FNS  Vol.4 No.11 , November 2013
Effect of Blended Rice Bran and Olive Oil on Cardiovascular Risk Factors in Hyperlipidemic Patients
Abstract: The present study was designed to evaluate the effectiveness of blended rice bran and olive oil on hyperlipidemic subjects. A total of 60 moderately hyperlipidemic patients (Total Cholesterol (TC) >200 mg/dl and/or Triglycerides (TG) >150 mg/dl) with an age range of 45 - 60 were selected from Mediciti Hospital of Ludhiana and were divided into two groups: Group A and Group B containing 30 subjects each. The subjects of Group B were given blended rice bran and olive oil for a time period of 45 days and were asked to continue with their routine eating and physical activity pattern. The subjects of Group A were kept on their regular cooking oil. The serum lipid values were assessed before and after the study. Additional parameters assessed included anthropometry, dietary fat intake and physical activity pattern. The results showed that there was an insignificant change in the average body mass index (BMI) of the subjects of Group B before (27.0 kg/m2) and after (26.9 kg/m2) the study respectively. Also, there was an insignificant change in the lipid levels of the subjects of Group B after the study. The levels of TC and LDL cholesterol decreased by 3.7 and 9.0 percent respectively. Whereas, the levels of TG and VLDL cholesterol increased by 9.5 percent in the subjects of Group B after the feeding trials. Further, systolic and diastolic blood pressure of the subjects of Group B reduced by 2.9 and 2.3 percent respectively. An insignificant change was observed in all the parameters of selected subjects. So, the present study recommends carrying out more long duration research studies to evaluate the effectiveness of this blended oil.
Cite this paper: M. Choudhary, K. Grover and J. Sangha, "Effect of Blended Rice Bran and Olive Oil on Cardiovascular Risk Factors in Hyperlipidemic Patients," Food and Nutrition Sciences, Vol. 4 No. 11, 2013, pp. 1084-1093. doi: 10.4236/fns.2013.411141.

[1]   K. S. Reddy, “The Emerging Epidemic of Cardiovascular Disease in India,” In: P. Shetty and C. Gopalan, Eds., Diet, Nutrition and Chronic Disease: An Asian Perspec tive, Smith-Gordon, Bedford, 1998, pp. 50-54.

[2]   S. A. Bhatnagar, K. P. Kumar, J. Hemavathy and G. A. Krishna, “Fatty Acid Composition, Oxidative Stability and Radical Scavenging Activity of Vegetable Oil Blends with Coconut Oil,” Journal of the American Oil Chem ists’ Society, Vol. 86, No. 10, 2009, pp. 991-999.

[3]   A. Kennedy, D. S. Menon and E. Suneetha, “Study on Effect of Rice Bran and Sunflower Oil Blend on Human Lipid Profile,” Indian Journal of Applied & Pure Biology, Vol. 25, No. 2, 2010, pp. 375-384.

[4]   N. Frank, M. F. Andrews, B. S. Elliott, J. Lew and C. R. Boston, “Effects of Rice Bran Oil on Plasma Lipid Con centrations, Lipoprotein Composition, and Glucose Dy namics in Mares,” Journal of Animal Science, Vol. 83, No. 11, 2005, pp. 2509-2518.

[5]   B. M. Siddique, A. Ahmed, H. M. Ibrahim, S. Hena, M. Rafatullah and A. K. Omar, “Physico-Chemical Proper ties of Blends of Palm Olein with Other Vegetable Oils,” Grasas Y Aceites, Vol. 61, No. 4, 2010, pp. 423-429.

[6]   N. H. Khan, S. J. Khan, S. Ali, K. Hussain, S. M. Alam and A. Habib, “Development of Some New Micronutrient Rich Blends of Edible Vegetable Oils,” Current Botany, Vol. 2, No. 5, 2011, pp. 16-19.

[7]   M. M. Most, R. Tulley, S. Morales and M. Lefevre, “Rice Bran Oil, Not Fiber, Lowers Cholesterol in Humans,” American Journal of Clinical Nutrition, Vol. 81, No. 1, 2005, pp. 64-68.

[8]   R. Kusum, H. Bommayya, P. Fayaz and H. D. Rama chandran, “Palm Oil and Rice Bran Oil: Current Status and Future Prospects,” International Journal of Plant Physiology and Biochemistry, Vol. 3, No. 8, 2011, pp. 125-132.

[9]   M. I. Covas, “Olive Oil and the Cardiovascular System,” Pharmacological Research, Vol. 55, No. 3, 2007, pp. 175-186.

[10]   R. Turner, N. Etienne and G. M. Alonso, “Antioxidant and Anti-Atherogenic Activities of Olive Oil Phenolics,” International Journal of Vitamin and Nutrition Research, Vol. 75, No. 1, 2005, pp. 61-70.

[11]   M. Choudhary, K. Grover and G. Kaur, “Fatty Acid Com position, Oxidative Stability, and Radical Scavenging Activity of Rice Bran Oil Blends,” International Journal of Food and Nutritional Sciences, Vol. 2, No. 1, 2013, pp. 33-43.

[12]   FAO, “Energy Costs of Activities,” In: Human Energy Requirements: Report of a Joint FAO/ WHO/UNU Expert Consultation, FAO Food and Nutrition Technical Report Series No. 1, FAO, Rome, 2004, pp. 92-96.

[13]   Indian Council of Medical Research, “Nutrient Require ments and Recommended Dietary Allowances for Indi ans,” National Institute of Nutrition, Hyderabad, 2010.

[14]   D. B. Jelliffe, “The Assessment of Nutritional Status of Community,” WHO, Geneva, 1966.

[15]   P. Fossati and L. Principle, “Qualitative Determination of Triglycerides in Serum or Plasma by Enzymatic DHBC Colorimetric Method,” Clinical Chemistry, Vol. 28, No. 10, 1982, p. 2077.

[16]   W. Richmond, “Qualitative Determination of Cholesterol in Serum or Plasma by Enzymatic Method,” Clinical Chemistry, Vol. 19, No. 12, 1973, p. 1350.

[17]   M. F. Lopes-Virella, P. Stone, S. Ellis and J. A. Cohwel, “Qualitative Determination of HDL-Cholesterol in Serum or Plasma by Phospotungstate Method,” Clinical Chemistry, Vol. 23, No. 5, 1977, p. 882.

[18]   W. T. Frieldwalds, R. I. Levy and D. S. Friedrickson, “Estimation of Plasma or Serum Low Density Lipoprotein Cholesterol Concentration without Use of Preparaline Ultracentrifuge,” Clinical Chemistry, Vol. 18, No. 6, 1972, p. 499.

[19]   R. Kuriyan, N. Gopinath, M. Vaz and V. A. Kurpad, “Use of Rice Bran Oil in Patients with Hyperlipidemia,” The National Medical Journal of India, Vol. 18, No. 6, 2005, pp. 292-296.

[20]   S. Johnson and N. Saikia, “Fatty Acids Profile of Edible Oils and Fats in India,” 2009, pp. 1-42.

[21]   U. Goyal, B. Sadana and S. Verma, “Contribution of Various Foods to Fat and Fatty Acids Intake among Urban and Semi-Urban Women of Punjab,” Journal of Human Ecology, Vol. 18, No. 3, 2005, pp. 217-220.

[22]   P. M. Vijaylaxmi, B. Kasturiba, K. R. Naik and U. Malagi, “Influence of Fats and Oils Intake on the Lipid Profile of Adults Belonging to Different Income Groups,” Karnataka Journal of Agricultural Sciences, Vol. 20, No. 1, 2007, pp. 112-114.

[23]   A. R. Kaur, M. Nagi and T. Gulati, “Lipid Profile in Re lation to Type and Adequacy of Fat Consumed by Adult Punjabi Males: A Case Study,” Journal of Research, Pun jab Agricultural University, Vol. 45, No. 1-2, 2008, pp. 91-95.

[24]   WHO Expert Consultant, “Appropriate Body-Mass Index for Asian Population and Its Implications for Policy and Intervention Strategies,” The Lancet, Vol. 363, No. 9403, 2004, pp. 157-163.

[25]   Y. Ma, W. Li, B. C. Olendzki, S. L. Pagoto, P. A. Mer riam, D. E. Chiriboga, J. A. Griffith, J. Bodenlos, Y. Wang and I. S. Ockene, “Dietary Quality 1 Year after Diagnosis of Coronary Heart Disease,” Journal of the American Dietetic Association, Vol. 108, No. 2, 2008, pp. 240-246.

[26]   Ghafoorunissa and K. Krishnaswamy, “Dietary Prescrip tions,” In: Diet and Heart Diseases, 2007, pp. 21-37.

[27]   A. Berger, D. Rein, A. Schafer, I. Monnard, G. Gremaud, P. Lambelet and C. Bertoli, “Similar Cholesterol-Lower ing Properties of Rice Bran Oil, with Varied Gamma Oryzanol, in Mildly Hypercholesterolemic Men,” Euro pean Journal of Nutrition, Vol. 44, No. 3, 2005, pp. 163-173.

[28]   E. Lopez-Huertas, “Health Effects of Oleic Acid and Long Chain Omega-3 Fatty Acids (EPA and DHA) En riched Milks. A Review of Intervention Studies,” Phar macological Research, Vol. 61, No. 3, 2010, pp. 200-207.

[29]   A. M.Stephens, L. L. Dean, J. P. Davis, J. A. Osborne and T. H. Sanders, “Peanuts, Peanut Oil, and Fat Free Peanut Flour Reduced Cardiovascular Disease Risk Factors and the Development of Atherosclerosis in Syrian Golden Hamsters,” Journal of Food Science, Vol. 75, No. 4, 2010, pp. 116-122.

[30]   H. S. Rissam, S. Kishore and N. Trehan, “Coronary Heart Disease in Young Indians—The Missing Link,” Indian Academy of Clinical Medicine, Vol. 2, No. 3, 2001, pp. 128-132.

[31]   C. Rukmini and T. C. Raghuram, “Nutritional and Bio chemical Aspects of the Hypolipidemic Action of Rice Bran Oil: A Review,” Journal of American College of Nutrition, Vol. 10, No. 6, 1991, pp. 593-601.

[32]   T. C. Raghuram and C. Rukmini, “Nutritional Signifi cance of Rice Bran Oil,” Indian Journal of Medical Research, Vol. 102, Special Issue, 1995, pp. 241-244.

[33]   AHA, “Cholesterol Ratio—American Heart Association,” 2004.