MNSMS  Vol.3 No.4 B , October 2013
The Influence of Sheath Solvent’s Flow Rate on the Quality of Electrospun Ethyl Cellulose Nanofibers
ABSTRACT

The present research investigates the influence of sheath solvent’s flow rate on the quality of electrospun ethyl cellulose (EC) nanofibers using a modified coaxial process. With 24 w/v % EC in ethanol as electrospinnable core fluid and ethanol as sheath fluid, EC nanofibers generated under different sheath flow rates were generated from the modified processes. FESEM observations demonstrate that the modified process is effective in preventing the clogging of spinneret for a smooth electrospinning. The key for the modified coaxial process is the reasonable selection of a sheath flow rate matching the drawing process of core EC fluid during the electrpospinning. The EC nanofibers’ diameters (D, nm) could be manipulated through the sheath-to-core flow rate ratio (f) as D = 819-1651f (R= 0.9754) within a suitable range of 0 to 0.25. The present paper provides useful data for the implementation of the modified coaxial process controllably to obtain polymer nanofibers with high quality.


Cite this paper
D. Yu, X. Li, J. Ge, P. Ye and X. Wang, "The Influence of Sheath Solvent’s Flow Rate on the Quality of Electrospun Ethyl Cellulose Nanofibers," Modeling and Numerical Simulation of Material Science, Vol. 3 No. 4, 2013, pp. 1-5. doi: 10.4236/mnsms.2013.34B001.
References
[1]   L.Y. Huang, D. G. Yu, C. Branford-White and L. M. Zhu, “Sustained Release of Ethyl Cellulose Micro-particulate Drug Delivery Systems Prepared Using Electrospraying,” Journal of Materials Science, Vol. 47, No. 3, 2012, pp. 1372-1377. doi:10.1007/s10853-011-5913-x

[2]   L. Y. Huang, C. Branford-White, X. X. Shen, D. G. Yu and L. M. Zhu, “Time-engineeringed Biphasic Drug Release by Electrospun Nanofiber Meshes,” International Journal of Pharmaceutics, Vol. 436, No. 1-2, 2012, pp. 88-96. doi:10.1016/j.ijpharm.2012.06.058

[3]   D. G. Yu, G. R. Williams, X. Wang, J. H. Yang, X. Y. Li, W. Qian and Y. Li, “Polymer-based Nanoparticulate Solid Dispersions Prepared by a Modified Electrospraying Process,” Journal of Biomedical Science and Engineering, Vol. 4, No. 12, 2011, pp. 741-749. doi:10.4236/jbise.2011.412091

[4]   D. G. Yu, X. Wang, X. Y. Li, W. Chian, Y. Li and Y. Z. Liao, “Electrospun Biphasic Drug Release Polyvinylpyrrolidone/ ethyl Cellu-lose Core/sheath Nanofibers,” Acta Biomaterialia, Vol. 9, No. 3, 2013, pp. 5665-5672. doi: 10.1016/j.actbio.2012.10.021

[5]   D. G. Yu, X. Y. Li, X. Wang, W. Chian, Y. Z. Liao and Y. Li, “Zero-order Drug Release Cellulose Acetate Nanofibers Prepared Using Coaxial Electrospinning,” Cellulose, Vol. 20, No. 1, 2013, pp. 379-389. doi: 10.1007/s10570-012-9824-z

[6]   D. G. Yu, W. Chian, X. Wang, X. Y. Li, Y. Li and Y. Z. Liao, “Linear Drug Release Membrane Prepared by a Modified Coaxial Electrospinning Process,” Journal of Membrane Sciences, Vol. 428, No. 3, 2013, pp. 150-156. doi: 10.1016/j.memsci.2012.09.062

[7]   D. G. Yu, X. X. Shen, C. Branford-white, K. White, S. W. A. Bligh and L. M. Zhu, “Oral Fast-dissolving Drug Delivery Membranes Prepared from Electrospun Polyvinylpyrrolidone Ultrafine Fibers,” Nanotechnology, Vol. 20, No. 4, 2009, pp. 055104. doi:10.1088/0957-4484/20/5/055104

[8]   K. Kanjanapongkul, S. Wongsasulak and T. Yoovidhya, “Prediction of Clogging Time During Electrospinning of Zein Solution: Scaling Analysis and Experimental Verification,” Chemical Engineering Science, Vol. 65, No. 7, 2010, pp. 5217-5225. doi:10.1016/j.ces.2010.06.018

[9]   K. Kanjanapongkul, S. Wongsasulak and T. Yoovidhya, “Investigation and Prevention of Clogging during Electrospinning of Zein Solution,” Journal of Appllied Polymer Science, Vol. 118, No. 8, 2010, pp. 1821-1829. doi:10.1002/app.32499

[10]   D. G. Yu, L. M. Zhu, C. Branford-White, S. W. A. Bligh and K. White, “Coaxial Electrospinning with Organic Solvent for Controlling the Self-assembled Nanoparticle size,” Chemical Communications, Vol. 47, No. 4, 2011, pp. 1216-1218.doi:10.1039/c0cc03521a

[11]   D. G. Yu, C. Branford-White, N. P. Chatterton, K. White, L. M. Zhu, X. X. Shen and W. Nie, “Electrospinning of Concentrated Polymer Solutions,” Macromolecules, Vol. 43, No. 24, 2010, pp. 10743-10746. doi:10.1021/ma1024363

[12]   L. Y. Yeo and J. R. Friend, “Electrospinning Carbon Nanotube Polymer Composite Nanofiber,” Journal of Experimental Nanoscience, Vol. 2, No. 2, 2006, pp. 177-209.doi:10.1080/17458080600670015

 
 
Top