toxicology, Vol. 22, No. 2, 2009, pp. 311-322.
 P. Wright, Z. Miao and B. Shilliday, “Metabolite Quantitation: Detector Technology and MIST Implications,” Bioanalyis, Vol. 1, No. 4, 2009, pp. 831-845.
 C. Yu, C. L. Chen, F. L. Gorycki and T. G. Neiss, “A Rapid Method for Quantitatively Estimating Metabolites in Human Plasma in the Absence of Synthetic Standards Using a Combination of Liquid Chromatography/Mass Spectrometry and Radiometric Detection,” Rapid Communications in Mass Spectrometry, Vol. 21, No. 4, 2007, pp. 497-502. http://dx.doi.org/10.1002/rcm.2863
 D. Zhang, N. Raghavan, T. Chando, J. Gambardella, Y. Fu, D. Zhang, S. Unger and W. G. Humphreys, “LC-MS/MS-Based Approach for Obtaining Exposue Estimates of Metabolites in Early Clinical Trials Using Radioactive Metabolites as Reference Standards,” Drug Metabolism Letters, Vol. 1, No. 4, 2007, pp. 293-298.
 M. Zhu, H. Zhang and W. G. Humphreys, “Drug Metabolite Profiling and Identification by High-Resolution Mass spectRometry,” The Journal of Biological Chemistry, Vol. 286, 2011, pp. 25419-25425.
 R. Ramanathan, N. Raghavan, S. N. Comezoglu and W. G. Humphreys, “A Low Flow Ionization Technique to Integrate Quantitative and Qualitative Small Molecule Bioanalysis,” International Journal of Mass Spectrometry, Vol. 301, No. 1-3, 2011, pp. 127-135.
 A. Ranasinghe, R. Ramanathan, M. Jemal, C. J. D’Arienzo, W. G. Humphreys and T. Olah, “Integrated Quantitative and Qualitative Workflow for In-Vivo Bioanalytical Support in Drug Discovery using Hybrid Q-TOF MS,” Bioanalyis, Vol. 4, No. 5, 2012, pp. 511-528.
 J. Schmidt, M. M. Meyer, I. Spector and S. R. Kass, “Infrared Multiphoton Dissociation Spectroscopy Study of Protonated p-Aminobenzoic Acid: Does Electrospray Ionization Afford the Aminoor Carboxy-Protonated ion?” The Journal of Physical Chemistry, Vol. 115, No. 26, 2011, pp. 7625-7632.
 M. Chang, Y. Li, R. Angeles, S. Khan, L. Chen, J. Kaplan and L. Yang, “Development of Methods to Monitor Ionization Modification from Dosing Vehicles and Phospholipids in Study Samples,” Bioanalysis, Vol. 3, No. 15, 2011, pp. 1719-1739.
 Y. Q. Xia, J. Lau, T. Olah and M. Jemal, “Targeted Quantitative Bioanalysis in Plasma Using Liquid Chromatography/High-Resolution Accurate Mass Spectrometry: An Evaluation of Global Selectivity as a Function of Mass Resolving Power and Extraction Window, with Comparison of Centroid and Profile moDes,” Rapid Communications in Mass Spectrometry, Vol. 25, No. 19, 2011, pp. 2863-2878.
 G. A. Valaskovic, L. Utley, M. S. Lee and J. T. Wu, “Ultra-Low Flow Nanospray for the Normalization of Conventional Liquid Chromatography/Mass Spectrometry through Equimolarrsesponse: Standard-Free Quantitative Estimation of Metabolite Levels in Drug Discovery,” Rapid Communications in Mass Spectrometry, Vol. 20, No. 7, 2006, pp. 1087-1096.