(1→3)-β-D-glucan from the inner cell wall of
Saccharomyces cerevisiae is considered a member of a class of drugs known as biological
response modifiers (BRM). However the glucan was an insoluble polysaccharide,
which could be the major barrier to the utilization of glucan. In this case,
the insoluble glucan was convent into a soluble form by four kind of
solubilizing processes. The yield, solubility, chemistry structure and
immunoprophylaxis efficacy of the soluble products were compared. Our date
suggest that urea has a significant effect on yield, and DMSO has a significant
effect on solubility. FT-IR spectra,
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