Cite this paper
Noritomi, H. , Chiba, H. , Kikuta, M. and Kato, S. (2013) How can aprotic ionic liquids affect enzymatic enantioselectivity?. Journal of Biomedical Science and Engineering
, 954-959. doi: 10.4236/jbise.2013.610117
 Klibanov, A.M. (2001) Improving enzymes by using them in organic solvents. Nature, 409, 241-246.
 Noritomi, H., Sasanuma, A., Kato, S. and Nagahama, K. (2007) Catalytic properties of cross-linked enzyme crystals in organic media. Biochemical Engineering Journal, 33, 228-231. http://dx.doi.org/10.1016/j.bej.2006.10.024
 Noritomi, H., Almarsson, O., Barletta, G.L. and Klibanov, A.M. (1996) The influence of the mode of enzyme preparation on enzymatic enantioselectivity in organic solvents and its temperature dependence. Biotechnology and Bioengineering, 51, 95-99.
 Wescott, C.R., Noritomi, H. and Klibanov, A.M. (1996) Rational control of enzymatic enantioselectivity through solvation thermodynamics. Journal of the American Chemical Society, 118, 10365-10370.
 Kise, H., Hayakawa, A. and Noritomi, H. (1990) Protease-catalyzed synthetic reactions and immobilization-activation of the enzymes in hydrophilic organic solvents. Journal of Biotechnology, 14, 239-254.
 Kokorin, A. (2011) Ionic liquids: Applications and perspectives. InTech, Rijeka.
 Moniruzzaman, M., Nakashima, K., Kamiya, N. and Goto, M. (2010) Recent advances of enzymatic reactions in ionic liquids. Biochemical Engineering Journal, 48, 295-314. http://dx.doi.org/10.1016/j.bej.2009.10.002
 Noritomi, H., Nishida, S. and Kato, S. (2007) Protease-catalyzed esterification of amino acid in water-miscible ionic liquid. Biotechnology Letters, 29, 1509-1512.
 Noritomi, H., Suzuki, K., Kikuta, M. and Kato, S. (2007) Catalytic activity of α-chymotrypsin in enzymatic peptide synthesis in ionic liquids. Biochemical Engineering Journal, 47, 27-30.
 Kumar, A. and Venkatesu, P. (2012) Overview of the stability of α-chymotrypsin in different solvent media. Chemical Reviews, 112, 4283-4307.
 Fersht, A. (1999) Structure and mechanism in protein science: A guide to enzyme catalysis and protein folding. W. H. Freeman and Company, New York.
 Segel, I.H. (1993) Enzyme kinetics: Behavior and analysis of rapid equilibrium and steady-state enzyme systems. John Wiley & Sons, Inc., New York.
 Noritomi, H., Minamisawa, K., Kamiya, R. and Kato, S. (2011) Thermal stability of proteins in the presence of aprotic ionic liquids. Journal of Biomedical Science and Engineering, 4, 94-99.
 Zaks, A. and Klibanov, A.M. (1988) The effect of water on enzyme action in organic media. The Journal of Biological Chemistry, 263, 8017-8021.
 Klibanov, A.M. (1986) Enzymes that work in organic solvents. Chemtech, 16, 354-359.