Lichen Planopilaris is a Common Scarring Alopecia among Iraqi Population

Khalifa E.  Sharquie; Adil A.  Noaimi; Ammar F.  Hameed

doi:10.4236/jcdsa.2013.33A1005

Khalifa E. Sharquie, Adil A. Noaimi, Ammar F. Hameed

Abstract: Background: Scarring alopecia like discoid lupus erythematosus, lichenplanopilaris and scarring folliculitis are common skin problems where differentiations between them are often difficult in many cases. Objective: To report, study and evaluate cases of lichen planopilaris and characterize the different clinical points in favor of this disease. Patients and Methods: This case series descriptive study was done at Department of Dermatology-Baghdad Teaching Hospital from January 2010 to November 2012. Sixty seven patients were included where histological and dermatological examinations were carried out to all patients regarding all relevant points related to the disease. Punch biopsies were performed from ten patients for histopathological study. Results: The mean age of onset of the disease was 36.7 ± 5 years with a mean duration of the disease being 4.4 ± 3 years. The male to female ratio was 1.4:1. The characteristic lesions were pigmented scarring moth eaten alopecia surrounded by pigmented hyperkeratotic follicular papules involving mainly the fronto-vertical and parietal scalp. Conclusions: Lichen planopilaris is a common cause of scalp scarring alopecia in adult and it has many characteristic clinical features which can facilitate differentiation from other pathologic scalp conditions like discoid lupus erythematosus.

Keywords: Cicatricial Alopecia; Lichen Planopilaris; Moth Eaten Alopecia

Cite this paper: K. Sharquie, A. Noaimi and A. Hameed, "Lichen Planopilaris is a Common Scarring Alopecia among Iraqi Population," Journal of Cosmetics, Dermatological Sciences and Applications, Vol. 3 No. 3, 2013, pp. 35-39. doi: 10.4236/jcdsa.2013.33A1005.

References

[1] D. N. Silvers, B. E. Katz and A. W. Young, “Pseudopelade of Brocq Is Lichen Planopilaris: Report of Four Cases That Support This Nosology,” Cutis, Vol. 51, No. 2, 1993, pp. 99-105.

[2] H. Kang, A. A. Alzolibani, N. Otberg and J. Shapiro, “Lichen Planopilaris,” Dermatology and Therapy, Vol. 21, No. 4, 2008, pp. 249-256. doi:10.1111/j.1529-8019.2008.00206.x

[3] E. A. Olsen, W. F. Bergfeld, G. Cotsarelis, V. H. Price, J. Shapiro, R. Sinclair, A. Solomon, L. Sperling, K. Stenn, D. A. Whiting, O. Bernardo, M. Bettencourt, C. Bolduc, V. Callendar, D. Elston, J. Hickman, M. Ioffreda, L. King, C. Linzon, A. McMichael, J. Miller, F. Mulinari and R. Trancik, “Summary of North American Hair Research Society (NAHRS)-Sponsored Workshop on Cicatricial Alopecia, Duke University Medical Center, February 10 and 11, 2001,” Journal of the American Academy of Dermatology, Vol. 48, 2003, pp. 103-110. doi:10.1067/mjd.2003.68

[4] K. E. Sharquie, M. M. Al-Waiz and A. A. Al-Nuaimy, “Striae Distensae-Like Lesions. A Cause of Scarring Alopecia among Children,” Saudi Medical Journal, Vol. 23, No. 12, 2002, pp. 1489-1491.

[5] E. L. Khoury, V. H. Price, M. M. Abdel-Salam, M. Stern and J. S. Greenspan, “Topical Minoxidil in Alopecia Areata: No Effect on the Perifollicular Lymphoid Infiltration,” Journal of Investigative Dermatology, Vol. 99, 1992, pp. 40-47. doi:10.1111/1523-1747.ep12611409

[6] E. Tan, M. Martinka, N. Ball and J. Shapiro, “Primary Cicatricialalopecias: Clinicopathology of 112 Cases,” Journal of the American Academy of Dermatology, Vol. 50, No. 1, 2004, pp. 25-32. doi:10.1016/j.jaad.2003.04.001

[7] N. Cevasco, W. Bergfeld, B. Remzi and H. Ramirez de Knott, “A Case-Series of 29 Patients with Lichen Planopilaris: The Cleveland Clinic Foundation Experience on Evaluation, Diagnosis, and Treatment,” Journal of the American Academy of Dermatology, Vol. 57, No. 1, 2007, pp. 47-53. doi:10.1016/ j.jaad.2007.01.011

[8] D. A. Mehregan, H. M. Van Hale and S. A. Muller, “Lichen Planopilaris: Clinical and Pathologic Study of FortyFive Patients,” Journal of the American Academy of Dermatology, Vol. 27, No. 6, 1992, pp. 35-42. doi:10.1016/0190-9622(92)70290-V

[9] W. F. Bergfeld and D. M. Elston, “Cicatricial Alopecia,” In: E. A. Olsen, Ed., Disorders of Hair Growth: Diagnosis and Treatment,” McGraw-Hill, New York, 2003, pp. 363-398.

[10] K. Wiedemeyer, W. B. Schill and C. Loser, “Diseases on Hair Follicles Leading to Hair Loss Part II: Scarring Alopecias,” Skinmed, Vol. 3, No. 5, 2004, pp. 266-269.

[11] M. Y. Bi, P. R. Cohen, F. W. Robinson and J. M. Gray, “Alopecia Syphilitica—Report of a Patient with Secondary Syphilis Presenting as Moth-Eaten Alopecia and a Review of Its Common Mimickers,” Dermatology Online Journal, Vol. 15, No. 10, 2009, p. 6.

[12] J. Y. Lee and M. L. Hsu, “Alopeciasyphilitica, a Simulator of Alopeciaareata: Histopathology and Differential Diagnosis,” Journal of Cutaneous Pathology, Vol. 18, No. 2, 1991, pp. 87-92. doi:10.1111/ j.1600-0560.1991.tb00133.x

[13] S. K. Clark, “Cutaneous Lupus Erythematosus, Recognition of Its Many Forms,” Postgraduate Medicine, Vol. 79, No. 5, 1986, pp. 195-203.

[14] M. K. Al-Hattab and M. Al-Waiz, “Discoid Lupus Erythematosus in Iraqi Patients: A Clinical and Histopathological Study,” Annals of Saudi Medicine, Vol. 24, No. 4, 2004, pp. 289-292.

[15] D. Whiting, “Cicatricial Alopecia: Clinico-Pathological Findings and Treatment,” Clinics in Dermatology, Vol. 19, No. 2, 2001, pp. 211-225. doi:10.1016/S0738-081X(00)00132-2

[16] N. Mobini, S. Tam and H. Kamino, “Possible Role of the Bulgeregion in the Pathogenesis of Inflammatory Scarring Alopecia: Lichenplanopilaris as the Prototype,” Journal of Cutaneous Pathology, Vol. 32, No. 10, 2005, pp. 675-679. doi:10.1111/j.0303-6987.2005.00399.x

[17] L. Sperling, “Scarring Alopecia and the Dermatopathologist,” Journal of Cutaneous Pathology, Vol. 28, No. 7, 2001, pp. 333-342. doi:10.1034/j.1600-0560.2001.280701.x