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 OJAS  Vol.3 No.4 , October 2013
No replicated association of the c.-312A > G in EDG1 with marbling in Niigata population of Japanese Black beef cattle
Abstract: Marbling, defined by the amount and the distribution of intramuscular fat and measured as beef marbling score (BMS), is an economically important trait of beef cattle in Japan. We recently reported that a single nucleotide polymorphism (SNP), namely, c.-312A > G, in the endothelial differentiation sphingolipid G-proteincoupled receptor, 1 (EDG1) gene was associated with the BMS level in the Japanese Black beef cattle population of Oita prefecture, with the G allele being associated with a high level of the BMS. Thus, the c.-312A > G SNP seems to be a candidate marker for marker-assisted selection. In this study, we investigated whether this association could be replicated in the Japanese Black beef cattle population of Niigata prefecture and analyzed the effect of the SNP genotypes on the carcass traits other than the BMS. No significant differences in the BMS level were detected among the genotypes of the c.-312A > G SNP in the Niigata Japanese Black beef cattle population. The SNP genotype had no significant effects on the carcass weight, rib eye area and rib thickness of the cattle population. These findings suggested that the association of the c.-312A > G SNP with the BMS level in the Japanese Black beef cattle population was not replicated in the Niigata population, and revealed no effects of the SNP genotype on the beef productivity in the Niigata population. Thus, we concluded that the c.-312A > G SNP is not useful for effective marker-assisted selection to increase meat quality and, additionally, meat productivity in Japanese Black beef cattle of Niigata prefecture.
Cite this paper: Tong, B. , Fuke, N. , Himizu, Y. , Katou, H. , Hatano, M. , Ohta, T. , Kose, H. and Yamada, T. (2013) No replicated association of the c.-312A > G in EDG1 with marbling in Niigata population of Japanese Black beef cattle. Open Journal of Animal Sciences, 3, 269-272. doi: 10.4236/ojas.2013.34040.
References

[1]   JMGA (1988) New beef carcass grading standards. Japan Meat Grading Association, Tokyo.

[2]   Busboom, J.R., Jeremiah, L.E., Gibson, L.L., Johnson, K.A., Gaskins, C.T., Reeves, J.J. and Wright, R.W.Jr. (1993) Effects of biological source on cooking and palatability attributes of beef produced for the Japanese market. Meat Science, 35, 241-258. http://dx.doi.org/10.1016/0309-1740(93)90054-L

[3]   Boylston, T.D., Morgan, S.A., Johnson, K.A., Busboom, J.R., Wright, R.W.Jr. and Reeves, J.J. (1995) Lipid content and composition of Wagyu and domestic breeds of beef. Journal of Agricultural and Food Chemistry, 43, 1202-1207. http://dx.doi.org/10.1021/jf00053a015

[4]   Matsuishi, M., Fujimori, M. and Okitani, A. (2001) Wagyu beef aroma in Wagyu (Japanese Black cattle) beef preferred by the Japanese over imported beef. Animal Science Journal, 72, 498-504. https://www.jstage.jst.go.jp

[5]   Liu, Y., Wada, R., Yamashita, T., Mi, Y., Deng, C.X., Hobson, J.P., Rosenfeldt, H.M., Nava, V.E., Chae, S.S., Lee, M.J., Liu, C.H., Hla, T., Spiegel, S. and Proia, R.L. (2000) Edg-1, the G protein-coupled receptor for sphingosine-1-phosphate, is essential for vascular maturation. Journal of Clinical Investigation, 106, 951-961. http://dx.doi.org/10.1172/JCI10905

[6]   Sasaki, Y., Nagai, K., Nagata, Y., Doronbekov, K., Nishimura, S., Yoshioka, S., Fujita, T., Shiga, K., Miyake, T., Taniguchi, Y. and Yamada, T. (2006) Exploration of genes showing intramuscular fat deposition-associated changes in musculus longissimus muscle. Animal Genetics, 37, 40-46. http://dx.doi.org/10.1111/j.1365-2052.2005.01380.x

[7]   Sasaki, Y., Yamada, T. and Miyake, T. (2006) Quantitative and molecular genetic approaches for the improvement of carcass traits in the Wagyu cattle. 8th World Congress on Genetics Applied to Livestock Production, Session no. 13-01. Minas Centro Convention Center, Belo Horizonte, Minas Gerais.

[8]   Yamada, T., Taniguchi, Y., Nishimura, S., Yoshioka, S., Takasuga, A., Sugimoto, Y. and Sasaki, Y. (2006) Radiation hybrid mapping of genes showing intramuscular fat deposition-associated expression changes in bovine musculus longissimus muscle. Animal Genetics, 37, 184-185. http://dx.doi.org/10.1111/j.1365-2052.2006.01426.x

[9]   Yamada, T., Itoh, M., Nishimura, S., Taniguchi, Y., Miyake, T., Sasaki, S., Yoshioka, S., Fujita, T., Shiga, K., Morita, M. and Sasaki, Y. (2009) Association of single nucleotide polymorphisms in the endothelial differentiation sphingolipid G-protein coupled receptor 1 gene with marbling in Japanese Black beef cattle. Animal Genetics, 40, 209-216. http://dx.doi.org/10.1111/j.1365-2052.2008.01822.x

[10]   Sasaki, Y., Miyake, T., Gaillard, C., Oguni, T., Matsumoto, M., Ito, M., Kurahara, T., Sasae, Y., Fujinaka, K., Ohtagaki, S. and Dougo, T. (2006) Comparison of genetic gains per year for carcass traits among breeding programs in the Japanese Brown and the Japanese Black cattle. Journal of Animal Science, 84, 317-323. http://www.journalofanimalscience.org

[11]   Watanabe, N., Yoshioka, S., Itoh, M., Satoh, Y., Furuta, M., Komatsu, S., Sumio, Y., Fujita, Y., Yamada, T. and Sasaki, Y. (2009) The G allele at the c.-312A>G SNP in the EDG1 gene associated with high marbling in Japanese Black cattle is at a low frequency in breeds not selected for marbling. Animal Genetics, 40, 575-582. http://dx.doi.org/10.1111/j.1365-2052.2009.01871.x

[12]   Yamada, T., Sasaki, S., Sukegawa, S., Miyake, T., Fujita, T., Kose, H., Morita, M., Takahagi, Y., Murakami, H., Morimatsu, F. and Sasaki, Y. (2009) Novel SNP in 5’ flanking region of EDG1 associated with marbling in Japanese Black beef cattle. Animal Science Journal, 80, 486-489. http://dx.doi.org/10.1111/j.1740-0929.2009.00665.x

[13]   Takasuga, A., Watanabe, T., Mizoguchi, Y., Hirano, T., Ihara, N., Takano, A., Yokouchi, K., Fujikawa, A., Chiba, K., Kobayashi, N., Tatsuda, K., Oe, T., Furukawa-Kuroiwa, M., Nishimura-Abe, A., Fujita, T., Inoue, K., Mizoshita, K., Ogino, A. and Sugimoto, Y. (2007) Identification of bovine QTL for growth and carcass traits in Japanese Black cattle by replication and identical-by-descent mapping. Mammalian Genome, 18, 125-136. http://dx.doi.org/10.1007/s00335-006-0096-5

 
 
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