IJOC  Vol.3 No.3 , September 2013
Regioselective Direct Carboxylation of 2-Naphthol with Supercritical CO2 in the Presence of K2CO3
A direct regioselective preparation of 2-hydroxynaphthalene-6-carboxylic acid, a useful industrial intermediate of aro-matic polyester from 2-naphthol was conducted by use of excess amount of K2CO3 (10-fold molar to 2-naphthol) under supercritical CO2 at 10 MPa and 473 K. The obtained yield under this condition was ca. 20 mol% to 2-naphthol. The further investigations may provide an alternative process to the conventional Kolbe-Schmitt reaction, because of no use of strong alkali and recoverability of K2CO3. Theoretical explanation about the regioselectivity was achieved by means of DFT calculations.

Cite this paper
S. Furukawa, K. Otokawa, O. Sasaki, K. Nakayasu and T. Yamaguchi, "Regioselective Direct Carboxylation of 2-Naphthol with Supercritical CO2 in the Presence of K2CO3," International Journal of Organic Chemistry, Vol. 3 No. 3, 2013, pp. 210-213. doi: 10.4236/ijoc.2013.33028.
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