Background: Fatigue is often identified as weakness following muscular exertion in patients
with multiple sclerosis (MS) but may be associated with other physical,
cognitive and emotional symptoms. Objective:To develop a
Spanish language global impression of fatigue scales to evaluate symptoms of fatigue distinct from a particular disease. Methods:50 ambulatory patients
with MS attending a clinical institute in Argentina consented to participate in
this reliability study. The Spanish language version of the Clinical and
Patient Global Impressions of Fatigue (CGI-S-F and PGI-S-F) instruments were
administered with the Massachusetts General Hospital cognitive and physical
(MGH-CPFQ). Results: The CGI-S-F and
PGI-S-F scores were well correlated with each other (p < 0.00005). The mean CGI-S for fatigue was 2.28 ± 1.07 (SD)
and PGI-S for fatigue was 2.30 ± 1.16 (p =ns) reflecting
borderline to mild perception of fatigue. The total MGH-CPFQ was 16.68 ± 4.32.
Both CGI-S-F and PGI-S-F measures were correlated with the MGH-CPFQ:
CGI-Severity (r=0.632; p< 0.00005);
PGI-Severity (r=0.717; p< 0.00005). Conclusions: In this study, the Spanish language
versions of the CGI-S-F and PGI-S-F were reliable measures in an MS population and can be useful and easily
applied metrics in a busy clinical practice.
Cite this paper
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