OJBD  Vol.3 No.3 , September 2013
SNPs and TFBS Associated with High Altitude Sickness*
ABSTRACT
The rSNPs for the genes AKT3 (rs4590656), EGLN1 (rs480902), eNOS3 (rs1007311), and VEGFA (rs699947, rs13207311, rs1570360, rs2010963) have been significantly associated with the physiological parameters in high altitude sickness Han or Tibetan Chinese patients at the Qinghai-Tibetan plateau. The alleles of each rSNP have been found to create unique transcriptional factor binding sites for transcription factors that affect the process of hypoxia gene expression in this high altitude hypoxia environment.

Cite this paper
N. Buroker, X. Ning, Z. Zhou, K. Li, W. Cen, X. Wu, W. Zhu, C. Ronald Scott and S. Chen, "SNPs and TFBS Associated with High Altitude Sickness*," Open Journal of Blood Diseases, Vol. 3 No. 3, 2013, pp. 85-93. doi: 10.4236/ojbd.2013.33018.
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